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  • 1
    ISSN: 1573-8221
    Keywords: alloxan diabetes ; heredity ; pancreas
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The body weight and morphometric parameters of the state of the pancreatic insular apparatus (the relative percentage of islet tissue, of A- and B- cells, the number of islets) in fetuses and the adult offspring of healthy female rats and male rats with alloxan diabetes were studied. No change in these parameters was found, indicating that under these conditions the genetic systems of the males are undamaged and that these lesions are not transmitted to the progeny. On the basis of these findings and of the importance of diabetes in the female in the development of insular deficiency in the progeny demonstrated previously, the role of the environment in which the fetus develops in the formation of the diabetes is emphasized.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 451-453 
    ISSN: 1573-8221
    Keywords: human ovum ; fertilization and development in vitro
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A method of cultivating and fertilizing human ova obtained from ovaries removed at operation is described. A special method of sampling active spermatozoa was used for fertilization. Zygote formation was observed 24–36 h after fertilization of the ripe ova, an embryo of the two-cell stage was formed after 36–40 h, and an embryo at the four-cell stage after 48 h. The number of blastomeres reached 8 after 60–64 h, and after approximately 100–120 h the embryos reached the morula stage. The results provide wide scope for the study of the physiology and pathology of early human embryonic development.
    Type of Medium: Electronic Resource
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