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  • 1
    Digitale Medien
    Digitale Medien
    Brain Metabolism and Intracellular pH During Ischaemia and Hypoxia: An In Vivo 31P and 1H Nuclear Magnetic Resonance Study in the Lamb (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 49 (1987), S. 0 
    Details
    ISSN: 1471-4159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Abstract: Brain metabolism and intracellular pH were studied during and after episodes of ischaemia and hypoxia-ischaemia in lambs anaesthetised with sodium pentobarbitone. 31P and 1H magnetic resonance spectroscopy methods were used to monitor brain pHi and brain concentrations of Pi, phosphocreatine (PCr), β-nucleoside triphosphate (βNTP), and lactate. Simultaneous measurements were made of cerebral blood flow and cerebral oxygen and glucose consumption. Cerebral ischaemia sufficient to reduce oxygen delivery to 75% of control values was associated with a fall in brain pHi and increase in brain Pi. Progressively severe hypoxia-ischaemia was associated with a progressive fall in brain pHi, PCr, and βNTP and increase in brain pi In two animals the increase in brain lactate during hypoxia-ischaemia measured by 1H nuclear magnetic resonance (NMR) could be quantitatively accounted for by the increased net uptake of glucose by the brain in relation to oxygen, but was insufficient to account for the concomitant aci-dosis according to previous estimates of brain buffering capacity. In four animals brain pHi, PCr, pi, and βNTP had returned to normal 1 h after the hypoxic-ischaemic episode. In one animal brain pHi had reverted to normal at a time when 1H NMR indicated persistent elevation of brain lactate.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1471-4159.1987.tb03396.x
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  • 2
    Digitale Medien
    Digitale Medien
    Some effects of herbage composition, as influenced by previous grazing management, on milk production by cows grazing on ryegrass/white clover pastures. 1. Milk production in early spring: effects of different regrowth intervals during the preceding winter period (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Grass and forage science 47 (1992), S. 0 
    Details
    ISSN: 1365-2494
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Two experiments (1a and 1b) were carried out to examine the effects of differences in pre-grazing herbage mass and composition on milk production by cows grazing in early spring. Swards with high (5 · 1t DM ha−1) or low (2 · 9 t DM ha-1) pre-grazing masses in early spring were created by either long or short periods of regrowth during the preceding winter.The low-mass swards contained lower concentrations of grass stem and senescent material, but higher concentrations of clover, than the high-mass swards. Herbage from the low-mass swards was also more digestible.Cows were offered common daily herbage allowances from both swards (26 and 22 kg DM cow−1 in Experiments la and lb respectively). The cows grazing on the low-mass swards produced significantly greater yields of milk, milk fat and milk protein.The results show that herbage from the lowmass swards was of higher feeding value for lactating cows in early lactation. The practical implications for milk production per cow and per hectare are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2494.1992.tb02276.x
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  • 3
    Digitale Medien
    Digitale Medien
    Some effects of herbage composition, as influenced by previous grazing management, on milk production by cows grazing on ryegrass/white clover pastures. 2. Milk production in late spring/summer: effects of grazing intensity during the preceding spring period (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Grass and forage science 47 (1992), S. 0 
    Details
    ISSN: 1365-2494
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Three experiments (2a, 2b and 2c) were carried out to examine the effects of different grazing intensities imposed during spring on subsequent herbage composition and milk production measured in summer.Increased intensity of grazing imposed during spring (including the period of reproductive development in ryegrasses) produced swards in early summer with lower pre-grazing herbage masses, which contained higher concentrations of green leaf, clover and digestible nutrients, but lower concentrations of grass stem and senescent material.In the first and second experiment cows were given a common daily allowance of total herbage dry matter (DM). The cows grazing on low-mass swards in early summer produced larger daily yields of milk, fat and protein than those grazing on the high-mass swards.In the third experiment, cows were given a common daily allowance of green leaf DM from three swards which differed in pre-grazing herbage mass and in herbage composition. The allowances of total DM required differed widely between the treatments. There were no significant differences in milk yields between the swards despite the large differences in herbage composition.The practical implications of these results are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2494.1992.tb02277.x
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  • 4
    Digitale Medien
    Digitale Medien
    Erythema gyratum repens and acquired ichthyosis associated with transitional cell carcinoma of the kidney (2001)
    Oxford, UK : Blackwell Science Ltd
    Clinical and experimental dermatology 26 (2001), S. 0 
    Details
    ISSN: 1365-2230
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Both erythema gyratum repens (EGR) and acquired ichthyosis are distinctive dermatoses which have strong associations with internal malignancy. EGR usually precedes the diagnosis of malignancy whereas acquired ichthyosis commonly manifests after the detection of malignancy. We report a patient who initially presented with a figurate eruption of EGR which later developed into a widespread ichthyosis with disappearance of the serpiginous rash. Further investigations revealed an underlying transitional cell carcinoma of the kidney, an association which has not previously been reported with either EGR or acquired ichthyosis. The occurrence of two paraneoplastic skin disorders in the same patient may be explained by tumour cell secretion of transforming growth factor alpha, which has been shown to be mitogenic for keratinocytes.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1365-2230.2001.00879.x
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  • 5
    Digitale Medien
    Digitale Medien
    Effect of plant age and severity of defoliation on regrowth of sheep's burnet during substrate moisture depletion (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Grass and forage science 49 (1994), S. 0 
    Details
    ISSN: 1365-2494
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Regrowth of 3- and 4-month old (‘young’ and ‘old’ respectively) sheep's burnet [Sanguisorba minor ssp. muricata (Spach) Briq.] was studied under limiting and non-limiting moisture conditions in a glasshouse. Moisture deficits were imposed by using a single cycle of withholding moisture until first wilting. Plants of each age were defoliated severely at three levels which represented approximately 80–100% canopy removal. These levels were based on the proportion retained of the eight most mature leaves on each plant and were referred to as complete [0% residual leaf area (rLA)] and partial [50% rLA (four leaves) and 100% rLA (eight leaves)] defoliation. Vegetative growth and total non-structural carbohydrate (TNC) levels were studied.Leaf number (0-8 leaves), area (0-115 cm2) and dry weight (0-1·0 g) differed (P 〈 0·05) between defoliation intensities at the start of regrowth, while stubble (1·2 g) and root (12.·6 g) dry weights were similar. Soluble sugars [〈 6% dry matter (DM)] and starch (〈 1% DM) occurred in leaf, stubble and root. Old plants were morphologically and physiologically more developed than young plants. For example, stubble (2·0 g) and root (21·5 g) dry weights of old plants were greater (P 〈 0·05) than those of young plants (04 and 3·7 g respectively).Defoliation intensity had a major effect on regrowth, with completely defoliated plants at the final harvest having leaf numbers (forty-nine leaves) and areas (235 cm2) almost twice those of partially defoliated plants. Stubble soluble sugar levels (38% DM) were lower than those of partially defoliated plants (5·5% DM), and it was suggested that these contributed to regrowth. Moisture regime had a negligible influence on plant growth. However, plants in the dry regime had soluble sugar levels 1·4 (stubble) -1·7 (roots) times higher than those watered adequately, which suggested that plants adjusted to the water depletion. The effects of plant age on regrowth were similar for most characters, but the larger and physiologically more mature old plants would probably be more tolerant of successive defoliations.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2494.1994.tb02008.x
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  • 6
    Digitale Medien
    Digitale Medien
    Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris (2000)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 142 (2000), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: In this study we have evaluated the use of blue light (peak at 415 nm) and a mixed blue and red light (peaks at 415 and 660 nm) in the treatment of acne vulgaris. One hundred and seven patients with mild to moderate acne vulgaris were randomized into four treatment groups: blue light, mixed blue and red light, cool white light and 5% benzoyl peroxide cream. Subjects in the phototherapy groups used portable light sources and irradiation was carried out daily for 15 min. Comparative assessment between the three light sources was made in an observer-blinded fashion, but this could not be achieved for the use of benzoyl peroxide. Assessments were performed every 4 weeks. After 12 weeks of active treatment a mean improvement of 76% (95% confidence interval 66–87) in inflammatory lesions was achieved by the combined blue–red light phototherapy; this was significantly superior to that achieved by blue light (at weeks 4 and 8 but not week 12), benzoyl peroxide (at weeks 8 and 12) or white light (at each assessment). The final mean improvement in comedones by using blue–red light was 58% (95% confidence interval 45–71), again better than that achieved by the other active treatments used, although the differences did not reach significant levels. We have found that phototherapy with mixed blue–red light, probably by combining antibacterial and anti-inflammatory action, is an effective means of treating acne vulgaris of mild to moderate severity, with no significant short-term adverse effects.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1365-2133.2000.03481.x
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  • 7
    Digitale Medien
    Digitale Medien
    An ultrastructural study of the mononuclear cell infiltrate of mycosis fungoides and poikiloderma atrophicans vasculare (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 7 (1982), S. 0 
    Details
    ISSN: 1365-2230
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Tissue from twenty-five patients with mycosis fungoides and three patients with poikiloderma atrophicans vasculare was examined ultrastructurally. Characteristic abnormal lymphoid cells were conspicuous in all biopsies comprising 30–60% of the cutaneous infiltrate. These cells possessed irregular nuclear outlines presenting a spectrum from mild indentation to grossly cerebriform shapes. The other prominent cell type was the histiocyte which occasionally appeared abnormal. Bizarre histiocytic cells resembling the interdigitating reticulum cell of lymph node T cell areas were also observed. In the epidermal infiltrate, abnormal lymphoid cells were seen singly infiltrating between keratinocytes and less frequently in groups, forming Pautrier microabscesses, or in close apposition to histiocytes. Langerhans cells appeared in normal numbers and were usually isolated but were occasionally seen in contact with lymphoid cells.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2230.1982.tb02380.x
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  • 8
    Digitale Medien
    Digitale Medien
    Optical properties of ZnSe1−xSx epilayers grown on misoriented GaAs substrates (1998)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 84 (1998), S. 2245-2250 
    Details
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: The strain induced heavy hole and light hole exciton splitting of ZnSe1−xSx (x〈0.1) epilayers grown on misoriented GaAs (001) substrates has been studied by reflectance spectroscopy. The heavy hole and light hole exciton energies are determined by the composition of the layers. It was concluded that for both thin (largely unrelaxed strain) and thick epilayers (with largely relaxed strain) misorientation of the substrate results in increase of x, i.e., in increasing incorporation of sulphur. However, the additional strain expected due to the increasing incorporation of sulphur with misorientation was not observed due to partial strain relief of the epilayers grown on misoriented substrates. The optical quality of the epilayers is tilt angle dependent and is best for about 10° tilt from the (001) direction. © 1998 American Institute of Physics.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.368360
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  • 9
    Digitale Medien
    Digitale Medien
    The inter-relationship between isotretinoin/acne and depression (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 12 (1999), S. 0 
    Details
    ISSN: 1468-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1468-3083.1999.tb01042.x
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  • 10
    Digitale Medien
    Digitale Medien
    Using neutral metastable argon atoms and contamination lithography to form nanostructures in silicon, silicon dioxide, and gold (1996)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 69 (1996), S. 2773-2775 
    Details
    ISSN: 1077-3118
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: This letter describes the fabrication of ∼80 nm structures in silicon, silicon dioxide, and gold substrates by exposing the substrates to a beam of metastable argon atoms in the presence of dilute vapors of trimethylpentaphenyltrisiloxane, the dominant constituent of diffusion pump oil used in these experiments. The atoms release their internal energy upon contacting the siloxanes physisorbed on the surface of the substrate, and this release causes the formation of a carbon-based resist. The atomic beam was patterned by a silicon nitride membrane, and the pattern formed in the resist material was transferred to the substrates by chemical etching. Simultaneous exposure of large areas (44 cm2) was also demonstrated. © 1996 American Institute of Physics.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.117671
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