ISSN:
1432-0983
Keywords:
Ars sequence
;
Histone gene
;
Replication origin
;
Physarum polycephalum
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary Fragments of DNA with function as autonomous replication sequences in yeast were cloned from Physarum polycephalum. The ars activity is located in a 1.2 kbp fragment extanding 1.5 kbp to 2.7 kbp upstream of the 5′ end of a histone H4 gene. Our recent finding that a replication origin is located at a distance less than 3 kbp of this histone gene suggests that the ars element identified coincides with a specialized replication origin and can be used to direct chromosome replication in Physarum polycephalum.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00419874
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