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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Journal of comparative physiology 112 (1976), S. 109-122 
    ISSN: 1432-1351
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Microelectrode recording and computer-based analytical techniques were used to investigate the activity patterns of neurosecretory cells (NSC) in the insect protocerebral neurosecretory system. 1. Although the spike activity of NSC could change with time, three basic type of activity patterns were found, designated silent, regular and irregular. These patterns were detected both centrally and at the release site, the corpus cardiacum. 2. Combining extracellular recording with manipulation of Mg2+ in the neurons' environment, it was established that the NSC activity patterns represent the summed effects of: endogenously-generated activity, synaptic inputs from the central nervous system, and connections between the NSC themselves. 3. Computer-based analytical techniques were used to determine the sources of synaptic input to the NSC. Optic, ocellar, antennal and thoracicoabdominal pathways were found to contribute inputs to NSC.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 39 (1980), S. 411-419 
    ISSN: 1432-1106
    Schlagwort(e): Postnatal development ; Motor cortex ; Kitten
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Average response histograms of the responses of single cortical neurons to imposed forelimb displacements in the kitten were utilized to quantify: (1) Background activity, (2) excitatory response latency, (3) percentage responding neurons, and (4) synaptic effectiveness. Motor cortical neuronal responses to the input did not attain adult values until 55–65 days of age, while adult-like responses were found in somatosensory cortical neurons as early as 9 days postnatally. Motor cortical output to alpha-motoneurons innervating triceps brachii, as tested by intracortical and subcortical microstimulation, first appeared over an interval ranging from 37–45 days postnatally. Thus, motor cortical responses to forelimb mechanoreceptors develop after completion of the output linkages from motor cortex to forelimb motoneurons and, though the motor cortex can output at 45 days, motor cortical functions requiring somatosensory feedback cannot be operative until about 60 days. This system provides a discrete and “late” maturing model in which to study the postnatal development of neuronal networks underlying normal and abnormal motor behavior.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 52 (1983), S. 461-465 
    ISSN: 1432-1106
    Schlagwort(e): Development ; Motoneurons ; Monte Carlo method ; Dendritic diameter
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A Monte Carlo method was used to quantitate the dendritic characteristics of horseradish peroxidase-injected lumbar motoneurons (MNs) from kittens 44 to 73 days old (during the postnatal interval when motor cortical input/output linkages mature) and compared with those from adults. All of the 6 MNs analyzed were within the same range of somal sizes (40–61 μm) and dendritic domain volumes. However, two-dimensional distributions of dendritic diameter versus distance from the soma revealed that in the youngest MNs' (44 and 51 days) most dendritic processes (82 and 84%) were less than 2 μm in diameter, and had no dendrites greater than 5 μm. The adult MNs had large dendrites (20 and 24% were greater than 5 μ), while the kittens of intermediate age (66 and 73 days) exhibited both adult-like (6 and 13% greater than 5 μm) and immature (48 and 73% less than 2 μm) characteristics. “Hit probabilities” calculated from the Monte Carlo data suggest that immature MNs's dendrites may present denser targets per unit volume for ingrowing growth cones than adult MNs, and may facilitate the probability of contact with appropriate afferent axons.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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