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  • 1
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Tissue inhibitor of metalloproteinases (TIMP)-2 is a highly conserved molecule, which binds both active and latent matrix metalloproteinase (MMP)-2. TIMP-2 is also involved in the activation of MMP-2 on the cell surface. A quantitative enzyme-linked immunosorbent assay (ELISA) was established and optimized for measurement of TIMP-2 in plasma. The capturing antibody in the ELISA was a monoclonal, while the detecting antibody was a chicken polyclonal antibody recognizing the native form of human TIMP-2. The levels of TIMP-2 were measured in ethylenediaminetetraacetic acid (EDTA) and citrate plasma from healthy donors. The median values were determined as 163 ng/ml (n = 186) with a range of 109–253 ng/ml for EDTA plasma and 139 ng/ml (n = 77) with a range of 95–223 ng/ml for citrate plasma. The TIMP-2 concentration in citrate plasma from 15 patients with advanced, stage IV breast cancer had a median value of 160 ng/ml, only slightly higher but statistically distinguishable from the level found in citrate plasma from the healthy donors. In addition, the TIMP-2 concentration in EDTA plasma from colorectal cancer patients revealed a significantly higher level in plasma from patients with Dukes stage A (P = 0.01) compared with patients with more advanced Dukes stages.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Abdominal imaging 9 (1984), S. 341-343 
    ISSN: 1432-0509
    Schlagwort(e): Gallbladder, anomalies ; Suprahepatic gallbladder
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The authors report a case of suprahepatic gallbladder associated with hepatomegaly. The ectopic gallbladder was visualized by sonography, computed tomography, and endoscopic retrograde cholangiography.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Abdominal imaging 9 (1984), S. 335-339 
    ISSN: 1432-0509
    Schlagwort(e): Bile ducts, ultrasound studies ; Bile ducts, prosthesis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Biliary drainage by endoprosthesis, inserted either transcutaneously or endoscopically, is as effective and better supported than percutaneous drainage, but harder to control. Forty-four patients with biliary or pancreatic carcinoma treated by endoprostheses were followed up by ultrasound. Sonography was effective in the demonstration of the drainage effectiveness and the detection of prosthetic dysfunction or eventual complications. Consequently, it may be considered a valuable method to complement the biochemical tests in the monitoring of endoprostheses.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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