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Effect of Acetazolamide (Diamox®) on tear secretion (1985)

Agtmaal, E. J. ; Thörig, L. ; Haeringen, N. J.

Springer

Documenta ophthalmologica 59 (1985), S. 77-80

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ISSN: 1573-2622

Keywords: diuretics ; tear fluid ; peroxidase

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract The side effects of acetazolamide (Diamox®) on lacrimation were measured in rats by means of the cotton-thread tear test. After a daily oral 1-mg dose (administered for five days), comparable to the dose used for adult humans on a drug-to-bodyweight basis, tear production remained unaffected but the lacrimal peroxidase secretion decreased by 60% of the baseline level. After withdrawal of acetazolamide the peroxidase secretion returned to the baseline level.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00162013

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