ISSN:
1432-1432
Keywords:
Chromatin structure
;
Regulation
;
Structural computations
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary Calculations of DNA angular parameters in 50 eukaryotic sequences reveal regions of large conformational deviations from ideal DNA around regulatory sites. Frequently, discrete peaks of structural variation are present upstream of genes. Known regulatory regions often include variants of consensus sequences. Thus, imprecise sequences and structures are recognized within large genomic stretches. The existence of structurally “wrinkled” regions in the vicinity of regulatory sequences is likely to facilitate greatly their recognition by proteins and enzymes.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02101693
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