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  • 1980-1984  (3)
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  • 1
    Digitale Medien
    Digitale Medien
    Differences in the distribution of methyl mercury in erythrocytes, plasma, and brain of Japanese quails and rats after a single oral dose (1984)
    Springer
    Archives of toxicology 56 (1984), S. 132-135 
    Details
    ISSN: 1432-0738
    Schlagwort(e): Methyl mercury ; Toxicokinetics ; Differential toxicity ; Japanese quail ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Distribution of a single oral dose of methyl mercury (10 mg Hg/kg body weight) was followed from 90 min up to 120 h in plasma, erythrocytes, and brain of Japanese quails and rats. Significantly higher Hg concentrations were observed in plasma and brain of quails and red blood cells of rats. Blood/brain ratio decreased in quails from 6 to 2 at 24 h and 120 h respectively, whereas it increased in rats. Erythrocyte/plasma ratio in quails was about three times lower and averaged 54. The differences in Hg distribution were accompanied by a more than 3-fold higher acute toxicity in quails under adequate experimental conditions.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00349086
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  • 2
    Digitale Medien
    Digitale Medien
    Effect of water pollutants and other chemicals upon the activity of lipasein vitro (1981)
    Springer
    Archives of environmental contamination and toxicology 10 (1981), S. 357-363 
    Details
    ISSN: 1432-0703
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Energietechnik , Medizin
    Notizen: Abstract Lipase preparations were treatedin vitro with 100 chemicals of various classes, many of which are environmental pollutants, to determine their effect upon enzyme activity. The greatest inhibition was caused by mercuric ion and certain heavy metal cations; almost as inhibiting were pentachlorophenol, dicofol, 2,4,5-trichlorophenol, and DDT. Less inhibition was found with other inorganic salts, organo-metals, other organic chemicals, and some pesticides. Apart from dichromate ion, the anions studied had a low to negligible effect on lipase. A mixture of 10 inorganic salts had an approximately cumulative inhibitory effect on enzyme activity. None of the chemicals studied caused a measurable activation of the enzyme.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01055637
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  • 3
    Digitale Medien
    Digitale Medien
    Cefotaxime concentrations in prostatic tissue (1983)
    Springer
    Infection 11 (1983), S. 33-34 
    Details
    ISSN: 1439-0973
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Die Cefotaxim-Konzentration in Prostata-Adenom-Gewebe nach Injektion von 2 g i.v. wurde gemessen. Bei den Bestimmungen wurde der Blutgehalt in den Gewebeproben berücksichtigt. Die Unterschiede zwischen den vorliegenden Ergebnissen und solchen, die von anderen Gruppen publiziert wurden, werden diskutiert.
    Notizen: Summary Cefotaxime concentrations were determined in samples of prostatic adenomas following a 2 g i.v. injection. The level of blood contamination in the samples was taken into consideration when determinations were made. Differences between our results and those published by other groups are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01651355
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