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  • 1
    ISSN: 1432-198X
    Keywords: Ultrafiltration ; Peritoneal dialysis ; Tidal peritoneal dialysis ; Continuous cycling peritoneal dialysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Dialysed infants are sometimes characterized by a hyperpermeable peritoneal state. In this situation decreasing dwell time and/or increasing dialysate tonicity are usually proposed to achieve adequate ultrafiltration (UF). We have investigated UF capacity under different peritoneal dialysis modalities in three infants. UF was not obtained with isotonic continuous ambulatory peritoneal dialysis (CAPD), and was only achieved with short dwell times and hypertonic CAPD. For the prescription of automated peritoneal dialysis, a shorter dwell time of hourly sequences is needed, which consequently decreases the phosphate diffusion time. Continuous cycling peritoneal dialysis with sequences of 1 h allowed efficient UF [UF/glucose absorption (UF/G) 4.2±0.9] but the dialysate/plasma (D/P) phosphate ratio was low (0.47±0.12). In contrast, tidal peritoneal dialysis gave a better UF/G ratio (6.8±0.7) without a decrease in the D/P phosphate ratio (0.64±0.18).
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-198X
    Keywords: Key words: Posture ; Intraperitoneal pressure ; Peritoneal permeability ; Upright position ; Supine position
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The posture of the patient influences both the intraperitoneal pressure (IPP) and the peritoneal permeability. We have studied the effects of the supine and the upright position in six children. Two peritoneal equilibration tests (PET) of 90-min dwell time each were performed consecutively, firstly in the supine position and then in the upright position. The same amount of dialysate was instilled (1,000 ml/m2; isotonic 1.36% dextrose) for each PET. Using the same filling volume, the IPP was significantly higher in the upright position (18.4±4.8 cm H2O) than in the supine position (8±2.4 cm H2O). The mean percentage IPP increase was 130%±35%. The decline in glucose resorption rate from the dialysate during the PET was significantly lower in the upright position. Despite this greater relative loss of osmotic gradient in the upright than the supine position, no significant difference in net ultrafiltration was noted after 90 min of dwell. The peritoneal equilibration ratio during the PET was lower in the upright than the supine position for urea, creatinine, and phosphate. These results favor performing peritoneal dialysis in a supine position, both to increase dialysis efficiency and to reduce patient discomfort.
    Type of Medium: Electronic Resource
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