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  • 1
    Electronic Resource
    Electronic Resource
    Comparative bioavailability of two different rectal preparations of piroxicam in man (1992)
    Springer
    European journal of clinical pharmacology 43 (1992), S. 315-317 
    Details
    ISSN: 1432-1041
    Keywords: Piroxicam, NSAID ; suppository, bioavailability, pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary A comparative pharmacokinetic study was performed with two types of suppository each containing 20 mg piroxicam. The bioavailability of piroxicam was studied in 24 healthy volunteers in a double blind, randomised, cross over study. No significant difference was found in the pharmacokinetic parameters [AUC(0–72 h), AUC, Cmax, t1/2β calculated from plasma concentration time curves, indicating that the two preparations were bioequivalent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02333031
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Characterization of Early Region 4 of Porcine Adenovirus Serotype 5 (2000)
    Springer
    Virus genes 20 (2000), S. 217-219 
    Details
    ISSN: 1572-994X
    Keywords: porcine adenovirus ; serotype 5 ; E4 region
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To locate the E4 region on the genome of the HNF-70 prototype strain of the porcine adenovirus serotype 5 (PAdV-5), 4.5 kb at the extreme right end was sequenced. This area had 11 open reading frames (ORFs) on the left strand encoding more than 50 amino acids (aa). A Genbank homology search indicated that 8 of these ORFs were unique to PAdV-5. ORF5:253 aa, ORF6:245 aa and ORF11:146 aa showed similarities to known mammalian and avian adenovirus E4 ORFs. The putative E4 promoter sequences were also identified. Two TATA boxes, several GC boxes and two typical CCAAT boxes were located within this region. The presence of several potential poly-adenylation signals and the number of E4 transcripts detected by Northern blot analysis suggested the possibility of a complex mRNA transcription.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008136411020
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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