ISSN:
1573-3297
Keywords:
escape-avoidance behavior
;
microtubule-associated proteins
;
cortical polysomes
;
synthesisin vitro
;
rats
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Psychology
Notes:
Abstract The cerebral cortices of Sprague-Dawley rats contain polysomal messenger RNA (mRNA) which directs the synthesis of either one or both of two closely related microtubule-associated proteins, A and B. The similarity of these proteins and the absence of rats whose cortices lack polysomal RNA for both A and B (A− B−) are findings that are consistent with the hypothesis that the structural genes for these proteins are allelic. Rats which lack the cortical polysomal mRNA that encodes the A protein perform significantly more poorly in an escape-avoidance paradigm than do rats which possess this mRNA.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01065925
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