ISSN:
1432-1041
Schlagwort(e):
spironolactone
;
thiazides
;
digitalis
;
congestive heart failure
;
arterial hypertension
;
skeletal muscle potassium
;
serum potassium
;
skeletal muscle magnesium
;
serum magnesium
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
,
Medizin
Notizen:
Summary The effect of adding spironolactone (Aldactone) on muscle electrolytes was studied in 48 patients with arterial hypertension and/or congestive heart failure who had received conventional diuretic treatment, including a potassium supplement, for more than 1 year. After 6 months on spironolactone 100 mg/day as well as the original conventional diuretic therapy, there was a significant increase in both skeletal muscle potassium and magnesium. At the same time these parameters decreased in the control group. In the spironolactone group there was also a significant increase in the mean serum potassium and creatinine levels. There was a significant fall in blood pressure in the spironolactone-treated group.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00542411
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