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  • 11
    Electronic Resource
    Electronic Resource
    Springer
    Journal of computational neuroscience 9 (2000), S. 133-148 
    ISSN: 1573-6873
    Keywords: membrane noise ; active ion channels ; Markov kinetic models ; stochastic ion channels
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Medicine , Physics
    Notes: Abstract Voltage-gated ion channels in neuronal membranes fluctuate randomly between different conformational states due to thermal agitation. Fluctuations between conducting and nonconducting states give rise to noisy membrane currents and subthreshold voltage fluctuations and may contribute to variability in spike timing. Here we study subthreshold voltage fluctuations due to active voltage-gated Na+ and K+ channels as predicted by two commonly used kinetic schemes: the Mainen et al. (1995) (MJHS) kinetic scheme, which has been used to model dendritic channels in cortical neurons, and the classical Hodgkin-Huxley (1952) (HH) kinetic scheme for the squid giant axon. We compute the magnitudes, amplitude distributions, and power spectral densities of the voltage noise in isopotential membrane patches predicted by these kinetic schemes. For both schemes, noise magnitudes increase rapidly with depolarization from rest. Noise is larger for smaller patch areas but is smaller for increased model temperatures. We contrast the results from Monte Carlo simulations of the stochastic nonlinear kinetic schemes with analytical, closed-form expressions derived using passive and quasi-active linear approximations to the kinetic schemes. For all subthreshold voltage ranges, the quasi-active linearized approximation is accurate within 8% and may thus be used in large-scale simulations of realistic neuronal geometries.
    Type of Medium: Electronic Resource
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  • 12
    Electronic Resource
    Electronic Resource
    Springer
    Autonomous robots 7 (1999), S. 211-224 
    ISSN: 1573-7527
    Keywords: optomotor system ; analog VLSI ; optic flow ; motion detector ; insect vision
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Sensing visual motion gives a creature valuable information about its interactions with the environment. Flies in particular use visual motion information to navigate through turbulent air, avoid obstacles, and land safely. Mobile robots are ideal candidates for using this sensory modality to enhance their performance, but so far have been limited by the computational expense of processing video. Also, the complex structure of natural visual scenes poses an algorithmic challenge for extracting useful information in a robust manner. We address both issues by creating a small, low-power visual sensor with integrated analog parallel processing to extract motion in real-time. Because our architecture is based on biological motion detectors, we gain the advantages of this highly evolved system: A design that robustly and continuously extracts relevant information from its visual environment. We show that this sensor is suitable for use in the real world, and demonstrate its ability to compensate for an imperfect motor system in the control of an autonomous robot. The sensor attenuates open-loop rotation by a factor of 31 with less than 1 mW power dissipation.
    Type of Medium: Electronic Resource
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  • 13
    Electronic Resource
    Electronic Resource
    Springer
    Biological cybernetics 50 (1984), S. 15-33 
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract This investigation aims at exploring some of the functional consequences of single neurons containing active, voltage dependent channels for information processing. Assuming that the voltage change in the dendritic tree of these neurons does not exceed a few millivolts, it is possible to linearize the non-linear channel conductance. The membrane can then be described in terms of resistances, capacitances and inductances, as for instance in the small-signal analysis of the squid giant axon. Depending on the channel kinetics and the associated ionic battery the linearization yields two basic types of membrane: a membrane modeled by a collection of resistances and capacitances and membranes containing in addition to these components inductances. Under certain specified conditions the latter type of membrane gives rise to a membrane impedance that displays a prominent maximum at some nonzero resonant frequency f max. We call this type of membrane quasi-active, setting it apart from the usual passive membrane. We study the linearized behaviour of active channels giving rise to quasi-active membranes in extended neuronal structures and consider several instances where such membranes may subserve neuronal function: 1. The resonant frequency of a quasi-active membrane increases with increasing density of active channels. This might be one of the biophysical mechanisms generating the large range over which hair cells in the vertebrate cochlea display frequency tuning. 2. The voltage recorded from a cable with a quasi-active membrane can be proportional to the temporal derivative of the injected current. 3. We modeled a highly branched dendritic tree (δ-ganglion cell of the cat retina) using a quasi-active membrane. The voltage attenuation from a given synaptic site to the soma decreases with increasing frequency up to the resonant frequency, in sharp contrast to the behaviour of passive membranes. This might be the underlying biophysical mechanism of receptive fields whose dimensions are large for rapid signals but contract to a smaller area for slow signals as suggested by Detwiler et al. (1978).
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 317 (1985), S. 314-319 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Descriptions of physical properties of visible surfaces, such as their distance and the presence of edges, must be recovered from the primary image data. Computational vision aims to understand how such descriptions can be obtained from inherently ambiguous and noisy data. A recent development in ...
    Type of Medium: Electronic Resource
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  • 15
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 377 (1995), S. 294-295 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] CRICK AND KOCH REPLY — An unstated assumption in our thinking1 is that, in terms of neural 'computation', we make a distinction between the computations themselves and their results. A rough analogy would be between all the activity within a computer (the computations) and the results of ...
    Type of Medium: Electronic Resource
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  • 16
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 375 (1995), S. 121-123 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] It is usually assumed that people are visually aware of at least some of the neuronal activity in the primary visual area, V1, of the neocortex. But the neuroanatomy of the macaque monkey suggests that, although primates may be aware of neural activity in other visual cortical ...
    Type of Medium: Electronic Resource
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  • 17
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 381 (1996), S. 123-124 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE most famous twentieth-century philosophical treatise ends with the enigmatic invocation "Wovon man nicht sprechen kann, daruber mufl man schweigen" ("Whereof one cannot speak, thereof one must be silent"). David Chalmers has obviously considered these words as a challenge and has written a ...
    Type of Medium: Electronic Resource
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  • 18
    Electronic Resource
    Electronic Resource
    Springer
    International journal of computer vision 6 (1991), S. 133-145 
    ISSN: 1573-1405
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract Single-scale approaches to the determination of the optical flow field from the time-varying brightness pattern assume that spatio-temporal discretization is adequate for representing the patterns and motions in a scene. However, the choice of an appropriate spatial resolution is subject to conflicting, scene-dependent, constraints. In intensity-base methods for recovering optical flow, derivative estimation is more accurate for long wavelengths and slow velocities (with respect to the spatial and temporal discretization steps). On the contrary, short wavelengths and fast motions are required in order to reduce the errors caused by noise in the image acquisition and quantization process. Estimating motion across different spatial scales should ameliorate this problem. However, homogeneous multiscale approaches, such as the standard multigrid algorithm, do not improve this situation, because an optimal velocity estimate at a given spatial scale is likely to be corrupted at a finer scale. We propose an adaptive multiscale method, where the discretization scale is chosen locally according to an estimate of the relative error in the velocity estimation, based on image properties. Results for synthetic and video-acquired images show that our coarse-to-fine method, fully parallel at each scale, provides substantially better estimates of optical flow than do conventional algorithms, while adding little computational cost.
    Type of Medium: Electronic Resource
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  • 19
    Electronic Resource
    Electronic Resource
    Springer
    International journal of computer vision 12 (1994), S. 17-42 
    ISSN: 1573-1405
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract Standard techniques for segmenting color images are based on finding normalized RGB discontinuities, color histogramming, or clustering techniques in RGB or CIE color spaces. The use of the psychophysical variable hue in HSI space has not been popular due to its numerical instability at low saturations. In this article, we propose the use of a simplified hue description suitable for implementation in analog VLSI. We demonstrate that if theintegrated white condition holds, hue is invariant to certain types of highlights, shading, and shadows. This is due to theadditive/shift invariance property, a property that other color variables lack. The more restrictive uniformly varying lighting model associated with themultiplicative/scale invariance property shared by both hue and normalized RGB allows invariance to transparencies, and to simple models of shading and shadows. Using binary hue discontinuities in conjunction with first-order type of surface interpolation, we demonstrate these invariant properties and compare them against the performance of RGB, normalized RGB, and CIE color spaces. We argue that working in HSI space offers an effective method for segmenting scenes in the presence of confounding cues due to shading, transparency, highlights, and shadows. Based on this work, we designed and fabricated for the first time an analog CMOS VLSI circuit with on-board phototransistor input that computes normalized color and hue.
    Type of Medium: Electronic Resource
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  • 20
    Electronic Resource
    Electronic Resource
    Springer
    International journal of computer vision 4 (1990), S. 211-223 
    ISSN: 1573-1405
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract The detection of discontinuities in motion, intensity, color, and depth is a well-studied but difficult problem in computer vision [6]. We discuss the first hardware circuit that explicitly implements either analog or binary line processes in a deterministic fashion. Specifically, we show that the processes of smoothing (using a first-order or membrane type of stabilizer) and of segmentation can be implemented by a single, two-terminal nonlinear voltage-controlled resistor, the “resistive fuse”; and we derive its current-voltage relationship from a number of deterministic approximations to the underlying stochastic Markov random fields algorthms. The concept that the quadratic variation functionals of early vision can be solved via linear resistive networks minimizing power dissipation [37] can be extended to non-convex variational functionals with analog or binary line processes being solved by nonlinear resistive networks minimizing the electrical co-content. We have successfully designed, tested, and demonstrated an analog CMOS VLSI circuit that contains a 1D resistive network of fuses implementing piecewise smooth surface interpolation. We furthermore demonstrate the segmenting abilities of these analog and deterministic “line processes” by numerically simulating the nonlinear resistive network computing optical flow in the presence of motion discontinuities. Finally, we discuss various circuit implementations of the optical flow computation using these circuits.
    Type of Medium: Electronic Resource
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