Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 11
    Electronic Resource
    Electronic Resource
    What is the role of serology in assessing Helicobacter pylori eradication? (2003)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 18 (2003), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aim : To assess the decline in Helicobacter pylori antibodies after eradication of infection.Methods : The H. pylori status was determined at entry (D0) by culture and histology performed on antral biopsies and after eradication treatment at day 42 (day 42) and after 6 months (M6) by the 13C-urea breath test. The EIA kits used to determine the anti-H. pylori antibody titre were HM-CAP (immunoglobulin-G) and PP-CAP (immunoglobulin-A) kits (Enteric Products, Inc.) and Pyloriset EIA-G (Orion Diagnostica).Results : Ninety-three patients were included. For 82 patients who were successfully treated, no kit was sufficiently accurate at D42 to show eradication. The antibody titre decreased for HM-CAP, PP-CAP and Pyloriset EIA-G by a mean of 35.6%, 41.2% and 64.7% between D0 and M6, respectively. According to the cut-off values defined by the manufacturers, 8.5% (PP-CAP, Pyloriset EIA-G) and 9.7% (HM-CAP) of the patients became H. pylori negative at M6. Using a 25% decrease in antibody titre between D0 and M6 as a threshold for H. pylori eradication, specificity was 100% for HM-CAP, 89.9% for Pyloriset EIA-G and 100% for PP-CAP, whereas the sensitivity was 76.8%, 98.8% and 72%, respectively.Conclusion : An antibody titre decrease of 25% at M6 was found to be accurate in confirming H. pylori eradication.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2003.01716.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 12
    Electronic Resource
    Electronic Resource
    Review article: the treatment of refractory Helicobacter pylori infection (2003)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 17 (2003), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The occurrence of refractory Helicobacter pylori infection is increasing. When the bacteria are not eradicated it means that the antibiotics have not reached the gastric mucosa at a sufficient concentration and over a sufficient time lapse to kill them. The main reasons for this are poor patient compliance, resistant bacteria, low gastric pH and a high bacterial load. Therefore, when administering a new treatment, it is important to choose antibiotics which do not face resistance problems and which increase the dosage of antisecretory drugs and the duration of treatment and, if possible, to add a topical agent such as bismuth salt.The recommended empirical strategy is to prescribe quadruple therapy or, alternatively, 2-week triple therapy including amoxicillin–metronidazole, tetracycline–metronidazole or amoxicillin–rifabutin. However, when H. pylori is susceptible, clarithromycin can still be used. In the case of a high level of metronidazole resistance, furazolidone can be employed. In each case, it is important to ensure good patient compliance, and counselling is helpful in this regard. However, the best approach remains the prevention of refractory H. pylori infection and, for this purpose, antimicrobial susceptibility testing before first-line therapy is important and should be encouraged.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2003.01592.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 13
    Electronic Resource
    Electronic Resource
    Short-course therapy with amoxycillin–clarithromycin triple therapy for 10 days (ACT-10) eradicates Helicobacter pylori and heals duodenal ulcer (1997)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 11 (1997), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Whilst the role of Helicobacter pylori eradication in managing duodenal ulcers has been established, consensus regarding the ideal regimen has not been achieved.〈section xml:id="abs1-2"〉〈title type="main"〉Methods:Patients with H. pylori-positive active duodenal ulcer were randomly assigned to receive triple therapy with amoxycillin 1000 mg b.d. + clarithromycin 500 mg b.d. + omeprazole 20 mg daily for 10 days (ACT-10) or dual therapy with clarithromycin 500 mg t.d.s. + omeprazole 40 mg daily for 14 days (Dual). No additional acid suppression was provided following eradication therapy. Endoscopy, with biopsy for culture and histology, as well as 13C-urea breath testing (13C-UBT) were performed pre-treatment to assess H. pylori infection. H. pylori eradication was established at 4–6 weeks follow-up with culture (2 antral, 1 corpus biopsies), histology (2 antral biopsies), and 13C-UBT. Ulcer healing by endoscopy and change in clinical symptoms were also assessed at 4–6 weeks.〈section xml:id="abs1-3"〉〈title type="main"〉Results:Two hundred and sixty-seven (267) patients were randomized to ACT-10 (n=137) or Dual therapy (n=130). By per-protocol and intention-to-treat analyses, H. pylori eradication at 4–6 weeks follow-up was 91% (115/127) and 88% (120/136), respectively, for ACT-10 patients and 59% (68/115) and 55% (72/130), respectively, for Dual therapy patients (P〈0.001 for both analyses). Ulcer healing was high in both treatment groups: ACT-10, 93% (118/127) and 90% (122/136), respectively; and Dual therapy, 91% (104/114) and 85% (111/130), respectively. Pre-treatment resistance to clarithromycin was low (4%, 8/214) as compared to metronidazole resistance which was over 40%. Emergence of resistance to clarithromycin was observed in 2% of patients receiving ACT-10 and in 25% of those receiving Dual therapy. ACT-10 and Dual therapy patients experienced similar rates of drug-related adverse events (33% vs. 32%, respectively) and discontinuation from therapy due to an adverse event (1.5% vs. 5%, respectively). More than 90% of patients were compliant with each prescribed medication.〈section xml:id="abs1-4"〉〈title type="main"〉Conclusion:In patients with active duodenal ulcer, a 10-day course of amoxycillin–clarithromycin-based triple therapy without additional acid suppression is highly effective in eradicating H. pylori and healing duodenal ulcer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.1997.00223.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 14
    Electronic Resource
    Electronic Resource
    In vitro isolation of a transovarially transmitted bacterium from the leafhopper Euscelidius variegatus (Hemiptera: Cicadellidae)
    Amsterdam : Elsevier
    Journal of Invertebrate Pathology 48 (1986), S. 66-73 
    Details
    ISSN: 0022-2011
    Keywords: Colladonus ; Euscelidius variegatus ; Euscelus ; Fieberiella ; Macrosteles ; Scaphytopius ; endosymbiont ; symbiote ; transovarial
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0022-2011(86)90144-8
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 15
    Electronic Resource
    Electronic Resource
    Acute otitis media in children: A study of nasopharyngeal carriage of potential pathogens and therapeutic efficacy of cefixime and amoxicillin-clavulanate (1995)
    Springer
    Infection 23 (1995), S. S79 
    Details
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Wir führten eine große, offene, randomisierte Multizenterstudie in ganz Frankreich durch, in der die Wirksamkeit und Sicherheit der Cefixim-Suspension (8 mg/kg/Tag, zweimal täglich 10 Tage) mit derjenigen der Amoxicillin-Clavulansäure-Suspension (80 mg/kg/Tag dreimal täglich 10 Tage) bei 510 Kindern (Alter 6–36 Monate) mit akuter Otitis media verglichen wurde. Am häufigsten war der Nasopharynx zu Therapiebeginn durchStreptococcus pneumoniae (51,5%),Haemophilus influenzae (45%) undMoraxella catarrhalis (30,2%) besiedelt. 32,1% derH. influenzae und 95,3% derM. catarrhalis-Isolate waren β-Lactamasebildner. Bei 39,7% der Isolate vonS. pneumoniae fand sich einge-schränkte Penicillinempfindlichkeit. In der mit Cefixim behandelten Gruppe lag die klinische Erfolgsrate bei 87,8% (223/254), in der mit Amoxicillin-Clavulansäure behandelten Gruppe bei 87,0% (215/247). Die Verlaufskontrolle nach 5 Wochen deckte bei 15,7% (31/197) der mit Cefixim und bei 15,6% (32/205) der mit Amoxicillin-Clavulansäure behandelten Patienten Rezidive auf. Wir schließen, daß die beiden Behandlungsschemata in der Therapie der akuten Otitis media bei Kindern gleich wirksam sind.
    Notes: Summary We conducted a large, multicenter, randomized, open-label study throughout France comparing the efficacy and safety of cefixime suspension (8 mg/kg/day, b. i. d., for 10 days) versus amoxicillin-clavulanate suspension (80 mg/kg/day, t. i. d., for 10 days) in 510 children (ages 6 to 36 months) with acute otitis media. The most frequent microorganisms colonizing the nasopharynx at the start of treatment wereStreptococcus pneumoniae (51.5%),Haemophilus inflenzae (45%) andMoraxella catarrhalis (30.2%). Rates of β-lactamase positivity were 32.1% and 95.3% forH. influenzae andM. catarrhalis, respectively. Decreased susceptibility ofS. pneumoniae to penicillin was found in 39.7% of isolates. Clinical efficacy was 87.8% (223/254) for cefixime and 87.0% (215/247) for amoxicillin-clavulanate. At the 5-week follow-up visit, relapse had occurred in 15.7% (31/197) of cefixime-treated patients and in 15.6% (32/205) of those treated with amoxicillin-clavulanate. We conclude that these two regimens are equally effective in acute otitis media in children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01742989
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 16
    Electronic Resource
    Electronic Resource
    Serogroups and biotypes of human strains ofCampylobacter jejuni andCampylobacter coli isolated in France (1987)
    Springer
    European journal of clinical microbiology & infectious diseases 6 (1987), S. 641-645 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The Lior schemes were used for biotyping and serogrouping campylobacter strains isolated during a three year period in Bordeaux, France. Of the 226 strains tested, 176 were Campylobacter jejuni and 50 Campylobacter coli. Campylobacter jejuni biotype I was the most prevalent (48.2 %). Biotypes III and IV of Campylobacter jejuni were rare (3.9% and 1.3% respectively). Serogroup 4 (17.7%) was the most common serogroup followed by serogroups 46 (11.0%), 29 (10.1%), 9 and 36 (7.9%). Eight serogroups constituted 73 % of the strains. The distribution was similar from year to year and an association between a particular biotype and serogroup was not observed. During the study period four family outbreaks and seven recurrences of infection were observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02013060
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 17
    Electronic Resource
    Electronic Resource
    Incidence and virulence ofAeromonas species in feces of children with diarrhea (1986)
    Springer
    European journal of clinical microbiology & infectious diseases 5 (1986), S. 311-316 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aeromonas spp. occurring in feces of children with diarrhea were studied. Forty-eight strains were isolated from 2,025 specimens during a one year period. Only 11 of 44 strains tested yielded virulence factors (cytotoxin, hemolysin and hemagglutinin). Six strains were identified as Aeromonas sobria and five as Aeromonas hydrophila.The other strains isolated were identified as Aeromonas caviae.The biochemical characteristics associated with virulence factors were a positive Voges-Proskauer reaction, production of gas from glucose, fermentation of mannose, and absence of β-lactosidase. Beta-D-glucosidase and esculin hydrolysis were the main characteristics used to differentiate Aeromonas sobria from the other two species. The incidence of Aeromonas spp. with virulence factors in feces of children with diarrhea would seem to vary widely from one area to another.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02017787
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 18
    Electronic Resource
    Electronic Resource
    Haemophilus species in the human gastrointestinal tract (1988)
    Springer
    European journal of clinical microbiology & infectious diseases 7 (1988), S. 437-438 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01962361
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 19
    Electronic Resource
    Electronic Resource
    Isolation ofCampylobacter species by filtration (1985)
    Springer
    European journal of clinical microbiology & infectious diseases 4 (1985), S. 437-438 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02148709
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 20
    Electronic Resource
    Electronic Resource
    In vitro activity of rifaximin againstHelicobacter pylori (1994)
    Springer
    European journal of clinical microbiology & infectious diseases 13 (1994), S. 184-186 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01982198
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...