ISSN:
1432-1076
Keywords:
Pregnancy
;
Liver transplantation
;
Newborn
;
Immune system
;
Cyclosporin A
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Pregnancy in transplant recipients is not uncommon. Cyclosporin A may be used as an immunosuppressive drug in these patients. Almost no data exist on the effects of cyclosporin A on the immune system of infants who have been exposed to this drug in utero. The infant of a liver transplant recipient was followed during the first 2 years of life. Shortly after birth all lymphocyte subsets were low, especially for B-cells. The distribution of lymphocytes returned to low normal ranges within the first 2 years of life, except for CD8 values that stayed below normal. There were no signs of persistent adverse effects of cyclosporin A on the functional integrity of the immune system.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01955053
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