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  • 11
    Electronic Resource
    Electronic Resource
    MEASUREMENT OF BLOOD-BRAIN BARRIER PERMEABILITY (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 17 (1990), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Experimental determinations of blood-brain barrier permeability from measurements of uptake of tracers by brain are limited in two ways. First, there are experimental limitations that are specific to the particular method being used. These limitations include the range of permeability values that a particular method can reliably determine (sensitivity); whether repeated experiments are possible in the same animal; whether regional values can be determined; and to what degree the chemical composition of the perfusate passing through the brain can be controlled.2. A second set of limitations on permeability determinations is of a more general, physiological nature. These constraints apply to a greater or lesser degree to all experimental determinations, and may limit the accuracy and reliability of the permeability values obtained; although certain reliable upper and lower bounds can be determined. These general factors include: capillary heterogeneity (i.e. variations in capillary lengths, surface areas, blood flows, etc.); the possibility of binding to circulating plasma proteins, especially albumin; and the possibility of capillary recruitment and de-recruitment with changes in cerebral blood flow.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1990.tb01286.x
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  • 12
    Electronic Resource
    Electronic Resource
    Physical properties of periodontal dressing materials (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 13 (1986), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The purpose of this study was to develop standardized reproducible testing methods for evaluating physical properties of periodontal dressing materials. Three commercial compositions (Coe-Pak, Coe-Pak Hard & Fast Set and WondrPak) were studied.Working and setting times were determined by observing the continuous changes in viscosity via the oscillating rheometer. The 24-h and 1-week tensile and shear adhesive bonds to enamel were studied by luting orthodontic lingual cleats with a standard film thickness to the orientated labial surfaces of extracted incisors and pulling them to failure. Dimensional change was studied over a period of 24h using a linear variable differential transformer (LVDT).The developed testing modalities have greater precision than those previously reported. The concept of ‘bench time’ was developed during which certain materials cannot be handled immediately after mixing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.1986.tb00681.x
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  • 13
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    An Experiment in Probability Estimation (1965)
    Chicago : Periodicals Archive Online (PAO)
    Journal of marketing research. 2:3 (1965:Aug.) 266 
    Details
    ISSN: 0022-2437
    Topics: Economics
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:b178-1965-002-03-000006
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  • 14
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    Canonical Analysis: An Exposition and Illustrative Application (1966)
    Chicago : Periodicals Archive Online (PAO)
    Journal of marketing research. 3:1 (1966:Feb.) 32 
    Details
    ISSN: 0022-2437
    Topics: Economics
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:b178-1966-003-01-000003
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  • 15
    Electronic Resource
    Electronic Resource
    Correlation of histometric, microbial, and clinical indicators of periodontal disease status before and after root planing (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 14 (1987), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Effective diagnosis and treatment of periodontal disease requires accurate evaluation of disease status before and after treatment. This study evaluated relationships among multiple parameters that have been used for periodontal disease evaluation. A total of 61 initially deep (≥6 mm) interproximal pockets from 16 patients examined before and after a 3-week course of root planing therapy were evaluated for probing depth, bleeding on probing, darkfield and cultural characterization of subgingival plaque, and histometric indices of infiltrated connective tissue (ICT) and mature plasma cell infiltrate. 36 sites were evaluated before treatment, and 25 after treatment. A comparison of mean scores for pre-treatment sites versus post-treatment sites indicated that there was an average improvement in most disease-related parameters. However, patterns of significant correlations among the parameters differed markedly. Motile bacteria enumerated by darkfield microscopy were significantly correlated with ICT and plasma-cell populations before, but not after treatment. In contrast, probing depth and populations of black pigmented Bacteroides (BPB's). principally B. gingivalis, were significantly correlated with ICT after, but not before, treatment. Bleeding on probing was not significantly correlated with ICT levels before or after treatment. This suggests that different sets of parameters should be used for evaluating periodontal disease status before or after treatment. Our data further suggest that B. gingivalis populations may be related to delayed healing of deep periodontal lesions after instrumentation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1987.tb00966.x
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  • 16
    Electronic Resource
    Electronic Resource
    MOLECULAR COMPLEXITY OF Qa-2 ANTIGENS DEMONSTRATED BY TWO-DIMENSIONAL GEL ELECTROPHORESIS (1987)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 14 (1987), S. 0 
    Details
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Biosynthetically labelled Qa-2 antigens were isolated from mouse spleen cells by immunoprecipitation with anti-Qa-2 antisera. When newly synthesized Qa-2 molecules from several different inbred strains were analysed by two-dimensional (2D) gel electrophoresis; four different phenotypes were observed that differed in the number of polypeptides present. The ability to distinguish Qa-2+ phenotypes was used to map the recombination points in two congenic strains, B6. Tlaa and A. Tlab. No alternative Qa-2-like polypeptides were detected in B6.K1 (Qa-2−) cells using a polyspecific rabbit antiserum against mouse class I antigens, but a new molecule was detected in BALB/cBy (Qa-2−) cells. Pulse-chase and surface-labelling experiments showed that some, but not all, of the newly synthesized Qa-2 precursor forms are processed to mature cell surface molecules.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-313X.1987.tb00366.x
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  • 17
    Electronic Resource
    Electronic Resource
    Identification of a population of mouse leukocytes using wheat germ agglutinin (1974)
    [s.l.] : Nature Publishing Group
    Nature 250 (1974), S. 517-517 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Cells teased from spleens of normal BALB/c mice were washed with Eagle's minimum essential medium containing 10% foetal bovine serum. Suspensions containing 107 cells ml?1 were treated with increasing concentrations of fluorescein-conjugated WGA and the number of labelled cells counted immediately ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/250517a0
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  • 18
    Electronic Resource
    Electronic Resource
    Pancreatitis: computed tomography and magnetic resonance imaging (2000)
    Springer
    European radiology 10 (2000), S. 401-408 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Computed tomography – Magnetic resonance imaging – Acute pancreatitis – Chronic pancreatitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The value of CT in management of severe acute pancreatitis is well established. Some, but not all, experimental studies suggest a detrimental effect of intravenous iodinated contrast agents in acute pancreatitis, but although initial clinical data tends to support this, the positive advantages of enhanced CT outweigh the possible risks. Magnetic resonance imaging has been shown to be as effective as CT in demonstrating the presence and extent of pancreatic necrosis and fluid collections, and probably superior in indicating the suitability of such collections for percutaneous drainage. Image-guided intervention remains a key approach in the management of severely ill patients, and the indications, techniques and results of radiological intervention are reviewed herein. Both CT and MRI can be used to diagnose advanced chronic pancreatitis, with the recent addition of MRCP as a viable alternative to diagnostic endoscopic retrograde cholangiopancreatography (ERCP). Both MRCP and CT/MR imaging of the pancreatic parenchyma still have limitations in the recognition of the earliest changes of chronic pancreatitis – for which ERCP and tests of pancreatic function remain more sensitive – but the clinical significance of these minor changes remains contentious.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050066
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  • 19
    Electronic Resource
    Electronic Resource
    Assessment of resectability of pancreatic cancer with dynamic contrast-enhanced MR imaging: technique, surgical correlation and patient outcome (1998)
    Springer
    European radiology 8 (1998), S. 23-29 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Pancreatic cancer ; MRI ; Contrast media
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The aim of our work was to investigate the use of a dynamic contrast-enhanced MR (DCEMR) technique for staging apparently localised pancreatic cancer, and to determine the patterns of tumour and vascular enhancement with this technique. Thirty-five consecutive patients were examined. The MR findings were correlated with surgical findings in 13 patients and with clinical outcome in 22 patients. Breath-hold gradient-echo fast low angle shot (TR = 100, TE = 4, flip angle 80 °) acquisitions were obtained at 10 and 40 s (right anterior coronal oblique plane) and at 90 s (axial plane) following intravenous gadolinium. Mean contrast-to-noise ratio was higher on the first than the second acquisition (p 〈 0.001) and higher on the second acquisition than the third (p 〈 0.005). Tumour conspicuity was greatest and arterial anatomy was best demonstrated on the first acquisition and the portal venous anatomy on the second. Small tumours were isointense by the third acquisition. Maximal intensity projections were helpful. The MR findings correctly predicted the surgical findings in 11 of 13 cases (85 %) and the clinical course in the other 22 patients. The DCEMR imaging technique is valuable in the staging of patients with pancreatic cancer. Capillary and portal venous phase images are both required for complete local staging.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050331
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  • 20
    Electronic Resource
    Electronic Resource
    Pseudolipoma of inverted Meckel's diverticulum: clinical, radiological and pathological correlation (1997)
    Springer
    European radiology 7 (1997), S. 900-904 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Inverted Meckel's diverticulum ; Lipoma ; Small bowel ; Radiology ; Ultrasonography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Three cases of isolated inverted Meckel's diverticulum are described. In two cases an initial pathological diagnosis of small bowel lipoma was suggested. In a third case central fat was demonstrated on CT and peristalsis of the intraluminal polypoid mass was observed during US examination. In all three cases small bowel enema examination demonstrated the lesion. Correlation of the clinical, radiological and pathological features is emphasised, as this will allow the correct diagnosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050224
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