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Digitale Medien

Large cell anaplastic lymphoma: Evaluation of immunophenotype on paraffin and frozen sections in comparison with ultrastructural features (1991)

Hansmann, M. -L. ; Fellbaum, C. ; Bohm, A.

Springer

Virchows Archiv 418 (1991), S. 427-433

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Details

ISSN: 1432-2307

Schlagwort(e): Large cell anaplastic lymphoma ; Electron microscopy ; Immunophenotyping

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Eleven cases of large cell anaplastic lymphoma (T typen=5, B typen=4, 0 typen=2) were investigated using electron microscopy and immunophenotyping on formalin-fixed paraffin sections and frozen sections of fresh tissue, to determine whether morphological criteria exist for the discrimination of T, B, and 0 phenotypes. Tumour cell lineage could not be established from ultrastructural features. On paraffin material monoclonal B-cell markers Ki-B5 and L-26 served as reliable tools for recognizing the B phenotype of large cell anaplastic lymphomas (previously determined on fresh material), whereas monoclonal antibodies MT1 (CD43) and UCHL1 (CD45RO) were of limited value in lineage determination.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01605929

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