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  • 1
    ISSN: 1432-1459
    Keywords: Ischaemic conduction block ; Small fibre function ; Thermal perception ; Resistance to ischaemia ; Mitochondrial encephalomyopathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thermal thresholds were measured during ischaemic compression block in the left forearms of 26 healthy subjects, 10 patients with diabetes mellitus and 6 patients suffering from different kinds of mitochondrial disorders. Cold and warm thresholds in the 6 patients with deficiencies in the respiratory chain increased earlier than in normals. When cold perception was impaired, cold stimuli were perceived as warmth and pinprick perception attenuated. In diabetics cold thresholds were less elevated during ischaemic block than in controls. This was paralleled by tingling paraesthesiae in all groups. The findings show that higher resistance to ischaemic nerve-fibre block in diabetes mellitus is not exclusively based on increased anaerobic metabolism.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 237 (1990), S. 295-299 
    ISSN: 1432-1459
    Keywords: Diabetic polyneuropathy ; Ischaemic conduction block ; Pain ; Small fibre function ; Thermal perception
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Thermal thresholds were measured in the left forearms of 26 healthy subjects and 10 patients with diabetes mellitus during ischaemic compression block. During the period when ischaemic block of large fibres caused paraesthesia and loss of touch sensation, the cold threshold rose in normals. The cold threshold was less clearly elevated and the warm perception remained unaltered by ischaemia in diabetics. These results show that not only large afferent and efferent nerve fibres but also thinly myelinated Aδ and unmyelinated C fibres are resistant to ischaemia in the diabetic nerve.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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