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Digitale Medien

Hypereosinophilic syndrome in Hodgkin's disease with increased granulocyte-macrophage colony-stimulating factor (1995)

Endo, M. ; Usuki, K. ; Kitazume, K. ; [weitere]

Springer

Annals of hematology 71 (1995), S. 313-314

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ISSN: 1432-0584

Schlagwort(e): Hodgkin's disease ; IL-5 ; GM-CSF ; Eosinophilia

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract We report a patient with eosinophilia accompanied by Hodgkin's disease who showed remarkable increase in granulocyte-macrophage colony-stimulating factor (GM-CSF) in plasma but no increase in interleukin-5 (IL-5). The plasma GM-CSF level normalized as eosinophilia and lymphadenopathy disappeared after chemotherapy. Immunohistochemical study with immunoperoxidase staining technique showed a positive stain in lymph node cells by monoclonal anti-GM-CSF antibody. Eosinophilia is often accompanied by Hodgkin's disease, and several cases have been reported to show high levels of plasma IL-5. To our knowledge, this is the first report to show a high level of plasma GM-CSF in Hodgkin's disease with eosinophilia.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01697986

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