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  • Dark cell  (2)
  • Saccule  (2)
  • Ca++ transport  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    European archives of oto-rhino-laryngology and head & neck 243 (1987), S. 417-423 
    ISSN: 1434-4726
    Schlagwort(e): Ca++-ATPase ; Ca++ transport ; Cytochemistry ; Dark cell ; Guinea pig
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary We used ultracytochemistry to examine Ca++-ATPase activity in the vestibular epithelia of the guinea pig. Many reaction products were found along the basolateral plasma membrane of the vestibular dark cell. There were also marked reaction deposits on the apical and lateral cell membranes of the transitional cells, and the utricular and saccular wall cells. Both sensory and supporting cells showed Ca++-ATPase activity along their ciliary membrane and apical-lateral cell surfaces. Our findings indicate that the Ca++-ATPase activity found on the plasma membrane is closely related to Ca++-transport across the plasma membrane. When either Ca++ or ATP was omitted from the incubation medium, enzyme activity (as seen by the staining reaction present) was completely abolished. Our present results suggest that Ca++-ATPase located in the vestibular epithelia plays a significant role in the regulation of the Ca++-concentration in the vestibular endolymph.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    European archives of oto-rhino-laryngology and head & neck 244 (1987), S. 143-146 
    ISSN: 1434-4726
    Schlagwort(e): Saccule ; Vertical optokinetic nystagmus ; Squirrel monkey
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary After bilateral sacculectomies, the squirrel monkey's vertical optokinetic nystagmus showed a gain increase of slow-phase down-nystagmus and a gain decrease of the slow-phase up-nystagmus. The nystagmus beating field of the former shifted upward but that of the latter did not change clearly. These results are in general agreement with the findings in man during the recent shuttle flight and indicate the functional linkage of saccular afferents to the vertical optokinetic nystagmus.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    European archives of oto-rhino-laryngology and head & neck 247 (1990), S. 274-276 
    ISSN: 1434-4726
    Schlagwort(e): Saccule ; Vertical optokinetic after-nystagmus ; Squirrel monkey
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The effect of bilateral saccular ablation on the asymmetry of vertical optokinetic after-nystagmus (OKAN) was studied in squirrel monkeys. No significant changes occurred in the initial slow-phase eye velocity (SPEV) or the time constant of the upward or downward OKAN first phase (OKAN-I) under various stimulus conditions. However, with a protracted downward stimulus, the maximum SPEV and the number of beats of the slow-phase-up OKAN second phase (OKAN-II) significantly increased. This increase should be the result from enhancement of the downward optokinetic input. In contrast, there was only minimal change in the slow-phase-down OKAN-II. Thus, the asymmetrical dominance of the vertical OKAN (dominance upward) remained the same after saccular deafferentation.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    European archives of oto-rhino-laryngology and head & neck 243 (1987), S. 401-402 
    ISSN: 1434-4726
    Schlagwort(e): Na+, K+-ATPase ; Tegmentum vasculosum ; Dark cell
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary We studied the localization of Na+, K+-ATPase activity in the chick cochlea, utilizing a cytochemical method of K+-p-nitrophenylphosphatase (K+-NPPase), and found that the enzyme activity was limited to the dark cells of the tegmentum vasculosum (TV). Our present results indicate that the dark cells of the TV play an essential role in the maintenance of the ionic composition of the cochlear endolymph.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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