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  • Chemistry  (1)
  • Paracellular water flow  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Pathways for volume flow and volume regulation in leaky epithelia (1985)
    Springer
    Pflügers Archiv 405 (1985), S. S17 
    Details
    ISSN: 1432-2013
    Schlagwort(e): Water osmotic permeability ; Leaky epithelia ; Paracellular water flow ; Osmotic equilibration ; Cell membrane pores ; Tubular permeability ; Epithelial water transport ; Kidney proximal tubule
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Continuous pathways must pierce the cell membrane to be used by water during osmotic equilibration between proximal straight tubular cells and the external medium, because a) the water osmotic permeability coefficient of the basolateral plasma membrane,P os cb , is high; b) its activation energy,E a, is as that of free water movement and c) pCMBS inhibits markedly (but reversibly)P os cb and increasesE a to values similar to those observed in lipid bilayers without pores. d) Preliminary measurements ofP d the water diffusive permeability coefficient using NMR indicate thatP os cb /P d is near 4–5. The following two observations indicate that a significant paracellular water flow must exist in leaky epithelia. Namely, a) large extracellular solutes are dragged by water in four leaky epithelia: gall bladder, Necturus proximal tubule, rat proximal tubule andRhodnius malpighian tubule. b) The transcellular water osmotic permeability coefficient is smaller than the transepithelial values available in the rabbit proximal straight tubule. This requires a significant paracellular permeability.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00581774
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Micellar effect upon the reaction of hydroxide ion with coumarin (1998)
    New York, NY : Wiley-Blackwell
    International Journal of Chemical Kinetics 30 (1998), S. 273-276 
    Details
    ISSN: 0538-8066
    Schlagwort(e): Chemistry ; Physical Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Cationic micelles of cetyltrimethylammonium bromide, CTABr, speed attack of hydroxide ion upon coumarin by a factor of c.a-2, due to a concentration effect. The first-order rate constants, kobs, at a given hydroxide ions concentration go through maxima with increasing surfactant concentration. The overall micellar effects in these cationic micelles can be treated in terms of the pseudo-phase ion exchange model. Analysis of the data shows that second-order rate constant at the micellar surface is smaller than the second-order rate constant in water. Anionic micelles of sodium dodecyi sulfate, SDS, inhibit the same reaction. © 1998 John Wiley & Sons, Inc. Int J Chem Kinet 30: 273-276, 1998.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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