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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 11 (1977), S. 459-461 
    ISSN: 1432-1041
    Keywords: 16α-gitoxin ; 16-acetyl-16α-gitoxin ; ouabain ; digitoxin ; albumin binding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The binding of semi-synthetic (16α-gitoxin and its 16-acetate) and naturally occurring cardioactive glycosides (digitoxin, ouabain) to human serum albumin was studied using equilibrium dialysis, ultracentrifugation and gel filtration. 16α-gitoxin was 75% bound and its 16-acetate 95%. The percentage binding of digitoxin and ouabain was in good agreement with values reported in literature.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Annals of operations research 16 (1988), S. 1-12 
    ISSN: 1572-9338
    Keywords: Planning systems ; expert systems ; knowledge representation ; inspection plans ; construction plans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Notes: Abstract Traditional O.R. systems are compared with problem solving in Artificial Intelligence via Expert Systems. The discussion centers on explicit knowledge representation. The general aspects are illustrated by two planning systems: · LESP 2: A learning system for inspection plan generation · IDA: A system for finding functions and solutions in construction
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Mathematical methods of operations research 32 (1988), S. 251-269 
    ISSN: 1432-5217
    Keywords: expert systems ; diagnosis ; deep models ; knowledge acquisition ; learning ; temporal representation ; mechanical engineering
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Description / Table of Contents: Zusammenfassung Im gleichen Maße, wie diagnostische Expertensysteme in immer umfangreichere und komplexere Aufgabenstellungen vordringen, zeigt sich, daß ausschließlich regelbasierte, assoziative Ansätze keine angemessene Lösung mehr darstellen. Ein typisches Beispiel für eine solche Situation ist die Diagnose von CNC-Bearbeitungszentren, deren komplexe innere Struktur und die spezifische Vorgehensweise des Experten explizit in der Wissensbasis repräsentiert werden müssen. In diesem Artikel beschreiben wir drei Richtungen, in denen die“konventionelle” Expertensystemarchitektur erweitert werden kann, um den gestiegenen Anforderungen zu entsprechen. Unser System stützt sich auf ein Struktur- und Funktionsmodell des Bearbeitungszentrums, das das in Regelform gespeicherte Wissen ergänzt. Die Verwendung des Modells stellt neuartige Anforderungen an die Wissensakquisition, die durch eine enge Verzahnung mit dem Lernmechanismus des Expertensystems unterstützt wird. Schließlich gehen wir auf die zeitlichen Aspekte der Diagnosesituation ein, die eine spezielle Behandlung der dynamischen Maschinenprozesse und der sich darin entwickelnden Fehler erfordern.
    Notes: Abstract As the domains of diagnostic expert systems become larger and more complex, purely associative approaches are no longer adequate solutions. A good example for such a situation is the diagnosis of a CNC machining center where the diagnostic process has a rich inner structure that has to be reflected in the system. In this article we describe three ways of extending the conventional expert system architecture. Firstly, our system uses a structural model of the machining center in addition to production rules. Secondly, we pay special attention to knowledge acquisition which is intimately related to the learning process. Finally, several temporal aspects of the diagnostic situation are addressed explicitly.
    Type of Medium: Electronic Resource
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