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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 369 (1977), S. 65-73 
    ISSN: 1432-2013
    Keywords: Carotid sinus nerve ; Primary afferent fibres ; Nucleus of the tractus solitarius ; C-fibres ; Antidromic potentials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Compound action potentials evoked by electrical stimulation in the brainstem of anaesthetized, paralyzed cats and rabbits were recorded distally in the carotid sinus nerve. The latencies of the components of the responses were indicative of fibres with conduction velocities between 0.5 and 32 m/s. These include both myelinated and unmyelinated fibres. Using histological reconstructions of the ‘responsive sites’, the termination of the primary afferent fibres of the sinus nerve within the medulla was mapped. In both cat and rabbit these responsive sites were restricted to thedorsomedial medulla in the vicinity of the NTS 0–3 mm rostral to the obex. Although in the cat the fast conducting myelinated fibres (conduction velocities 〉12.5 m/s) were discretely localized to the ventrolateral area of the NTS, the slower conducting myelinated and unmyelinated fibres were found more diffusely, spreading into areas dorsal and medial to the NTS. In the rabbit the terminals of all types of fibre were mainly confined to the NTS although some C fibres appeared to be grouped in the juxta-alar region. Responses were never evoked from the medial reticular formation or nucleus ambiguus in either cats or rabbits. The organization of the sinus nerve input to the medulla is discussed in the light of these results.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Polymer Science 9 (1952), S. 286-288 
    ISSN: 0022-3832
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Biopolymers 10 (1971), S. 399-410 
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The influence of temperature on the binding of 9-aminoacridine and of proflavine to E. coli DNA in 10-3M NaCl solution has been determined by a spectrophotometric technique. The inadequacy of the expression normally used for the determination of the extent of binding is discussed with reference to measurements at temperatures above which dissociation of the double helix occurs. A method of determining the relative extents of binding to native and denatured DNA at elevated temperatures is described.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Biopolymers 11 (1972), S. 1661-1684 
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: DNA which has been heat denatured in the presence of Cu++ ions can be completely and rapidly renatured by increasing the ionic strength of the solution above a critical value. A kinetic study of this renaturation recation was carried out by following the associated UV absorbance change and also by following the change in free Cu++ ion concentration by means of a specific Cu++ ion activity electrode. The data obtained could be fitted to first-order kinetics for a considerable extent of the reaction and the rate constant was found to increase with temperature and ionic strength, but to decrease markedly as the bulk viscosity of the solution was increased. At temperatures greater than 5°C the reaction rate depended on the time elapsing between denaturation and the commencement of the renaturation reaction. As there was good agreement between the rate constants obtained by following the decrease in hyperchromism and by following the increase in free Cu++ ion concentration, it is concluded that under the conditions employed, the rate of renaturation is determined by the rate of release of Cu++ ions from the denatured DNA-Cu++ complex.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Polymer Science 12 (1954), S. 209-219 
    ISSN: 0022-3832
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The sedimentation constants and diffusion coefficients of sodium polymethacrylate and of polymethacrylic acid have been determined at various concentrations of polymer and of added electrolyte and the nature of the charge effects is considered. A ratio y = (molarity of added electrolyte)/(grundmolarity of polymer) is used to obtain S20 at y = ∞ when the polyelectrolyte is assumed to be uncharged. The variation of the effective radius with y is considered not to be due to asymmetry but to the open network nature of the polyelectrolyte coil.The sedimentation constant of unionized polymethacrylic acid is determined and also the variation of sedimentation constant with degree of ionization.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Polymer Science 21 (1956), S. 463-472 
    ISSN: 0022-3832
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The viscosity, streaming birefringence, and sedimentation of a sample of poly-4-vinyl-N-n-butylpyridinium bromide have been measured in aqueous and in sodium chloride solutions. The theory of Peterlin for concentrated solutions has been found to be in agreement with the results. Values of the molecular weight have been calculated by different methods and a value of 9 × 105 has been chosen.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Polymer Science 21 (1956), S. 473-482 
    ISSN: 0022-3832
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The hydrodynamic properties of fractionated samples of poly-4-vinylpyridine have been studied. The intrinsic viscosities and the Huggins' constant (k′) have been obtained. The effect of shear on the viscosity disappears at high dilution. The sedimentation constants (S0) have been measured, and the streaming birefringence has been investigated at various concentrations and shear gradients. The Peterlin theory for concentrated solutions is in good agreement with the results for the orientation angle, but is not so well in accord with the magnitude of the birefringence. The partial specific volume is low (0.685). Molecular weights have been calculated for the fractions, and it is concluded that the shape of the molecules in solution approximates to that of a stiff coil.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science Part A: General Papers 3 (1965), S. 1941-1948 
    ISSN: 0449-2951
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The concentration dependence of the reduced viscosity has been studied for several polyelectrolytes in conductivity water. It is shown that the viscosity maximum previously reported for polyelectrolyte solutions without added electrolyte can be explained either by the presence of ionic impurities in the solvent or by the contamination of the solutions. It is concluded that the folding chain theory of polyelectrolyte solutions requires amendment to account for the experimental results on counterion association. A suggested amendment to the theory implies that the application of the Huggins equation to the concentration dependence of polyelectrolyte solutions in the presence of added electrolyte may not lead to information concerning the interactions between the polyions in solution.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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