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  • Cardiac hypertrophy  (1)
  • PACS. 34.20.-b Interatomic and intermolecular potentials and forces, potential energy surfaces for collisions – 34.20.Gj Intermolecular and atom-molecule potentials and forces – 34.50.-s Scattering of atoms and molecules  (1)
  • continuous nonlinear programming  (1)
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  • 1
    ISSN: 1432-2307
    Schlagwort(e): Key words Microangiopathy ; Arteriolar density ; Fibrosis ; Remodelling ; Cardiac hypertrophy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Left ventricular hypertrophy is a risk factor for cardiovascular morbidity and mortality. In arterial hypertension and in hypertrophic cardiomyopathy it may be accompanied by clinical signs of myocardial ischaemia resulting from microcirculatory dysfunction in the absence of coronary macroangiopathy. Structural changes of the vascular and interstitial compartment of the heart are involved in the pathogenesis of impaired microcirculation. We investigated patients with hypertensive heart disease (HHD; n=12) and hypertrophic cardiomyopathy (HCM; n=19) without coronary macroangiopathy but with signs of myocardial ischaemia. Right septal endomyocardial biopsies were evaluated to quantify the structure of intramyocardial arterioles, collagen content and myocytic diameter by morphometric rules. Nine normotensive subjects served as controls. The groups differed significantly (P〈0.05) in myocytic diameter and total collagen content. The myocytic diameter correlated with the thickness of the interventricular septum. Arterioles in HHD showed a significant increase in cross-sectional medial area and in HHD patients the periarteriolar collagen area increased both in absolute terms and when standardized to medial area. Arteriolar density was significantly reduced in HCM. In a multivariate discriminant analysis the positive predictive value for differentiation of the groups by non-myocytic variables was 72.5% (P=0.013). HHD and HCM differ in the structural alterations in the arteriolar bed. Medial hypertrophy and periarteriolar fibrosis prevail in HHD, and reduced arteriolar density is found in HCM. Different microvascular remodelling at the level of arterioles indicates distinct pathophysiologic processes that may contribute to the clinically observed disturbance of coronary microperfusion in these two diseases.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    The European physical journal 15 (2001), S. 321-329 
    ISSN: 1434-6079
    Schlagwort(e): PACS. 34.20.-b Interatomic and intermolecular potentials and forces, potential energy surfaces for collisions – 34.20.Gj Intermolecular and atom-molecule potentials and forces – 34.50.-s Scattering of atoms and molecules
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract: The interaction between LiH and H has been calculated using a Coupled Cluster approach in view of examining the strength of the coupling between the impinging atom and the rovibrational LiH states in low energy collision regimes. The potential energy surface was thus obtained by considering not only the angular anisotropy but also the dependence of the interaction energy on the vibrational motion of the LiH molecule, hence producing the strength of the vibrational coupling. The main objective is that of gaining a realistic description of the interaction in the sub-reactive region. The results of our calculations show here that this interaction should be used in conjunction with that of the reactive configurational space because of the strong coupling between the non-reactive and the reactive channels in the present system makes the full reactive scattering calculations a more reliable way to obtain realistic cross-sections also for inelastic relaxation and excitation processes.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Journal of optimization theory and applications 24 (1978), S. 243-262 
    ISSN: 1573-2878
    Schlagwort(e): Complementarity ; continuous nonlinear complementarity ; continuous nonlinear programming ; continuous Kuhn-Tucker theorem
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik
    Notizen: Abstract The concept of continuous nonlinear complementarity is defined. Basic properties and existence theorem are proven. Applications to continuous linear and nonlinear programming are presented. Kuhn-Tucker type conditions are established.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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