Bibliothek

X
feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
Filter
  • 1990-1994  (7)
  • 1985-1989  (12)
  • 1980-1984  (4)
  • 1965-1969  (1)
  • 1960-1964  (1)
  • 11
    Digitale Medien
    Digitale Medien
    Lipid peroxidation caused by chinoform-ferric chelate in cultured neural retinal cells (1985)
    Springer
    Cellular and molecular life sciences 41 (1985), S. 1561-1563 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Lipid peroxidation ; chinoform-ferric chelate ; chick neural retinal cells
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Incorporation of chinoform-ferric chelate was demonstrable in cultured neural retinal cells of chick embryos after 1 h of incubation, and the lipid peroxide level in the cells was increased strikingly 1 h thereafter. On the other hand, free ferric ions were scarcely incorporated into the cells, and a significant increase in the lipid peroxide level in the cells was not observed. These data indicate that chinoform is carrier of iron for its passage through cell membranes and that the incorporated iron induces lipid peroxidation which in turn leads to neural cell degeneration.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01964807
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 12
    Digitale Medien
    Digitale Medien
    Phosphoramidon enhances allatostatin-mediated inhibition of juvenile hormone biosynthesis in the corpora allta of the cockroach,Diploptera punctata (1992)
    Springer
    Cellular and molecular life sciences 48 (1992), S. 758-761 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Corpora allata ; juvenile hormone biosynthesis ; allatostatins ; phosphoramidon ; enkephalinase ; cockroach ; Diploptera punctata ; ELISA
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract Use of the enkephalinase inhibitor phosphoramidon in the in vitro radiochemical assay for juvenile hormone biosynthesis enhanced allatostatin-mediated inhibition of hormone production by corpora allata of the cockroach,Diploptera punctata. Significant increases in inhibition in day 2 virgin female CA by AST 1 (at 10−7 M) and AST 4 (10−8–10−7 M) were observed in the presence of phosphoramidon (10−5M or greater). No significant increases in inhibition were seen in CA from day 6 mated females with AST 4 (10−9–10−7M) and phosphoramidon combined. Phosphoramidon alone had no effect on JH biosynthesis. Analysis of allatostatin content of the CA, as determined by ELISA, revealed that addition of phosphoramidon to the medium increased the endogenous allatostatin conten in CA of virgin and mated females. The similarity in primary structure between allatostatins and enkephalin-like peptides and their similar distribution makes it probable that phosphoramidon acts by preventing breakdown of allatostatins within the CA.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02124297
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 13
    Digitale Medien
    Digitale Medien
    Petrology and magnetic properties of the Chiang Khan, Thailand, meteorite (1989)
    Springer
    Mineralogy and petrology 40 (1989), S. 173-182 
    Details
    ISSN: 1438-1168
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Geologie und Paläontologie
    Notizen: Summary The Chiang Khan meteorite fell on 18th November, 1981 at Chiang Khan, Thailand. It consists of olivine, orthopyroxene, clinopyroxene, Fe-Ni metal, troilite, chromite, plagioclase, glass, and phosphate in order of abundance. Olivine forms barred or porphyritic chondrules, and its composition is uniform (average Fo80.2), close to the average composition of olivine in equilibrated H chondrites. Orthopyroxene and clinopyroxene also have compositions similar to those in equilibrated H chondrites. Both well-defined chondrules and their broken fragments are present in the recrystallized matrix. Microcrystalline plagioclase and clinopyroxene often occur in the groundmass of chondrules, but clear interstitial plagioclase is absent. Chemical composition of chromite plots in the field of chromites in H chondrites. Chiang Khan meteorite is thus classified as an equilibrated H 5 type chondrite. The equilibrium temperatures estimated by using mineral pairs are as follows: Opx-Cpx 800–900°C; Ol-Chromite 510°C. Water content is 0.24 wt %, and the hydrogen isotopic composition (ΔD) is −89.5‰ In the thermal demagnetization experiment magnetization steadily decreased from 0 to 500°C, whereas the remanent magnetization obtained in the A.C. demagnetization experiment is very unstable, probably owing to the large grain size of the Fe-Ni metal.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01164487
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 14
    Digitale Medien
    Digitale Medien
    Stimulation-dependent changes in synaptic effects on unit activity of medial preoptic nucleus neurones in rats (1980)
    Springer
    Experimental brain research 39 (1980), S. 121-124 
    Details
    ISSN: 1432-1106
    Schlagwort(e): Amygdala ; Medial preoptic nucleus ; Median eminence ; Rat ; Synaptic plasticity
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Stimulation-dependent changes in synaptic effects were observed in medial preoptic nucleus neurones during stimulation of the amygdala or pyriform cortex in anaesthetized female rats. The changes occurred after 35–240 triple pulse stimuli repeated at 0.89 Hz. Median eminence stimulation did not produce any synaptic change. These data show the existence of synaptic plasticity in the neural pathway from the amygdala and pyriform cortex to the medial preoptic nucleus.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00237076
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 15
    Digitale Medien
    Digitale Medien
    Expression of the mutant gene for L-gulono-γ-lactone oxidase in scurvy-prone rats (1989)
    Springer
    Cellular and molecular life sciences 45 (1989), S. 126-129 
    Details
    ISSN: 1420-9071
    Schlagwort(e): L-gulono-γ-lactone oxidase ; ascorbic acid deficiency ; enzyme defect ; rat ; nuclei acid hybridization
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary A mutant strain of Wistar rats with L-gulono-γ-lactone oxidase deficiency has recently been established. To investigate this deficiency by DNA and RNA blot hybridization analyses, a fragment of a previously cloned cDNA encoding rat L-gulono-γ-lactone oxidase was used as a probe. When genomic DNA of the mutant rat was digested with several restriction enzymes, the probe hybridized to fragments of the same sizes as those produced from DNA of normal rats. Poly(A)+RNA from the liver of the mutant rat was found to contain an L-gulono-γ-lactone oxidase-specific mRNA of a normal size at a comparable level to that of normal rats. An in vitro translation experiment revealed that the mRNA programmed the synthesis of an enzyme protein which had the same molecular weight as that of the translational product of the normal mRNA, although the amount synthesized was markedly reduced as compared with that synthesized with the normal mRNA. In accordance with this observation, a very low but definite degree of L-gulono-γ-lactone oxidase activity was detected in the microsomes of the mutant rat by a newly developed, highly sensitive method.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01954844
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 16
    Digitale Medien
    Digitale Medien
    Degeneration of retinal neuroblasts by chinoform-ferric chelate (1982)
    Springer
    Cellular and molecular life sciences 38 (1982), S. 120-122 
    Details
    ISSN: 1420-9071
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The possible mechanism of neuropathic effect of chinoform was investigated using cultured retinal neuroblasts from chick embryos. Retinal neuroblasts completely degenerated by chinoform-ferric chelate within a day. This change, however, was not observed with free chinoform or ferric ion.a-Tocopherol had a potent protective effect on the toxicity of the chelate. From these results, it was concluded that the lipid peroxidation due to ferric ion chelated with chinoform incorporated into the membrane of nerve tissues is the most important step in induction of the neuropathy.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01944564
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 17
    Digitale Medien
    Digitale Medien
    Amygdalar inputs to ADH-secreting supraoptic neurones in rats (1982)
    Springer
    Experimental brain research 48 (1982), S. 420-428 
    Details
    ISSN: 1432-1106
    Schlagwort(e): ADH-neurone ; Amygdala ; Rat ; Supraoptic nucleus
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Effects of amygdala stimulation on the discharge activity of antidromically identified supraoptic neurosecretory neurones were studied in male rats anaesthetized with urethane. Stimulation of the medial and the basal amygdala produced excitation or inhibition of discharge activity both in phasically firing (“phasic”) and in continuously firing (”continuous”) neurones. More “phasic” neurones were excited than were inhibited after medial amygdala stimulation. On the other hand, fewer “continuous” neurones were excited by stimulation of the either amygdala area than were inhibited. This difference of responsiveness between “phasic” and “continuous” neurones is statistically significant. Synaptic inputs to supraoptic neurosecretory neurones after amygdala stimulation were also observed in rats with a lesion of the stria terminalis. Supraoptic nucleus stimulation activated antidromically 14 of the 336 amygdala neurones tested. Since “phasic” neurones have been identified as ADH-secreting neurones, it is concluded that ADH-secreting neurones in the rat supraoptic nucleus receive predominantly excitatory synaptic inputs from the medial amygdala and these amygdalar synaptic inputs are mediated by pathways which are at least in part monosynaptic and are not included in the stria terminalis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00238618
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 18
    Digitale Medien
    Digitale Medien
    Differential effects of naloxone on neuroendocrine responses to fear-related emotional stress (1990)
    Springer
    Experimental brain research 81 (1990), S. 53-58 
    Details
    ISSN: 1432-1106
    Schlagwort(e): Vasopressin ; Oxytocin ; Adrenocorticotrophic hormone ; Emotional stress ; Opioid ; Prolactin ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The effects of an opioid receptor antagonist, naloxone (NAL), were studied on the changes in pituitary hormone secretion induced by emotional stress. Male Wistar rats were trained with tone stimuli paired with electric footshocks and tested with the tone and environmental cue signals for emotional stress of fear acquired by learning as described previously (Onaka et al. 1988). Rats received s.c. injected NAL 30 min before testing at doses of 0, 0.2, 1.0, 5.0 and 25.0 mg/kg b.w. Half the rats were injected with 0.5 M NaCl (20 ml/kg b.w.) together with NAL. In these hypertonic rats plasma vasopressin level was slightly increased after NAL. The increment was statistically significant in control groups but not in experimental groups. However the suppression of vasopressin secretion by emotional stimuli was not changed by NAL. Plasma oxytocin levels were extremely high and not significantly different among experimental, unshocked control and untested control groups. NAL further increased the oxytocin level dose-dependently. NAL did not significantly change plasma adrenocorticotrophic hormone (ACTH) levels and hence did not modify the augmentative response in ACTH secretion to emotional stimuli. Plasma prolactin level was significantly elevated after emotional stimuli and NAL depressed the prolactin level in each of experimental and control groups. After NAL, the magnitude of the facilitatory response in prolactin secretion to emotional stimuli was decreased. Motor activity and its suppressive response to emotional stimuli were not influenced by NAL. In another half of rats under a normal osmotic condition the vasopressin response to emotional stimuli was not affected by NAL. NAL further augmented potentiation of oxytocin secretion after emotional stimuli dose-dependently. Effects of NAL on ACTH level, prolactin level and motor activity were similar to those in rats under hypertonic conditions. These results demonstrate that endogenous opioids are selectively and differentially involved in hypothalamo-hypophysial responses to fear-related emotional stress.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00230100
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 19
    Digitale Medien
    Digitale Medien
    Synergistic activation of rat supraoptic neurosecretory neurons by noxious and hypovolemic stimuli (1986)
    Springer
    Experimental brain research 62 (1986), S. 572-578 
    Details
    ISSN: 1432-1106
    Schlagwort(e): Vasopressin cell ; Noxious input ; Hypovolemia ; Supraoptic nucleus ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The effects of saphenous nerve stimulation on discharge activity of supraoptic neurosecretory (NS) cells were studied in anesthetized rats. Of 112 supraoptic neurosecretory cells, 62 exhibited a ‘phasic’ discharge pattern. The nerve stimulation transiently excited 46 of these 62 ‘phasic’ units, as well as 35 of the 50 remaining ‘non-phasic’ units. No appreciable blood pressure change was noted using PSTHs with 1-ms resolution. Though the nerve stimulation also evoked a flexor reflex of the ipsilateral hind limb, blockage of the hind limb movement with gallamine did not alter the amplitude of the supraoptic cell excitation. The threshold of the nerve stimulation was higher for the excitation than for the flexor reflex. Effects of hypovolemic and hyperosmotic stimuli on discharge activity of ‘phasic’ cells during saphenous nerve stimulation were studied to find a possible interaction between these stimuli. Hemorrhage potentiated the transient excitation evoked by the nerve stimulation in all of the 8 ‘phasic’ cells tested, while no such effect was seen after an injection of hypertonic sodium chloride solution in the 7 ‘phasic’ cells tested. These electrophysiological data suggest that hypovolemic and noxious stimuli potentiate VP secretion in a synergistic manner but that hyperosmotic and noxious stimuli do not.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00236036
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 20
    Digitale Medien
    Digitale Medien
    Vasopressin secretion: suppression after light and tone stimuli previously paired with footshocks in rats (1988)
    Springer
    Experimental brain research 71 (1988), S. 291-297 
    Details
    ISSN: 1432-1106
    Schlagwort(e): ACTH ; Emotional response ; Motor activity ; Vasopressin ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary In an attempt to find whether vasopressin (VP) secretion is suppressed by learned emotional stress, we have given rats under a hypertonic condition simultaneously applied light and tone that had been paired previously with footshocks and have quantified immunoreactive VP (ir-VP) in the plasma. In a training session light (60 watt) and tone (2 kz) of 3-s duration which were paired with electric footshocks (50 Hz, 1-s duration) were given to rats 11 times at an interval of 30 s. Various lengths of time after the training, the rats were tested with light and tone, which were unpaired with footshocks and repeatedly applied every 15 s for 3 min in the box used for training. Hypertonic NaCl (0.5 M, 2 ml/ 100 g b. w.) was injected s. c. 30 min before testing to increase the basal level of plasma VP. After testing, plasma ir-VP was significantly less in the experimental group than in the 0-mA control group of rats that were trained without FS. The values for the experimental group were also significantly less than those of untested control rats that had been trained with FS but were not tested. Plasma osmolality and blood haemoglobin concentration were not significantly different between control and experimental groups. Plasma immunoreactive adrenocorticotrophic hormone (ir-ACTH) level was higher and motor activity as expressed by cumulative time period of body movement during testing was lower in the experimental group than in either of the control groups. The difference in plasma ir-VP between experimental and control groups was statistically significant two days but not seven days after training, whereas ACTH and motor activity in experimental groups were still significantly different from those in control groups seven days after training. The suppressive VP and augmentative ACTH responses to testing disappeared in the rats that had received light and tone repeatedly during the intervening period between training and testing. These data support the hypothesis that emotional stimuli suppress VP secretion.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00247489
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...