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  • 1
    Digitale Medien
    Digitale Medien
    Lysinuric protein intolerance in pregnancy: case report with successful outcome (1995)
    Springer
    Archives of gynecology and obstetrics 256 (1995), S. 49-52 
    Details
    ISSN: 1432-0711
    Schlagwort(e): Lysinuric protein intolerance ; Anemia ; Thrombocytopenia ; Hyperammonemia ; Pregnancy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We present a 28-year-old pregnant woman who exhibited intolerance to lysinuric protein. However, she gave birth to a normal child without serious maternal complications. Since four of seven similar patients reported previously developed serious complications such as hemorrhage and eclampsia, patients with lysinuric protein intolerance are considered to be at high risk during pregnancy. A successful outcome can be achieved, provided that the anemia, thrombocytopenia, toxemia and hyperammonemia are well controlled.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00634350
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Lysinuric protein intolerance in pregnancy: case report with successful outcome (1995)
    Springer
    Archives of gynecology and obstetrics 256 (1995), S. 49-52 
    Details
    ISSN: 1432-0711
    Schlagwort(e): Key words: Lysinuric protein intolerance ; Anemia ; Thrombocytopenia ; Hyperammonemia ; Pregnancy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract. We present a 28-year-old pregnant woman who exhibited intolerance to lysinuric protein. However, she gave birth to a normal child without serious maternal complications. Since four of seven similar patients reported previously developed serious complications such as hemorrhage and eclampsia, patients with lysinuric protein intolerance are considered to be at high risk during pregnancy. A successful outcome can be achieved, provided that the anemia, thrombocytopenia, toxemia and hyperammonemia are well controlled.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00634350
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
    Volltext
  • 3
    Digitale Medien
    Digitale Medien
    Caudal ventrolateral medulla (1985)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 328 (1985), S. 368-372 
    Details
    ISSN: 1432-1912
    Schlagwort(e): Ventrolateral medulla ; Spinal transection ; Pressor response ; Glutamate ; Kainic acid ; Vasopressin antagonist
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary We localized glutamate-sensitive sites in the ventrolateral medulla of the rat with the spinal cord cut at C1. When unilaterally injected into a circumscribed region of the caudal ventrolateral medulla,l-glutamate (30–300 ng) elicited a dose-dependent increase in arterial pressure. The pressor response was accounted for by an increased release of vasopressin because it was abolished by the intravenous injection of a vasopressin antagonist. Bilateral microinjections of kainic acid (50 ng) into the ventrolateral glutamate-sensitive area markedly reduced a vasopressin-induced pressor response to kainic acid (30 ng), injected bilaterally into the nucleus tractus solitarii. It is concluded that the glutamate-sensitive neurons in the caudal ventrolateral medulla are involved in mediation of the vasopressin-induced pressor response arising from the nucleus tractus solitarii.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00692902
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Excitatory amino acid receptors in the rostral ventrolateral medulla mediate hypertension induced by carotid body chemoreceptor stimulation (1994)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 349 (1994), S. 549-554 
    Details
    ISSN: 1432-1912
    Schlagwort(e): Kynurenate ; Excitatory amino acid receptor ; Vasopressin ; Chemoreceptor ; Vasopressin antagonist ; Rostral ventrolateral medulla ; Carotid body ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The rostral ventrolateral medulla (RVLM) is involved in the mediation of cardiovascular responses to peripheral chemoreceptor stimulation. To investigate whether excitatory amino acid inputs in the RVLM are related to the responses to chemoreceptor stimulation, we microinjected kynurenate, an amino acid antagonist, unilaterally into the RVLM and examined its effects on the pressor response to stimulation of carotid body chemoreceptors. Male Wistar rats were anesthetized with urethane, paralyzed and artificially ventilated. The carotid chemoreceptors were stimulated with isotonic solutions of inorganic phosphate solution. Stimulation of carotid body chemoreceptors produced increases in blood pressure. Kynurenate injected ipsilaterally but not contralaterally into the RVLM markedly inhibited the pressor response to chemoreceptor stimulation. In rats with spinal transection, stimulation of carotid body chemoreceptors also produced increases in blood pressure. The pressor response in rats with spinal transection was inhibited by intravenous injection of a vasopressin antagonist or by kynurenate injected ipsilaterally into the RVLM. Kynurenate injected into the RVLM inhibited the pressor response to NMDA, AMPA and kainate but not to acetylcholine in intact rats. These findings indicate that excitatory amino acid receptors are involved in mediating the pressor response to carotid body chemoreceptor stimulation in the rat RVLM. It appears that the chemoreceptor stimulation produces an increase in vasopressin release and the enhancement of vasopressin release is also mediated by an increase in excitatory amino acid inputs in the RVLM.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01258457
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