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  • 1
    Electronic Resource
    Electronic Resource
    Inner ear damage induced by Mycobacterium fortuitum (1986)
    Springer
    European archives of oto-rhino-laryngology and head & neck 243 (1986), S. 121-125 
    Details
    ISSN: 1434-4726
    Keywords: Bacterial labyrinthitis ; Ultrastructure ; Mycobacterium ; Mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We used electron microscopy to investigate Mycobacterium fortuitum -induced changes in the inner ears of mice. We found that the inner and outer hair cells had degenerated and disappeared in the organ of Corti. Changes in the lower turn of the cochlea were more severe than those of the upper turn while the changes of the outer hair cells were more severe than those of the inner hair cells. Disappearance, fusion and ballooning of the sensory hairs were observed in the vestibular organs. The bacterial extract also induced inner ear damage which was similar to that caused by live M. fortuitum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00453763
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Ultrastructural localization of carbonic anhydrase in the vestibular end organs of the guinea pig (1989)
    Springer
    European archives of oto-rhino-laryngology and head & neck 246 (1989), S. 56-60 
    Details
    ISSN: 1434-4726
    Keywords: Carbonic anhydrase ; Vestibular organ ; Guinea pig ; Histochemistry ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Carbonic anhydrase activity was demonstrated cytochemically on an ultrastructural level in the vestibular end organs of the guinea pig. Reaction product was found in the dark cells, transitional cells, cells of the planum semilunatum and supporting cells. In the dark cells, reaction product was observed in the cytoplasm as well as in the basal infoldings. Reaction product was also observed in the basal infoldings of the transitional cells and the cells of the planum semilunatum. The globular structures inside the supporting cells, transitional cells and the cells of the planum semilunatum were also surrounded by the reaction product. These findings suggest that carbonic anhydrase may have different functions, such as water and ion transport, respiration, nutrition and calcium carbonate deposition in the vestibular end organs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00454136
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Three-dimensional ultrastructure of the endolymphatic sac (1987)
    Springer
    European archives of oto-rhino-laryngology and head & neck 244 (1987), S. 117-122 
    Details
    ISSN: 1434-4726
    Keywords: Endolymphatic sac ; Guinea pig ; Scanning electron microscope ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The subcellular structures of the epithelial cells of the guinea pig endolymphatic sac were studied. By using a newly developed scanning electron microscopy technique, the intracellular organelles could be studied three-dimensionally and the topographic relationships analyzed. The light epithelial cell has an extensive network of endoplasmic reticulum which is characteristically arranged in a basoapical direction. The connections between the inner surface of the plasmalemma and the endoplasmic reticulum were observed, as were connections between the Golgi complex and the endoplasmic reticulum. Our findings support the hypothesis that the endoplasmic reticulum might form transcellular channels through which the cell can transport water and ions from the lumen of the endolymphatic sac out into the subepithelial tissue. The dark epithelial cells seen in particular contained the smooth type of endoplasmic reticulum. Lysosomes were also observed in the dark cells, indicating that these cells probably have more of a secretory function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00458561
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    Paper (German National Licenses)
    Fulltext
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