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  • 11
    Electronic Resource
    Electronic Resource
    Effect of age on the pharmacokinetics of vinpocetine (Cavinton) and apovincaminic acid (1987)
    Springer
    European journal of clinical pharmacology 33 (1987), S. 185-189 
    Details
    ISSN: 1432-1041
    Keywords: vinpocetine ; apovincaminic acid ; healthy volunteers ; elderly subjects ; pharmacokinetics ; age effect
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of vinpocetine and its main metabolite, apovincaminic acid (AVA), were studied in the aged. Vinpocetine was eliminated with a mean half-life of 2.12±0.51 h. Total plasma clearance (CL) and distribution coefficient (Δ) of the parent drug were 2.2±0.9 l · kg−1 · h−1 and 6.7±3.7 l · kg−1, respectively. The CL and Δ of vinpocetine differed significantly from young subjects but the elimination half-life was not altered. Significant changes in the elimination half-life and plasma clearance of AVA were found, perhaps because of the physiological decrease in renal function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00544565
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  • 12
    Electronic Resource
    Electronic Resource
    Renal sodium reabsorption and oxygen consumption after unilateral splanchnicotomy in the dog (1974)
    Springer
    Pflügers Archiv 349 (1974), S. 359-367 
    Details
    ISSN: 1432-2013
    Keywords: Renal Denervation ; Oxygen Consumption ; Furosemide ; Na Transport
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Experiments were carried out on pentobarbital-anaesthetized dogs previously subjected to unilateral splanchnicotomy. Renal blood flow (RBF), glomerular filtration rate (GFR), tubular reabsorption of sodium (TRFNa), and oxygen consumption (Q O 2) were determined in normal state, following isotonic volume expansion and during furosemide administration (0.5–1.5 mg/kg bw.). Denervation diuresis and natriuresis occurred under all experimental conditions. TRFNa/Q O 2 was 31.4 mEq/mMol for intact and 27.7 mEq/mMol for denervated kidneys in the normal and isotonic volume expanded dogs. These values decreased significantly to 16.8 mEq/mMol and 18.3 mEq/mMol, respectively, upon furosemide loading. No difference between intact and denervated kidneys was observed in either group. TRFNa, RBF, and GFR were significantly correlated toQ O 2 with no difference between intact and splanchnicotomized sides. An inhibitory effect of renal denervation on active sodium transport in the proximal tubule is suggested.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588421
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  • 13
    Electronic Resource
    Electronic Resource
    Early secondary corrections after septorhinoplasty (2004)
    Springer
    Aesthetic plastic surgery 20 (2004), S. 429-432 
    Details
    ISSN: 1432-5241
    Keywords: Septorhinoplasty ; Secondary corrections
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We perform all secondary corrections after septorhinoplasty as early as possible. Ten or twelve days after the primary intervention, the edema has diminished to such an extent that any residual defect is clearly detectable and easy to correct. This essentially is the concept of early secondary corrections after septorhinoplasty. We are convinced that any type of secondary correction can be performed at an early time. Our experience shows with an early secondary correction, patient and surgeon alike avoid the stress of a long waiting period as well as patient dissatisfaction during this waiting time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00210864
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  • 14
    Electronic Resource
    Electronic Resource
    Early secondary corrections after septorhinoplasty (1996)
    Springer
    Aesthetic plastic surgery 20 (1996), S. 429-432 
    Details
    ISSN: 1432-5241
    Keywords: Septorhinoplasty ; Secondary corrections
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We perform all secondary corrections after septorhinoplasty as early as possible. Ten or twelve days after the primary intervention, the edema has diminished to such an extent that any residual defect is clearly detectable and easy to correct. This essentially is the concept of early secondary corrections after septorhinoplasty. We are convinced that any type of secondary correction can be performed at an early time. Our experience shows with an early secondary correction, patient and surgeon alike avoid the stress of a long waiting period as well as patient dissatisfaction during this waiting time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02390319
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  • 15
    Electronic Resource
    Electronic Resource
    Transfer of electronic excitation energy in mixed solutions of carotenoids and chlorophylls (1973)
    Springer
    Journal of applied spectroscopy 19 (1973), S. 1135-1137 
    Details
    ISSN: 1573-8647
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00614571
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  • 16
    Electronic Resource
    Electronic Resource
    Über die wassermilben (hydrachnellae) der hohen tatra (=Vysoké Tatry) (1956)
    Springer
    Hydrobiologia 8 (1956), S. 155-180 
    Details
    ISSN: 1573-5117
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00047484
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  • 17
    Electronic Resource
    Electronic Resource
    Effects of chronic renal denervation in conscious restrained rats (1986)
    Springer
    International urology and nephrology 18 (1986), S. 3-18 
    Details
    ISSN: 1573-2584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sodium (Na), calcium (Ca), inorganic phosphate (Pi) and water excretion were measured in nondiuretic (ND) and extracellular fluid (ECF) volume expanded (VE) conscious restrained rats four weeks after denervation or sham-denervation of the left kidney. On the day of the study the animals were lightly anaesthetized with ether and the femoral vessels on one side were catheterized. Urine was collected from both kidneys. The animals were allowed to recover for 3 hours and studied in a restraining chamber. In ND animals isotonic saline containing inulin and para-amino-hippuric acid (PAH) were given at a rate of 0.067±0.002 (SE) ml/min/kg body weight (BW). In VE animals the infusion rate was 0.24±0.04 ml/min/kg BW. Kidney catecholamine content was measured after the experiments. Clearances of PAH and of inulin (GFR) were the same in both kidneys. Urine volume (V), sodium excretion (UNaV/GFR), inorganic phosphate excretion (UPiV/GFR) and calcium excretion (UCaV/GFR) were significantly higher in the denervated kidneys. Values in sham denervated kidneys were not greater than those of the right kidney. Denervation was proven by demonstrating absent or very low catecholamine content in the kidneys. The results demonstrate that: (a) chronic renal denervation in rats leads to diuresis and natriuresis even in the conscious state, thus confirming previous results from our laboratory; (b) such changes occur independently of the state of the ECF volume and of renal haemodynamic changes; (c) the increased excretion of Ca++ and Pi after denervation demonstrates that renal nerves affect the reabsorption of these ions either independently or by way of their effect on sodium reabsorption. These data allow us to suggest that a renal tubular dysfunction, which was proved in anaesthetized denervated animals, can also be observed in the conscious state.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02082643
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  • 18
    Electronic Resource
    Electronic Resource
    Book reviews (1986)
    Springer
    International urology and nephrology 18 (1986), S. 357-362 
    Details
    ISSN: 1573-2584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02082726
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  • 19
    Electronic Resource
    Electronic Resource
    Construction of a neoclitoris in the surgery of male transsexuals (1992)
    Springer
    European journal of plastic surgery 15 (1992), S. 192-193 
    Details
    ISSN: 1435-0130
    Keywords: Glans penis ; Neoclitoris ; Transsexualism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To preserve the ability of male transsexuals who have been operated on to have orgasms, the glans penis and the corpus cavernosum urethrae are retained as a unit. The main vessels of the glans penis, the dorsal artery and vein of the penis running in the deep fascia of the penis are utilized as the neurovascular pedicle. The glans penis is placed into the anterior wall of the neovagina under the symphysis as the neoclitoris.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00660510
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  • 20
    Electronic Resource
    Electronic Resource
    Plasma expander for use to fill inflatable implants (1994)
    Springer
    European journal of plastic surgery 17 (1994), S. 50-50 
    Details
    ISSN: 1435-0130
    Keywords: Plasma expander ; Breast implants
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To prevent volume loss of inflatable breast implants through osmosis, I have been using plasma-expander instead of saline to fill the implants over the last four years.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00176507
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