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  • 2005-2009  (26)
  • 11
    Electronic Resource
    Electronic Resource
    Beyond attachment theory and therapy: Towards sensitive and evidence-based interventions with foster and adoptive families in distress (2005)
    Oxford, UK : Blackwell Science Ltd
    Child & family social work 10 (2005), S. 0 
    Details
    ISSN: 1365-2206
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Sociology
    Notes: Elements of attachment theory have been embraced by practitioners endeavouring to assist foster and adopted children and their parents. Attachment theory articulates the potential risks of experiencing multiple caregivers; emphasizes the importance of close social relationships to development; and recognizes that substitute parents may not always have close relationships with children who have experienced adversities before joining them. Attachment theory offers concerned parents what they believe to be a scientific explanation about their lack of the close, satisfying parent–child relationship they desire. Yet the scientific base of attachment theory is limited both in terms of its ability to predict future behaviours, and especially with regard to its use as the underpinning theory for therapeutic intervention with children experiencing conduct problems. There is a critical need to review the role of attachment theory in child and family services and to consider its place among other explanations for children's disturbing behaviour. An important step towards pursuing alternative approaches is for researchers and practitioners to understand the reasons the attachment paradigm appeals to so many adoptive and foster parents, given the apparent widespread prevalence of attachment-based interventions. Such understanding might assist in the development of adoption-sensitive uses of appropriate evidence-based treatment approaches.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2206.2005.00380.x
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  • 12
    Electronic Resource
    Electronic Resource
    Hindmarsh, D. Bruce: The Evangelical Conversion Narrative: Spiritual Autobiography in Early Modern England : Oxford, Oxford University Press, 2005 (2006)
    New York : Cambridge University Press
    Church history 75 (2006), S. 918-920 
    Details
    ISSN: 0009-6407
    Source: Cambridge Journals Digital Archives
    Topics: History , Theology and Religious Studies
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S0009640700112053
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  • 13
    Electronic Resource
    Electronic Resource
    Rubisco specificity factor tends to be larger in plant species from drier habitats and in species with persistent leaves (2005)
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 28 (2005), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The specificity factor of Rubisco is a measure of the relative capacities of the enzyme to catalyse carboxylation and oxygenation of ribulose 1,5-bisphosphate and hence to control the relative rates of photosynthetic carbon assimilation and photorespiration. Specificity factors of purified Rubisco from 24 species of C3 plants found in diverse habitats with a wide range of environmental growth limitations by both water availability and temperature in the Balearic Islands were measured at 25 °C. The results suggest that specificity factors are more dependent on environmental pressure than on phylogenetic factors. Irrespective of phylogenetic relationships, higher specificity factors were found in species characteristically growing in dryer environments and in species that are hemideciduous or evergreen. Effects of temperature on specificity factor of the purified enzyme from 14 species were consistent with the concept that higher specificity factors were associated with an increase in the activation energy for oxygenation compared to carboxylation of the 2,3-enediolate of RuBP to the respective transition state intermediates. The results are discussed in terms of selection pressures leading to the differences in specificity factors and the value of the observations for identifying useful genetic manipulation to change Rubisco polypeptide subunits.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3040.2005.01300.x
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  • 14
    Electronic Resource
    Electronic Resource
    Concerning invasive species: Reply to Brown and Sax (2005)
    Melbourne, Australia : Blackwell Science Pty
    Austral ecology 30 (2005), S. 0 
    Details
    ISSN: 1442-9993
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract  Biological invasions have commonly occurred, and to a lesser degree continue to do so, without human assistance. It is, however, a combination of the rate and magnitude, as well as the distances and agency involved, that separates human-driven invasion processes from self-perpetuated colonization events. Exotic species are a pervasive and major component of human-induced global change. Decisions to manage invasive species will require judgements to be communicated from scientists to policy makers, because scientists may often be the only ones in the position to make them.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1442-9993.2005.01505.x
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  • 15
    Electronic Resource
    Electronic Resource
    Routine oral examination: differences in characteristics of Dutch general dental practitioners related to type of recall interval (2005)
    Oxford, UK : Munksgaard International Publishers
    Community dentistry and oral epidemiology 33 (2005), S. 0 
    Details
    ISSN: 1600-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract –  Objectives:  The aim of this study was to explore differences in behaviour (characteristics and opinions) among general dental practitioners (GDPs), using either a fixed (Fx) or an individualized recall interval (Iv) between successive routine oral examinations (ROEs).Methods:  In the year 2000, data were collected by means of a written questionnaire sent to a random stratified sample of 610 dentists of whom 521 responded, of which 508 (83%) were used for analysis.Results:  Two groups of GDPs were distinguished based on their answer to the question: ‘Do you apply for all patients a fixed recall interval between two successive ROEs?’ Fifty-one per cent of the GDPs (n = 257) applied Fxs for all patients, generally for a period of 6 months. Ivs were applied by 49% (n = 251) of GDPs, depending on the determination of specific patient characteristics. Logistic regression analysis showed that GDPs applying Fxs also used fixed periods between successive bitewing radiographs for all patients. Furthermore, dentists applying Ivs required more time to conduct an ROE, partly because of a more extensive periodontal screening. GDPs applying Fxs, adhered more to the opinion that a fixed recall regime (every 6 months, as existed before 1995) should be re-introduced, whereas the GDPs in support of Ivs were more in favour to support the opinion that the ROE is ‘an excellent instrument for effective, individualized oral care’.Conclusions:  Dutch GDPs differ in the way they deal with the determination of recall interval frequency. These are also specific differences in performance and opinions regarding ROE. With the changing prevalence of oral diseases and the skewed distribution within populations, further research is advocated on consistent decision making to determine the most appropriate recall policy in preventing oral disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0528.2005.00221.x
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  • 16
    Electronic Resource
    Electronic Resource
    Antibiotic-induced SOS response promotes horizontal dissemination of pathogenicity island-encoded virulence factors in staphylococci (2005)
    Oxford, UK : Blackwell Science Ltd
    Molecular microbiology 56 (2005), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Although mobile genetic elements have a crucial role in spreading pathogenicity-determining genes among bacterial populations, environmental and genetic factors involved in the horizontal transfer of these genes are largely unknown. Here we show that SaPIbov1, a Staphylococcus aureus pathogenicity island that belongs to the growing family of these elements that are found in many strains, is induced to excise and replicate after SOS induction of at least three different temperate phages, 80α, φ11 and φ147, and is then packaged into phage-like particles and transferred at high frequency. SOS induction by commonly used fluoroquinolone antibiotics, such as ciprofloxacin, also results in replication and high-frequency transfer of this element, as well as of SaPI1, the prototypical island of S. aureus, suggesting that such antibiotics may have the unintended consequence of promoting the spread of bacterial virulence factors. Although the strains containing these prophages do not normally contain SaPIs, we have found that RF122-1, the original SaPIbov1-containing clinical isolate, contains a putative second pathogenicity island that is replicated after SOS induction, by antibiotic treatment, of the prophage(s) present in the strain. Although SaPIbov1 is not induced to replicate after SOS induction in this strain, it is transferred by the antibiotic-activated phages. We conclude that SOS induction by therapeutic agents can promote the spread of staphylococcal virulence genes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.2005.04584.x
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  • 17
    Electronic Resource
    Electronic Resource
    Spirochetes at the forefront of periodontal infections (2005)
    Oxford, UK : Munksgaard International Publishers
    Periodontology 2000 38 (2005), S. 0 
    Details
    ISSN: 1600-0757
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0757.2005.00108.x
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  • 18
    Electronic Resource
    Electronic Resource
    Expression of human β-defensin-3 in gingival epithelia (2005)
    Oxford, UK : Munksgaard International Publishers
    Journal of periodontal research 40 (2005), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective:  This study aimed to investigate the expression patterns of the newly discovered human β-defensin-3 (hBD-3) in human gingiva.Background:  Human β-defensins (hBDs) are a group of small, broad-spectrum, cationic antimicrobial peptides. Our recent study showed that the expression levels of hBD-1 and 2 peptides were associated with periodontal conditions.Methods:  A total of 49 gingival biopsies were collected, including 33 samples from 21 patients with chronic periodontitis and 16 samples from 16 periodontally healthy subjects. The expression of hBD-3 was detected by immunohistochemistry and in situ hybridization. Double staining was undertaken to identify hBD-3 peptide-positive cells, using CD-1a and cytokeratin 20 as markers for Langerhans cells and Merkel cells, respectively.Results:  hBD-3 peptide was detected in 88% of the samples, which was confined to the gingival epithelia. In healthy control subjects, hBD-3 peptide was more frequently detected in the basal layer as compared to the patients (53% vs. 18%, p 〈 0.05). In patients, hBD-3 expression extended from the basal layer to the spinous layers (82%), in which hBD-3 was confined to the basal and deep spinous layers in clinically healthy tissues from patients, whereas it extended to the superficial spinous layers in pocket tissues from patients (0% vs. 50%, p 〈 0.05). In both groups, hBD-3 peptide was expressed not only in gingival keratinocytes, but also in Langerhans cells and Merkel cells. hBD-3 transcripts were detected in 90% of the samples and they were confined to the basal and/or suprabasal layers of gingival epithelia.Conclusions:  This study shows that hBD-3 is frequently expressed in gingival epithelia. The appropriate expression of hBD-3 peptide may contribute to the maintenance of periodontal homeostasis, possibly through its antimicrobial effect and promotion of adaptive immune responses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.2005.00827.x
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  • 19
    Electronic Resource
    Electronic Resource
    Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia (2006)
    [s.l.] : Nature Publishing Group
    Nature genetics 38 (2006), S. 214-217 
    Details
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Whole-genome association studies are predicted to be especially powerful in isolated populations owing to increased linkage disequilibrium (LD) and decreased allelic diversity, but this possibility has not been empirically tested. We compared genome-wide data on 113,240 SNPs typed on 30 trios from ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/ng1712
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  • 20
    Electronic Resource
    Electronic Resource
    Idiosyncratic tuning of tRNAs to achieve uniform ribosome binding (2005)
    [s.l.] : Nature Publishing Group
    Nature structural & molecular biology 12 (2005), S. 788-793 
    Details
    ISSN: 1545-9985
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The binding of seven tRNA anticodons to their complementary codons on Escherichia coli ribosomes was substantially impaired, as compared with the binding of their natural tRNAs, when they were transplanted into tRNA2Ala. An analysis of chimeras composed of tRNA2Ala and various amounts of either ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nsmb978
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