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  • 1
    Electronic Resource
    Electronic Resource
    The neo-synovial membrane of patients with active rheumatoid arthritis at resynovectomy (1990)
    Springer
    Rheumatology international 10 (1990), S. 191-198 
    Details
    ISSN: 1437-160X
    Keywords: Rheumatoid arthritis ; Synovitis ; Synovial membrane ; Neo-synovial membrane ; Resynovectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neo-synovial membranes, which formed after “primary” synovectomy in 21 patients with rheumatoid arthritis (RA), were studied at resynovectomy. The clinical, histomorphological, and immunohistological data were compared with data derived from “primary” synovial membranes from RA and osteoarthritis (OA) patients. The clinical data suggest a less active rheumatoid inflammatory response after synovectomy. Histomorphologicaly, the synovitis in resynovectomized neosynovial membranes of RA revealed no qualitative differences when compared with synovitis in the “primary” synovium. However, the degree of the inflammatory rection evaluated by the different parameters was found to be distinctly lower. The immunohistological data correlated with these findings.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02274832
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Quantitative photometrical assessment of iron deposits in synovial membranes in different joint diseases (1996)
    Springer
    Rheumatology international 15 (1996), S. 211-216 
    Details
    ISSN: 1437-160X
    Keywords: Iron deposits ; Rheumatoid arthritis ; Osteoarthritis ; Synovitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated 86 synovial membranes from patients suffering either from rheumatoid arthritis (RA) or osteoarthritis (OA). Iron deposits in the synovial membrane were stained by the Prussian blue reaction, and the amount of stained iron was quantitatively assessed by microscope photometry. We found a statistically significant increase in iron deposits in the synovial membrane of RA patients when compared to OA patients. The amount of iron deposits correlated with the histological subtype of synovitis, those presenting with more exudative and proliferative features showing greater amounts of iron deposits. We also observed an inverse correlation between the haemoglobin concentration and erythrocytes in the serum and the amount of iron in the synovial membrane. From our data we concluded that iron deposits in the synovial membrane can contribute by several mechanisms, including activation of oxygen radicals, to the chronic inflammatory reaction in RA synovitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00290523
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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