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  • 11
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 147 (1988), S. 536-538 
    ISSN: 1432-1076
    Keywords: Pseudohypoparathyroidism ; Hypothyroidism ; Neonatal mass screening ; Bone age
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A girl with type 1a pseudohypoparathyroidism (PHP) presented several hormonal abnormalities. Although she had eluded neonatal thyroid screening, she was diagnosed as having hypothyroidism at the age of 5 months. Thereafter, a diagnosis of PHP was made on the basis of skeletal features of Albright osteodystrophy and lack of both cyclic adenosine monophosphate (c-AMP) and phosphaturic responses after parathyroid hormone (PTH) infusion. The basal levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH) were higher than normal and showed exaggerated responses to luteinizing hormone-releasing hormone (LH-RH). There was no growth hormone (GH) response to arginine infusion, and the prolactin (PRL) response after thyrotropin-releasing hormone (TRH) infusion was also impaired. The stimulating guanine nucleotide-binding protein (Ns) activity of the erythrocytes was reduced to 66.9%. The skeletal age was not delayed at the age of 5 months in spite of the hypothyroid state, and it advanced following thyroxine and vitamin D treatments.
    Type of Medium: Electronic Resource
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  • 12
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 74 (1989), S. 249-255 
    ISSN: 1432-1106
    Keywords: Cholecystokinin-8 ; Glutamic acid de-carboxylase ; Cerebral cortex ; Primate ; Ontogeny
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Concentration of cholecystokinin-8 and the activity of glutamic acid decarboxylase were determined in the various cerebral cortical subdivisions of Japanese monkey (Macaca fuscata fuscata) at three different ages (embryonic 4 months, full-term and adult). The CCK-8 immunoreactive material extracted with 90% methanol from the cerebral cortex of the adult and foetal monkey were shown to be identical with synthetic cholecystokinin-8 by the criterion of co-elution on gel filtration chromatography (Sephadex G-50). The peptide concentration increased dramatically by about 30–80 fold (in terms of protein) and 17–28 fold (in terms of wet weight) between embryonic 4-month-old and full-term monkeys, while the level decreased 1/6–1/16 (protein) and 1/4–1/10 (wet weight) between full-term and adult monkeys. In adults, the highest levels of the peptide was observed in the association cortex, orbital prefrontal cortex and posterior parietal cortex. Glutamic acid decarboxylase activity, on the other hand, gradually increased about 4–10 fold (protein) between embryonic 4-month-old and adult animals and there was little variation in the increase rate among the cerebral subdivisions. In contrast to cholecystokinin-8, no reduction in the enzyme activity occurred between full-term and adult animals. The high level of cholecystokinin-8 in the embryonic period suggests that the peptide may participate in the regulation of the development of primate cerebral cortex.
    Type of Medium: Electronic Resource
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  • 13
    Electronic Resource
    Electronic Resource
    Springer
    Journal of applied electrochemistry 15 (1985), S. 781-783 
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 38 (1985), S. 185-189 
    ISSN: 1432-0649
    Keywords: 42.55 ; 42.60
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A high-power, line-tunable NH3 laser pumped by a TEA CO2 laser has been developed for application to laser isotope separation of tritium. Laser lines from15NH3 are newly observed in a range from 11.24 to 13.23 μm. The performance of an15NH3 laser is compared to that of an14NH3 laser.
    Type of Medium: Electronic Resource
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  • 15
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 5 (1986), S. 543-544 
    ISSN: 1573-4811
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 16
    Electronic Resource
    Electronic Resource
    Springer
    Biochemical genetics 25 (1987), S. 197-203 
    ISSN: 1573-4927
    Keywords: DNA ; polymorphism ; β-globin gene cluster ; Japanese ; AγT-globin gene
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract DNA polymorphism patterns linked to the βA-globin gene were analyzed in healthy Japanese using four different restriction endonucleases. The chromosomes with the βA-globin gene were mapped through an evaluation of the presence of seven different restriction sites (HincII 5′ to ε; HindIII in Gγ and Aγ; HincII in, and 3′ to, ψβ1; AvaII in β; Bam-HI 3′ to β). Among 36 chromosomes analyzed, 20 chromosomes had a haplotype of [+−−−−−+]. Among 55 individuals examined, 7 possessed a homozygous haplotye of [+−−−−−+]. All Japanese with the AγT-globin gene had a subhaplotype of [−++−+] 5′ to the δ-globin gene. Their major haplotypes were [−++−+−+] and [−++−++−]. It was expected that the presence of the AγT-globin gene in Japanese may be deduced from subhaplotypes 5′ to the δ-globin gene.
    Type of Medium: Electronic Resource
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  • 17
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 4 (1966), S. 567-574 
    ISSN: 1741-0444
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Description / Table of Contents: Sommaire Pour simuler l'auto-régulation du volume de fluide du corps humain au moyen de la tonicité, des modèles sont mis au point de différentes manières et l'on prouve que tous permettent de reproduire la réponse type d'organismes quelconques à l'ingestion d'eau. La variété des modèles est dûe à des incertitudes sur la physiologie des reins et des hormones que ces modèles utilisent comme principe de départ.
    Abstract: Zusammenfassung Kontroll-Modelle des Körperflüssigkeitsvolumens durch Tonus sind auf verschiedene Weisen entwickelt worden, und alle zeigen, daß es möglich ist, die charakteristische Antwort des Organismus auf Aufnahme von Wasser zu reproduzieren. Die Verschiedenheit der Modelle ist auf Unsicherheiten der zugrundeliegenden Nieren-und Hormonphysiologie zurückzuführen.
    Notes: Abstract Control models of body fluid volume via tonicity are developed in several ways, and all are demonstrated to be able to reproduce the characteristic response of organisms to ingestion of water. The diversity of models is due to uncertainties in renal and hormonal physiology, on which they are based.
    Type of Medium: Electronic Resource
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  • 18
    Electronic Resource
    Electronic Resource
    Springer
    Experimental mechanics 25 (1985), S. 154-160 
    ISSN: 1741-2765
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Some fundamental problems on the optical method of caustics, which is used to determine the value of the stress-intensity factor, are studied. The paper shows that the radiusr o of the initial curve considerably affects the results and describes a method to eliminate this effect. This method is also applied to the biaxial-stress fracture problem. It is shown that the biaxial stress affects the fracture toughness of thin specimens of Plexiglas sheets and that the fatigue-crack-growth rate is increased due to the compressive stress along the crack line.
    Type of Medium: Electronic Resource
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  • 19
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 29 (1987), S. 236-241 
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Commercial cellulase preparations from Trichoderma viride and Aspergillus niger were immobilized on porous silica glass and ceramics such as alumina and titania with titanium tetrachloride (TiCl4) and on their silanized derivatives with glutaraldehyde (GLUT). The amounts of the immobilized enzymes were in the range 10-50 mg/g carrier (dry) depending on the kind of carrier and immobilization method. Their activities toward carboxymethyl cellulose (CMC), xylan, aryl-β-glucoside, and aryl-β-xyloside were 3-53% of those of the native enzymes. The optimum pH of the enzymes shifted to the acidic side in most cases, whereas the optimum temperatures were nearly the same as those of native ones. The activity of immobilized enzyme preparations towards CMC did not change significantly during continuous operation over a periods of 60 days. Finally, xylan was hydrolyzed with the immobilized enzymes, and the sugars formed were investigated.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 20
    Electronic Resource
    Electronic Resource
    Springer
    Hyperfine interactions 21 (1985), S. 79-83 
    ISSN: 1572-9540
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Expectation values of the total spinS of nucleons in nuclei are very quenched. This quenching is shown to be hardly explained by the mixture ofΔ-hole states. The quenching thus provides the best evidence for the role of non-central parts of the nucleon-nucleon interaction, especially the tensor interaction.
    Type of Medium: Electronic Resource
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