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  • 1
    Electronic Resource
    Electronic Resource
    Estimation of the phospholipid distribution in the human platelet plasma membrane based on the effect of phospholipase A"2 from Naja nigricollis
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 856 (1986), S. 244-258 
    Details
    ISSN: 0005-2736
    Keywords: (Human, N. nigricollis) ; Electron microscopy ; Phospholipase A"2 ; Phospholipid asymmetry ; Platelet membrane
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(86)90034-9
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  • 2
    Electronic Resource
    Electronic Resource
    The aggregation of human platelet induced by ganodermic acid S
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 986 (1989), S. 151-160 
    Details
    ISSN: 0005-2736
    Keywords: (Human blood) ; Aggregation ; Electron microscopy ; Ganodermic acid S ; Phosphoinositide metabolism ; Platelet membrane
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0005-2736(89)90285-X
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  • 3
    Electronic Resource
    Electronic Resource
    The mode of action of primary bile salts on human platelets
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 1146 (1993), S. 282-293 
    Details
    ISSN: 0005-2736
    Keywords: (Human blood) ; Aggregation ; Component solubility ; Electron microscopy ; Leakage ; Optical absorbance ; Platelet membrane ; Primary bile salt
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(93)90367-9
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  • 4
    Electronic Resource
    Electronic Resource
    Changes in both calcium pool size and morphology of human platelets incubated in various concentrations of calcium ion. Calcium-specific bleb formation on platelet-membrane surface
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 940 (1988), S. 105-120 
    Details
    ISSN: 0005-2736
    Keywords: (Human blood) ; Bleb formation ; Calcium ion flux ; Electron microscopy ; Platelet membrane
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(88)90014-4
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  • 5
    Electronic Resource
    Electronic Resource
    Filter Banks and Neural Network-based Feature Extraction and Automatic Classification of Electrogastrogram (1999)
    Springer
    Annals of biomedical engineering 27 (1999), S. 88-95 
    Details
    ISSN: 1573-9686
    Keywords: Electrogastrography ; Gastric motility ; Stomach ; Filter banks ; Neural networks
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Dysrhythmia in gastric myoelectrical activity has been frequently observed in patients with gastric motor disorders and gastrointestinal symptoms. The assessment of the regularity of gastric myoelectrical activity is of great clinical significance. The aim of this study was to develop an automated assessment method for the regularity of gastric myoelectrical activity from the surface electrogastrogram (EGG). The method proposed in this paper was based on the filter bank and neural network. First, the EGG signal was divided into frequency subbands using filter bank analysis. Second, a parameter called the subband energy ratio (SER) was computed for each subband signal. A multilayer perceptron neural network was then used to automatically classify the EGG signal into four categories: bradygastria, normal, tachygastria, and arrhythmia, using the SER as the input. The EGG recording was made using the standard method of electrogastrography by placing electrodes on the abdominal surface. The study was performed in 40 patients with various gastric motor disorders, ten healthy adults, and ten healthy children. The neural network was trained and tested using the EGG data obtained from the patients. The regularity of gastric myoelectrical activity was assessed based on the classification of the minute-by-minute EGG segments. Using the running spectral analysis method as a gold standard, the proposed automated method had an accuracy of 100% for the training set and 97% for the test set. It was concluded that the proposed method provides an accurate and automatic assessment of the regularity of gastric myoelectrical activity from the EGG. © 1999 Biomedical Engineering Society. PAC99: 8780-y, 8717-d, 0705Mh, 0270Hm
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1114/1.151
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  • 6
    Electronic Resource
    Electronic Resource
    Solute-membrane interactions in hyperfiltration (1987)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 33 (1987), S. 1809-1822 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The performances of several composite membranes (PEC-1000, Teijin, HR-95, HR-98) and one asymmetric membrane (Solrox SC-200) in hyperfiltration are compared at 25°C using different aqueous feed solutions (0.1M and 0.5M NaCl, 0.5M 1,3-and 1,4-dioxan, 0.1M benzyl alcohol and 2-methoxybenzyl alcohol, 1,2- and 1,4-butandiol, and Triton feed solution). The effects of solute dissociation, polarization, and hydrogen bonding ability on solute permeability are discussed; steric effects are also being considered. Strong solute-membrane interactions are exhibited in hyperfiltration by systems with distinct hydrogen bonding capabilities of the solute with functional sites of the membrane matrix. Knowledge of solute-membrane interactions can be useful for elaborating separation and transport mechanisms.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1987.070330532
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  • 7
    Electronic Resource
    Electronic Resource
    Adaptive spectral analysis of cutaneous electrogastric signals using autoregressive moving average modelling (1990)
    Springer
    Medical & biological engineering & computing 28 (1990), S. 531-536 
    Details
    ISSN: 1741-0444
    Keywords: Autoregressive moving average modelling ; Electrogastrography ; Gastric motility ; Gastric slow wave ; Spectral analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The recording of the human, gastric myoelectrical activity, by means of cutaneous electrodes is called electrogastrography (EGG). It provides a noninvasive method of studying electrogastric behaviour. The normal frequency of the gastric signal is about 0·05 Hz. However, sudden changes of its frequency have been observed and are generally considered to be related to gastric motility disorders. Thus, spectral analysis, especially online spectral analysis, can serve as a valuable tool for practical purposes. The paper presents a new method of the adaptive spectral analysis of cutaneous electrogastric signals using autoregressive moving average (ARMA) modelling. It is based on an adaptive ARMA filter and provides both time and frequency information of the signal. Its performance is investigated in comparison with the conventional FFT-based periodogram method. Its properties in tracking time-varying instantaneous frequencies are shown. Its applications to the running spectral analysis of cutaneous electrogastric signals are presented. The proposed adaptive ARMA spectral analysis method is easy to implement and is efficient in computations. The results presented in the paper show that this new method provides a better performance and is very useful for the online monitoring of cutaneous electrogastric signals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442603
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  • 8
    Electronic Resource
    Electronic Resource
    Synthesis and properties of copolymers from 2-hydroxyethyl methacrylate-linked nonsteroidal antiinflammatory agents with methacrylic acid (1998)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 36 (1998), S. 1481-1490 
    Details
    ISSN: 0887-624X
    Keywords: ibuprofen ; ketoprofen ; naproxen ; copolymer reactivity ; thermal stability ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Three nonsteroidal antiinflammatory drugs, 2-(4-isobutylphenyl)-propionic acid (ibuprofen), 2-(3-benzoylphenyl)-propionic acid (ketoprofen), and 2-(6-methoxy-2-naphthyl)-propionic acid (naproxen), were covalently linked with 2-hydroxyethyl methacrylate (HEMA). The drug-linked HEMA (M1) (ibuprofen-linked HEMA abbreviated as HI; ketoprofen-linked HEMA as HK, and naproxen-linked HEMA as HN), were respectively copolymerized with methacrylic acid (M2), MA, to obtain macromolecular prodrugs. The compositions of the copolymers were determined by means of a 1H-NMR spectroscopy and monomer reactivity ratios were estimated using the Kelen-Tüdös linear differential equation. The reactivity ratios are: r1 = 0.101 ± 0.012, r2 = 1.071 ± 0.065 for HI-MA; r1 = 0.344 ± 0.066, r2 = 0.966 ± 0.032 for HN-MA, and r1 = 0.650 ± 0.182, r2 = 1.032 ± 0.106 for HK-MA, respectively. The monomer reactivity toward to MA radical estimated from 1/r2 values is almost same for all three monomers (1/r2 ∼ 1). The glass transition temperatures of three drug-linked homopolymers go hand in hand with the steric hindrance of three drugs, i.e., ketoprofen 〉 naproxen ≫ ibuprofen calculated the minimum energy by computer molecular modeling. © 1998 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 36: 1481-1490, 1998
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    A study on the plasma polymerization of some cyano-containing compounds and their electrical properties (1989)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 27 (1989), S. 3799-3809 
    Details
    ISSN: 0887-624X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Plasma polymerization of some cyano-containing organic compounds was carried out at 13.56 MHz from the gas phase. The resulting polymer films were smooth and pinhole free. The electrical conductivities of the polymer films varied from 10-12 to 10-7 S cm-1 depending upon which cyano-containing monomer was used. The Al/polymer film/ITO (indium-tin oxide) sandwich cells made from the films demonstrated a photovoltaic effect, and some of them showed good rectifying behavior. Infrared spectroscopy (IR) and ultraviolet spectroscopy (UV) were utilized to characterize the structure of the product polymers. The effects of the original structure in the starting monomers on the structure of the resulting polymers are investigated. The influence of incident light intensity on the photovoltaic characteristics was also investigated.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pola.1989.080271120
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  • 10
    Electronic Resource
    Electronic Resource
    Optimized Overcomplete Signal Representation and its Applications to Time-frequency Analysis of Electrogastrogram (1998)
    Springer
    Annals of biomedical engineering 26 (1998), S. 859-869 
    Details
    ISSN: 1573-9686
    Keywords: Spectral analysis ; Matching pursuit ; Stomach ; Gastric motility ; Electrogastrography ; Evolutionary programming ; Signal analysis ; Electrogastrogram
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract The electrogastrogram (EGG) is a surface measurement of gastric myoelectrical activity. The normal frequency of gastric myoelectrical activity in humans is 3 cycles/min. Abnormal frequencies in gastric myoelectrical activity have been found to be associated with functional disorders of the stomach. The aim of this article was, therefore, to develop new time-frequency analysis methods for the detection of gastric dysrhythmia from the EGG. A concept of overcomplete signal representation was used. Two algorithms were proposed for the optimization of the overcomplete signal representation. One was a fast algorithm of matching pursuit and the other was based on an evolutionary program. Computer simulations were performed to compare the performance of the proposed methods in comparison with existing time-frequency analysis methods. It was found that the proposed algorithms provide higher frequency resolution than the short time Fourier transform and Wigner-Ville distribution methods. The practical application of the developed methods to the EGG is also presented. It was concluded that these methods are well suited for the time-frequency analysis of the EGG and may also be applicable to the time-frequency analysis of other biomedical signals. © 1998 Biomedical Engineering Society. PAC98: 8780+s, 0705Kf
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1114/1.69
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