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Etiology and pathophysiology of chronic transplant dysfunction (2000)

Kouwenhoven, Ewout A. ; IJzermans, J. N. M. ; de Bruin, Ron W. F.

Springer

Transplant international 13 (2000), S. 385-401

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ISSN: 1432-2277

Keywords: Keywords Chronic transplant dysfunction ; Etiology ; Pathophysiology ; Review

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract Chronic transplant dysfunction (CTD) is the predominant cause of late graft failure. The common histopathological feature in all transplanted organs is intimal hyperplasia accompanied by organ specific lesions. The knowledge about CTD is incomplete, and there is no therapy to prevent or treat it. This review describes the current knowledge on the etiology of CTD, with emphasis on kidney transplants, and postulates a pathophysiologic route through which CTD may develop.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/s001470050721

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