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  • 11
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 57 (1988), S. 159-162 
    ISSN: 1439-6327
    Keywords: Atrial natriuretic peptide ; Heart rate ; Muscular exercise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Circulating atrial natriuretic peptide (ANP) level was determined during physical exercise to investigate the correlation between changes in ANP level and heart rate increases. Six subjects exercised at a work level of 75% $$\dot V_{{\text{O}}_{{\text{2 max}}} }$$ for 30 min, two also performed two successive exercises at 75% $$\dot V_{{\text{O}}_{{\text{2 max}}} }$$ while two more exercised for longer at 55% $$\dot V_{{\text{O}}_{{\text{2 max}}} }$$ · Plasma ANP levels and heart rate increased in all the exercising subjects. At the end of the exercise, the ANP level fell immediately, suggesting an immediate reduction in ANP secretion by the heart. Pre-exercise values were reached after 30 min. Successive exercises gave the same heart rate related ANP patterns without previous secretory episodes having any effect. These results lead to the conclusion that ANP intervenes in the cardiovascular adjustments to exercise.
    Type of Medium: Electronic Resource
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  • 12
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 55 (1986), S. 123-129 
    ISSN: 1439-6327
    Keywords: Plasma volume ; Aldosterone ; Renin activity ; Arginine vasopressin ; Cortisol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This study examines the relationships between vascular changes and endocrine responses to prolonged exercise in the heat, associated with dehydration and rehydration by fluids of different osmolarity. Five subjects were exposed, in a 34
    Type of Medium: Electronic Resource
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  • 13
    ISSN: 1439-6327
    Keywords: Hydration ; Growth hormone ; Prolactin ; Exercise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of progressive rehydration with either water or a carbohydrate solution on the plasma growth hormone (GH) and prolactin (PRL) response to exercise was examined together with plasma somatostatin. Five subjects underwent four 3-h experimental sessions at 36°C in which 25-min exercise periods alternated with 5-min rest periods. The sessions were conducted without fluid replacement (DH) or under rehydration with either water or isosmotic carbohydrate solutions AISO (acid) or NISO (neutral). The fluid was given every 10 min after the 1st h of exercise. Plasma GH increased significantly (p 〈 0.01) under DH after 2 and 3 h of exercise; this increase was prevented by rehydration with water, AISO and NISO. Plasma glucose was significantly higher following AISO and NISO rehydration compared with DH. This possibly influenced the GH response, but there was no difference between plasma glucose levels under DH and water rehydration at any time. The solutions tended to attenuate the increase in heart rate, rectal temperature and plasma cortisol, suggesting that the lack of GH response under rehydration conditions is a result of decreasing physiological stress levels. The GH response could not be explained by plasma somatostatin, which tended to decline in all sessions. Plasma PRL did not increase in any of the sessions, confirming that exercise without rehydration is a more potent stimulator of GH than of PRL. It is concluded that progressive rehydration with water is sufficient to prevent the exercise-induced increase in plasma GH.
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 43 (1980), S. 253-261 
    ISSN: 1439-6327
    Keywords: Noise ; Plasma catecholamines ; Pituitary adrenal hormones ; Man
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To evaluate the immediate effect of exposure to a high level of noise on the sympatho-adrenal and pituitary-adrenal systems, measurements were made of circulating catecholamines, growth hormone, ACTH, and cortisol in seven normal male subjects. They were studied on two random experimental days: a control day and a noise-exposure day with an intermittent noise alternating between 99 dB (A) and 45 dB (A) for 2 h. Analysis did not reveal any variation in the plasma levels of norepinephrine (NE), epinephrine (E) or dopamine (D), measured every 20 min, which might have been related to noise exposure. Similarly, analysis of the 2-h urine samples collected from 8 a.m. to 2 p.m. revealed no significant changes in urinary catecholamine excretion. Plasma levels of GH and ACTH did not differ significantly from those for control days, but cortisol showed a brief, significant levelling-off in its pattern during the exposure period. The data demonstrate that exposure to a high level of noise, although considered as “unpleasant”, does not induce any important endocrinological changes in man. These conclusions differ from those for studies on animals where reactions to noise may be related to a more general stressing situation.
    Type of Medium: Electronic Resource
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  • 15
    ISSN: 1439-6327
    Keywords: Exercise ; Temperature regulation ; Sweat rate ; Cardiovascular responses
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Five healthy young men exercised on an ergocycle for six 25-min periods separated by 5-min rest intervals in a warm dry environment (36°C). After 1 h of exercise without fluid intake, the subjects continued to be dehydrated or were rehydrated either with water (W) or with isosmotic electrolyte carbohydrate solutions, either acidic (AISO) or close to neutrality (NISO). The average amount of the fluid ingested progressively every 10 min (120 ml) at 20°C was calculated so as to compensate for 80% of the whole body water loss due to exercise in the heat. Dehydration associated with hyperosmotic hypovolaemia elicited large increases in heart rate (HR), and in rectal temperature (T re), while no decrease was found in either whole body or local sweat rates. Rehydration with water significantly reduced the observed disturbances, except for plasma osmolality and Na+ concentration which were significantly lower than normal. With both AISO and NISO there was no plasma volume reduction and osmolality increase. Although a plasma volume expansion was induced by NISO ingestion, the cardiac cost was not improved, as reflected by the absence of a decrease in HR. With NISO, sweating was not enhanced andT re tended to remain higher. It is concluded that efficient rehydration requires the avoidance of plasma volume expansion at the expense of interstitial and intracellular rehydration. During rehydration by oral ingestion of fluid, the pH of the drink may be an important factor; its effect remains unclear, however.
    Type of Medium: Electronic Resource
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  • 16
    ISSN: 1439-6327
    Keywords: Atrial ejection force ; Atrial natriuretic factor ; Echographic parameters ; Heart transplantation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The increase in plasma concentration of atrial natriuretic factor in heart transplant patients has not been fully elucidated. Besides an eventual pressure or volume overload leading to passive atrial distension, the atrial tension developed during atrial systole, or atrial ejection force, which may be increased by the transplantation procedure, is an important determinant of atrial natriuretic factor release. We therefore determined the plasma concentration of atrial natriuretic factor and the maximal atrial ejection force in 15 heart transplant patients and 8 controls, matched for age and body mass. Atrial ejection force, as defined as the force exerted by the left atrium to accelerate blood into the left ventricle during atrial systole, was obtained using combined two-dimensional imaging and doppler echocardiography. Serum creatinin concentrations, heart rate [91.9 (SD 13.2) vs 71.8 (SD 10.9) beats · min−1], mean arterial blood pressure [103.9 (SD 9.8) vs 87.4 (SD 5.8) mmHg, 13.85 (SD 1.31) vs 11.65 (SD 0.77) kPa], left ventricular posterior wall thickness and interventricular septum thickness were higher in heart transplant patients compared to controls. Plasma concentration of atrial natriuretic factor was also elevated in heart transplant patients [63.9 (SD 18.1) vs 34.0 (SD 3.2) pg · ml−1; P〈0.001]. In contrast, although the left atrial area was greater in heart transplant patients [28.2 (SD 4.8) vs 15.8 (SD 2.5) cm2; P〈0.001], mitral area, transmitral Doppler A-wave maximal velocity and atrial ejection force were similar in transplant and in control patients [7.7 (SD 3.5) vs 8.9 (SD 2.8) kdyn, 77 (SD 35) vs 89 (SD 28) mN]. No significant correlation was observed between concentration of atrial natriuretic factor and atrial ejection force, either in heart transplant patients or in controls. Thus, the elevated plasma concentration of atrial natriuretic factor observed in these heart transplant patients was multifactorial in origin, and was considered to depend upon an hypersecretion rather than upon a decreased clearance rate. Moreover, it is suggested that the atrial ejection force was unlikely to have participated in this enhanced release of atrial natriuretic factor.
    Type of Medium: Electronic Resource
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