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  • Type 1 (insulin-dependent) diabetes mellitus  (2)
  • time of travel  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Loss of regular oscillatory insulin secretion in islet cell antibody positive non-diabetic subjects (1992)
    Springer
    Diabetologia 35 (1992), S. 32-38 
    Details
    ISSN: 1432-0428
    Keywords: Type 1 (insulin-dependent) diabetes mellitus ; islet-cell antibodies ; insulin secretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Basal insulin secretion was compared in nine islet-cell antibody positive, non-diabetic first-degree relatives of children with Type 1 (insulin-dependent) diabetes mellitus and nine normal control subjects matched for age, sex and weight. Acute insulin responses to a 25 g intravenous glucose tolerance test were similar in the two groups (243 (198–229) vs 329 (285–380) mU·l−1·10min−1, mean (±SE), p=0.25). Fasting plasma insulin was assayed in venous samples taken at one min intervals for 2 h. Time series analysis was used to demonstrate oscillatory patterns in plasma insulin. Autocorrelation showed that regular oscillatory activity was generally absent in the islet-cell antibody positive group, whereas a regular 13 min cycle was shown in control subjects (p〈 0.0001). Fourier transformation did, however, show a 13 min spectral peak in the islet-cell antibody positive group, consistent with intermittent pulsatility. We conclude that overall oscillatory patters of basal insulin secretion are altered in islet-cell antibody positive subjects even when the acute insulin response is within the normal range.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00400849
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Raised temperature reduces the incidence of diabetes in the NOD mouse (1990)
    Springer
    Diabetologia 33 (1990), S. 635-637 
    Details
    ISSN: 1432-0428
    Keywords: Type 1 (insulin-dependent) diabetes mellitus ; environmental temperature ; non-obese diabetic (NOD) mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An association between the incidence of childhood Type 1 (insulin-dependent) diabetes mellitus and the average yearly temperature in different countries has been reported, the incidence being higher in countries with a lower mean temperature. We have studied the effect of environmental temperature on the incidence of diabetes in an animal model of Type 1 diabetes, the non-obese diabetic (NOD) mouse. Female NOD mice were divided at weaning, with one group placed at a higher temperature (mean 23.7±1.7° C) and the other at a lower temperature (21.0±1.8° C). At 20 weeks of age 6 of 16 mice at lower temperature and 1 of 17 mice at higher temperature had developed diabetes (p 〈 0.02); at 30 weeks 10 of 16 and 5 of 17 mice had developed diabetes (p 〈 0.05). Non-diabetic animals in the low temperature group had a higher food intake than those in the high temperature group between 13–15 weeks of age (28.0±1.2 g/week vs 24.8± 0.7 g/week, P 〈 0.05). In a parallel experiment, histological examination showed that there were similar degrees of insulitis in the high and low temperature groups at seven weeks of age. We conclude that environmental temperature can affect the incidence of diabetes in the NOD mouse and that this may be related to alterations in food intake.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00400211
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    MOVEMENT PATTERNS OF RIVERINE LITTER (1997)
    Springer
    Water, air & soil pollution 98 (1997), S. 119-139 
    Details
    ISSN: 1573-2932
    Keywords: litter clearance and accumulation ; riverine litter ; time of travel
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Aspects of litter movement were looked at in a variety of ways. River bank clearances provided valuable information on litter accumulation and movement, showing a distinctive correlation between flood events and litter movement. Introduction of litter outside of channel deposition (diffuse sources) were limited in the study area in South Wales, UK. A rise in litter deposition occurred for some time after flood events, with the main accumulation occurring in the mid-bank zone. As only some litter types have an increased input during flood events e.g. sewage-derived material from combined sewer outfalls (CSO), accumulation of other litter types, e.g. plastic sheeting could be due to their distribution throughout the catchment. A positive correlation between litter stranding and vegetation was found. During high flows, (75.59 cumecs) litter is removed from sites with little restraining vegetation and deposited where stranding potential is high. Smaller items such as feminine hygiene products were more susceptible to stranding than larger plastic sheeting.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026424715108
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Movement patterns of riverine litter (1997)
    Springer
    Water, air & soil pollution 98 (1997), S. 119-139 
    Details
    ISSN: 1573-2932
    Keywords: litter clearance and accumulation ; riverine litter ; time of travel
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Aspects of litter movement were looked at in a variety of ways. River bank clearances provided valuable information on litter accumulation and movement, showing a distinctive correlation between flood events and litter movement. Introduction of litter outside of channel deposition (diffuse sources) were limited in the study area in South Wales, UK. A rise in litter deposition occurred for some time after flood events, with the main accumulation occurring in the mid-bank zone. As only some litter types have an increased input during flood events e.g. sewage-derived material from combined sewer outfalls (CSO), accumulation of other litter types, e.g. plastic sheeting could be due to their distribution throughout the catchment. A positive correlation between litter stranding and vegetation was found. During high flows, (75.59 cumecs) litter is removed from sites with little restraining vegetation and deposited where stranding potential is high. Smaller items such as feminine hygiene products were more susceptible to stranding than larger plastic sheeting.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02128653
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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