Bibliothek

X
feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
  • 1
    Digitale Medien
    Digitale Medien
    Gamma-Poly(glutamic acid)/Chitosan Composite Scaffolds for Tissue Engineering Applications (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 539-543 (Mar. 2007), p. 567-572 
    Details
    ISSN: 1662-9752
    Quelle: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Thema: Maschinenbau
    Notizen: The development of tissue engineering provides a novel approach to restore bodilyfunctions by seeding cells onto various scaffolds. Although chitosan is a non-toxic biomaterial, itscytocompatibility still needs to be improved. In this study, gamma-poly(glutamic acid) (γ-PGA) wasblended with chitosan to prepare both dense and porous γ-PGA/chitosan composite scaffolds usingthe freeze-gelation method. This method saves time and energy, and there is less residual solvent.SEM micrographs demonstrated that an interconnected porous structure with a pore size of 30-100micrometer was present in the scaffolds. The hydrophilicity of the scaffolds was significantlyimproved by γ-PGA. Further, the tensile strength of the porous γ-PGA-modified chitosan scaffoldswas about 50% higher than that of the unmodified chitosan scaffolds. The number of osteosarcomacells cultured on the γ-PGA-modified scaffolds was about double that on the unmodified chitosanscaffolds on day 7. Thus, the γ-PGA/chitosan composite scaffolds, due to their better hydrophilicity,cytocompatibility, and mechanical strength, are very promising biomaterials for tissue engineeringapplications. We further demonstrated the use of glutamic acid to enhance the tensile strength ofchitosan-based composite porous scaffolds. The tensile strength of the chitosan/collagen compositescaffolds was increased by more than 2 times with the addition of glutamic acids as cross-linkingbridges. We found that the hepatocytes attached and proliferated well on these composite scaffolds,demonstrating that the glutamic acid modified-chitosan composite scaffolds are also potential tissueengineering biomaterials
    Materialart: Digitale Medien
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/14/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.539-543.567.pdf
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 2
    Digitale Medien
    Digitale Medien
    Construction of ternary phase diagrams in nonsolvent/solvent/PMMA systems (1998)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 36 (1998), S. 607-615 
    Details
    ISSN: 0887-6266
    Schlagwort(e): ternary phase diagram ; binodal curve ; Flory-Huggins theory ; interaction parameter ; membrane formation ; Physics ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Physik
    Notizen: In this work, the ternary phase diagrams in three nonsolvent/solvent/PMMA systems (n-hexane/n-butyl acetate/PMMA, water/acetone/PMMA, and n-hexane/acetone/PMMA) were constructed by theoretical calculation and experimental measurement. Binodal curves were calculated by using the Flory-Huggins theory for three-component systems and measured by titrating the PMMA solution with nonsolvent until the onset of turbidity. By using concentration-dependent nonsolvent/solvent and solvent/PMMA interaction parameters and constant nonsolvent/PMMA interaction parameters, good agreement has been obtained between the calculation and the measurement. The values of nonsolvent/solvent interaction parameters were taken from the literature sources, and the values of solvent/PMMA and nonsolvent/PMMA interaction parameters were measured by vapor sorption and swelling equilibrium, respectively. © 1998 John Wiley & Sons, Inc. J Polym Sci B: Polym Phys 36: 607-615, 1998
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...