ISSN:
1420-9071
Keywords:
Mice
;
glucan treatment
;
Co60-irradiation
;
stem cells, pluripotent
;
granulocytes
;
macrophages
;
erythroid progenitor cells
;
hemopoietic stomal cells
;
hemopoiesis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Glucan, a beta-1, 3 polyglucose, was administered to mice either 1 h before or 1 h after a 650 rad exposure to cobalt-60 radiation. Compared to radiation controls, glucan-treated mice consistantly exhibited a more rapid recovery of pluripotent stem cells and committed granulocyte, macrophage, and erythroid progenitor cells. This may partially explain the mechanism by which glucan also enhances survival in otherwise lethally irradiated mice.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01946654
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