ISSN:
1432-2013
Schlagwort(e):
Deiters Neurones
;
Mossy Fibre Afferents
;
Climbing Fibre Afferents
;
Purkinje Cell Inhibition
;
Harmaline
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Summary Intracellular records from 203 neurones located in Deiter's nucleus were evaluated in respect to IPSPs evoked by stimulation of the spinal cord. In 85% of the cells, short latency IPSPs were observed (less than 4.5 ms from C2-level), attributable to fast conducting pathways. The majority of them (3–4.5 ms) includes activity transmitted via the cerebellar cortex, while latencies between 1.0 and 2.9 ms as observed for roughly 10% of the early IPSPs, are too short to include cerebellum. IPSPs with longer latencies (mean 7.3 ms from C2-level) were found in 75% of the cells. Low conduction velocity of their spinal pathways and other criteria suggest that spino-olivo-climbing fibre systems including the cerebellar cortex are involved. The latter type of IPSP often shows a complex configuration, expainable by reflex discharges of olivary neurones and disinhibitory phenomena coupled to climbing fibre activation. Clean, rhythmic IPSPs were seen after injection of harmaline.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00587837
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