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  • 11
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Inorganic Biochemistry 51 (1993), S. 46 
    ISSN: 0162-0134
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 12
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Biochemical and Biophysical Methods 27 (1993), S. 95-103 
    ISSN: 0165-022X
    Keywords: Affinity chromatography ; Immunoabsorption ; Retinoid X receptor ; Thyroid hormone ; Thyroid hormone nuclear recptor ; Thyroid hormone response element
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 13
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 23 (1988), S. 4406-4414 
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Foam materials based on metal and several polymers were transformed so that their cellular architecture became re-entrant, i.e. with inwardly protruding cell ribs. Foams with re-entrant structures exhibited negative Poisson's ratios as well as greater resilience than conventional foams. Foams with negative Poisson's ratios were prepared using different techniques and materials and their mechanical behaviour and structure evaluated.
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Annals of biomedical engineering 6 (1978), S. 167-171 
    ISSN: 1573-9686
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract To elucidate the contribution of smooth muscle to the mechanical properties of artery and to study its interaction with other tissue components, an enzymolysis technique has been used. Fresh canine artery was cut into circumferential strips, and a stressrelaxation test was performed in a Krebs-Ringer solution while continuously bubbling an O2−CO2 gas mixture. An aortic smooth muscle stimulant, norepinephrine, was perfused during the stress-relaxation test, before and after removing collagen with collagenase. The collagen-free artery did not show any contraction due to the smooth muscle, in contrast to the intact artery. This indicates that there may be important interactions between the collagen matrix and smooth muscle. This new technique can be used to study the contribution of smooth muscle to the mechanical properties of aorta.
    Type of Medium: Electronic Resource
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  • 15
    Electronic Resource
    Electronic Resource
    Springer
    Annals of biomedical engineering 8 (1980), S. 93-101 
    ISSN: 1573-9686
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract The effect of small direct current (∼8μA) upon the tensile strength of the interfacial union between porous metal and polymer implants (100–200 μm diam pores) and bone was studied in the femur of dogs. The present results show that the electrical stimulation accelerates the rate of bony tissue growth into pores of the implants regardless of the nature of the materials tested. It is particularly exciting to find that the porous metal can be used as an electrode as well as an implant. This implies that an ordinary prosthesis made of metal can be made porous and the fixation time period can be shortened by the electrical stimulation. This has an enormous potential for all the direct fixation prostheses for rapid achievement of fixation.
    Type of Medium: Electronic Resource
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  • 16
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 35 (1995), S. 741-753 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: For a science-based design of the Powder Injection Molding (PIM) process, it would be desirable for designers to have a numerical analysis tool capable of predicting the PIM filling process as a design aid. In this regard, the present study is aimed at developing a numerical analysis system to simulate the PIM filling process based on a new physical modeling taking into account rheological characteristics of powder/binder mixtures, namely the yield stress and the apparent slip phenomena. In particular, two different slip models were employed to represent the apparent slip phenomena. In accordance with the new physical modeling, the numerical simulation of the PIM filling process was accomplished by combining a finite element method and a finite difference method. It was found that the slip layer plays a role of not only a lubricating layer but also a thermal insulation layer. In this aspect, the slip layer model seems to represent the apparent slip phenemena better than the slip velocity model with regard to both the momentum and the thermal transport phenomena. The present paper presents the physical modeling, numerical scheme, and some numerical analysis results showing the effect of the yield stress and slip phenomena.
    Additional Material: 18 Ill.
    Type of Medium: Electronic Resource
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  • 17
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: In this paper we have reviewed the feasibility of using a shock wave lithotripter to loosen the interface between the bone and acrylic bone cement for revision arthroplasty. We have reviewed the physics of shock wave and its applications in medicine, especially its interaction with tissues. The calculations show that the energy is greatly reduced at the interface both in the soft tissue-bone interface and cement-bone interface. On the other hand, a tensile and compressive pressure can be operated at the cement-bone interface that can cause the interface to break if the pressure exceeds the tensile strength of the cement-bone interface.Subsequent papers will deal with in vitro and in vivo application of the shock wave in the treatment of the cement-bone interface in order to weaken it and consequently for easier extraction of bone cement from the intramedullary canal.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 18
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 4 (1993), S. 55-60 
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Ferromagnetic Ni—Cu alloy wires were characterized in order to obtain well-defined thermoseeds for application in interstitial hyperthermia of prostate cancer. Thermoseeds have been produced which possess Curie points in the therapeutic hyperthermia range, approximately 40 to 50 °C. The effect of thermal treatment and composition on the heating characteristics of the thermoseeds were investigated. The preliminary study shows that the recrystallization is crucial for altering thermoseeds' heating characteristics. Obtaining thermoseeds which behave as desired depends on changes in annealing times and temperatures. One may increase the maximum heating temperature (similar to Curie temperature) by increasing the annealing time and cooling time. Decreasing the lower annealing plateau temperature also increases the maximum seed heating temperature. Higher nickel content compositions did not affect rise time but increased the maximum heating temperature. © 1993 John Wiley & Sons, Inc.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 19
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991), S. 161-170 
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: In order to apply the extracorporeal shock wave lithotripter (ECWSL) technique to the loosening of the bone-cement interface for the extraction of the cement during revision arthroplasty it is essential to know the dose-response characteristics. The present study shows that the number of shocks needed to break the interface between a 2- and 6-mm-thick bovine femoral bone and bone cement is similar to the fatigue behavior of a material, that is, Log(N) = C(kV) + D, where N is the number of shock impulses, kV is the power setting of the lithotripter machine in kilovolts, and C and D are constants. Iso-pressure distribution of the traveling shock wave front through a simulated bone in a Plexiglass® tube using Fuji® pressure film showed quantitative pressure contours from which one can understand the effective area of shock wave and its distribution. The most effective area of the shock wave was about 1.5 cm in diameter at 23 and 25 kV with pressure at least 7.0 MPa which is more than sufficient to break the bone-cement interface in tension.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
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  • 20
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The present study was conducted to compare the push-out strength of the treated and control samples obtained after implantation of intramedullary rod in canine femurs with bone cement to simulate the femoral stem implantation for 2 weeks, 3 and 6 months. Contralateral femur served as control. The result showed a significant decrease in push-out interfacial strength after shock wave treatment (average 48.4% decrease compared with control, p 〈 0.0001) which is similar to the in vitro results. There was no significant difference if the shock treatment was applied and left for 2 weeks or 4 weeks compared to the ones tested immediately after sacrifice. There were some soft tissue damage immediately following shock treatment in the focal area but this returned to normal in 2 weeks. Human cadaveric femoral bones and the canine bone (the dosage level was higher for the human bone than canine). The number of impacts used to extract the bone cement plug out of a human femur segment (5-cm long) decreased about 68% at 23 and 25 kV treatment power level. These preliminary studies indicate that the shock wave can be utilized to reduce the interfacial strength of the bone and bone cement although more studies are needed to assess its efficacy in terms of cost, long-term effect on patients and the exact mechanism of the loosening before this technique can be used clinically.
    Additional Material: 18 Ill.
    Type of Medium: Electronic Resource
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