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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 90 (1995), S. 164-169 
    ISSN: 1432-0533
    Keywords: Monocyte ; Scrapie ; Central nervous system ; Pathogenesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The recruitment of monocytes into the scrapie-affected brain was investigated in female mice reconstituted with male bone marrow, using a Y-chromosome-specific probe and F4/80 immunocytochemistry. Recruitment of monocytes could be demonstrated in six out of eight animals and the number of recruited cells correlated with the severity of vacuolation in most, but not all, animals. The proportion of microglia derived from recruited monocytes varied between individual animals, did not correlate with the increase in cellularity (glia) in affected areas of brain and did not affect the length of incubation period. Thus, it is unlikely that the recruitment of monocytes is a pivotal event in the development of early pathological changes in scrapie. The morphology of recruited cells in scrapie lesions, as revealed by F4/80 immunoreactivity, was indistinguishable from that of activated resident microglia.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 90 (1995), S. 164-169 
    ISSN: 1432-0533
    Keywords: Key words Monocyte ; Scrapie ; Central nervous ; system ; Pathogenesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The recruitment of monocytes into the scrapie-affected brain was investigated in female mice reconstituted with male bone marrow, using a Y-chromosome-specific probe and F4/80 immunocytochemistry. Recruitment of monocytes could be demonstrated in six out of eight animals and the number of recruited cells correlated with the severity of vacuolation in most, but not all, animals. The proportion of microglia derived from recruited monocytes varied between individual animals, did not correlate with the increase in cellularity (glia) in affected areas of brain and did not affect the length of incubation period. Thus, it is unlikely that the recruitment of monocytes is a pivotal event in the development of early pathological changes in scrapie. The morphology of recruited cells in scrapie lesions, as revealed by F4/80 immunoreactivity, was indistinguishable from that of activated resident microglia.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Water, air & soil pollution 98 (1997), S. 119-139 
    ISSN: 1573-2932
    Keywords: litter clearance and accumulation ; riverine litter ; time of travel
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Aspects of litter movement were looked at in a variety of ways. River bank clearances provided valuable information on litter accumulation and movement, showing a distinctive correlation between flood events and litter movement. Introduction of litter outside of channel deposition (diffuse sources) were limited in the study area in South Wales, UK. A rise in litter deposition occurred for some time after flood events, with the main accumulation occurring in the mid-bank zone. As only some litter types have an increased input during flood events e.g. sewage-derived material from combined sewer outfalls (CSO), accumulation of other litter types, e.g. plastic sheeting could be due to their distribution throughout the catchment. A positive correlation between litter stranding and vegetation was found. During high flows, (75.59 cumecs) litter is removed from sites with little restraining vegetation and deposited where stranding potential is high. Smaller items such as feminine hygiene products were more susceptible to stranding than larger plastic sheeting.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Water, air & soil pollution 98 (1997), S. 119-139 
    ISSN: 1573-2932
    Keywords: litter clearance and accumulation ; riverine litter ; time of travel
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Aspects of litter movement were looked at in a variety of ways. River bank clearances provided valuable information on litter accumulation and movement, showing a distinctive correlation between flood events and litter movement. Introduction of litter outside of channel deposition (diffuse sources) were limited in the study area in South Wales, UK. A rise in litter deposition occurred for some time after flood events, with the main accumulation occurring in the mid-bank zone. As only some litter types have an increased input during flood events e.g. sewage-derived material from combined sewer outfalls (CSO), accumulation of other litter types, e.g. plastic sheeting could be due to their distribution throughout the catchment. A positive correlation between litter stranding and vegetation was found. During high flows, (75.59 cumecs) litter is removed from sites with little restraining vegetation and deposited where stranding potential is high. Smaller items such as feminine hygiene products were more susceptible to stranding than larger plastic sheeting.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
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