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Digitale Medien

Kinin generation following methacholine nasal airway challenge of non-allergic subjects (1992)

Baumgarten, C. R. ; Niemz, W. ; Kunkel, G.

Springer

European archives of oto-rhino-laryngology and head & neck 249 (1992), S. 318-321

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ISSN: 1434-4726

Schlagwort(e): Chronic non-allergic rhinitis ; Kinins ; Methacholine challenge ; Muscarinic receptor stimulation

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Following nasal challenges with the muscarinic neurotransmitter methacholine in 14 patients with chronic non-allergic rhinitis, kinin generation was induced. This occurrence was inhibited by pretreatment with anticholinergic agents (ipratropium bromide) and by an overdose of neurotransmitter, indicating that a muscarinic receptor is stimulating the liberation of kinin. These observations suggest that patients with chronic non-allergic rhinitis exhibit cholinergic neurotransmitter-induced kinin generation.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00179380

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