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Digitale Medien

Fulminant falciparum malaria (1990)

Smit, W. M. ; Oudemans-van Straaten, H. M. ; Zandstra, D. F.

Springer

Intensive care medicine 16 (1990), S. 517-519

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Details

ISSN: 1432-1238

Schlagwort(e): Malaria ; Exchange transfusion ; Tumour necrosis factor ; Corticosteroids

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract A case of fulminant falciparum malaria with a 35% parasitaemia, shock and subcoma was treated successfully by using parenteral chemotherapy, exchange transfusion, dexamethasone, circulatory support and mechanical ventilation. Pathophysiology and complications of falciparum malaria are discussed. The treatment of severe malaria should aim for a fast reduction in parasitaemia and toxic products. An exchange transfusion can be additive to parenteral chemotherapy. Blocking the over-reacting cell-mediated immune response, aggressive shock treatment, prevention of secondary infections and maintaining normoglycaemia might reduce morbidity and mortality of fulminant falciparum malaria.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01709404

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