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  • 31
    Publication Date: 2020-08-05
    Description: We prove a mathematical programming characterisation of approximate partial D-optimality under general linear constraints. We use this characterisation with a branch-and-bound method to compute a list of all exact D-optimal designs for estimating a pair of treatment contrasts in the presence of a nuisance time trend up to the size of 24 consecutive trials.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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  • 32
    Publication Date: 2020-08-05
    Description: We introduce the class of spot-checking games (SC games). These games model problems where the goal is to distribute fare inspectors over a toll network. Although SC games are not zero-sum, we show that a Nash equilibrium can be computed by linear programming. The computation of a strong Stackelberg equilibrium is more relevant for this problem, but we show that this is NP-hard. However, we give some bounds on the \emph{price of spite}, which measures how the payoff of the inspector degrades when committing to a Nash equilibrium. Finally, we demonstrate the quality of these bounds for a real-world application, namely the enforcement of a truck toll on German motorways.
    Language: English
    Type: conferenceobject , doc-type:conferenceObject
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  • 33
    Publication Date: 2020-08-05
    Description: We introduce the class of spot-checking games (SC games). These games model problems where the goal is to distribute fare inspectors over a toll network. Although SC games are not zero-sum, we show that a Nash equilibrium can be computed by linear programming. The computation of a strong Stackelberg equilibrium is more relevant for this problem, but we show that this is NP-hard. However, we give some bounds on the \emph{price of spite}, which measures how the payoff of the inspector degrades when committing to a Nash equilibrium. Finally, we demonstrate the quality of these bounds for a real-world application, namely the enforcement of a truck toll on German motorways.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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  • 34
    Publication Date: 2020-08-05
    Description: Model-based optimal design of experiments (M-bODE) is a crucial step in model parametrization since it encloses a framework that maximizes the amount of information extracted from a battery of lab experiments. We address the design of M-bODE for dynamic models considering a continuous representation of the design. We use Semidefinite Programming (SDP) to derive robust minmax formulations for nonlinear models, and extend the formulations to other criteria. The approaches are demonstrated for a CSTR where a two-step reaction occurs.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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  • 35
    Publication Date: 2020-08-05
    Description: We present the problem of planning mobile tours of inspectors on German motorways to enforce the payment of the toll for heavy good trucks. This is a special type of vehicle routing problem with the objective to conduct as good inspections as possible on the complete network. In addition, we developed a personalized crew rostering model, to schedule the crews of the tours. The planning of daily tours and the rostering are combined in a novel integrated approach and formulated as a complex and large scale Integer Program. The main focus of this paper extends our previous publications on how different requirements for the rostering can be modeled in detail. The second focus is on a bi-criteria analysis of the planning problem to find the balance between the control quality and the roster acceptance. Finally, computational results on real-world instances show the practicability of our method and how different input parameters influence the problem complexity.
    Language: English
    Type: article , doc-type:article
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  • 36
    Publication Date: 2020-08-05
    Description: The problem of allocating operating rooms (OR) to surgical cases is a challenging task, involving both combinatorial aspects and uncertainty handling. We formulate this problem as a parallel machines scheduling problem, in which job durations follow a lognormal distribution, and a fixed assignment of jobs to machines must be computed. We propose a cutting-plane approach to solve the robust counterpart of this optimization problem. To this end, we develop an algorithm based on fixed-point iterations that identifies worst-case scenarios and generates cut inequalities. The main result of this article uses Hilbert's projective geometry to prove the convergence of this procedure under mild conditions. We also propose two exact solution methods for a similar problem, but with a polyhedral uncertainty set, for which only approximation approaches were known. Our model can be extended to balance the load over several planning periods in a rolling horizon. We present extensive numerical experiments for instances based on real data from a major hospital in Berlin. In particular, we find that: (i) our approach performs well compared to a previous model that ignored the distribution of case durations; (ii) compared to an alternative stochastic programming approach, robust optimization yields solutions that are more robust against uncertainty, at a small price in terms of average cost; (iii) the \emph{longest expected processing time first} (LEPT) heuristic performs well and efficiently protects against extreme scenarios, but only if a good prediction model for the durations is available. Finally, we draw a number of managerial implications from these observations.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
    Format: application/pdf
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  • 37
    Publication Date: 2020-08-05
    Description: Let G be a directed acyclic graph with n arcs, a source s and a sink t. We introduce the cone K of flow matrices, which is a polyhedral cone generated by the matrices $\vec{1}_P\vec{1}_P^T\in\RR^{n\times n}$, where $\vec{1}_P\in\RR^n$ is the incidence vector of the (s,t)-path P. We show that several hard flow (or path) optimization problems, that cannot be solved by using the standard arc-representation of a flow, reduce to a linear optimization problem over $\mathcal{K}$. This cone is intractable: we prove that the membership problem associated to $\mathcal{K}$ is NP-complete. However, the affine hull of this cone admits a nice description, and we give an algorithm which computes in polynomial-time the decomposition of a matrix $X\in \operatorname{span} \mathcal{K}$ as a linear combination of some $\vec{1}_P\vec{1}_P^T$'s. Then, we provide two convergent approximation hierarchies, one of them based on a completely positive representation of~K. We illustrate this approach by computing bounds for the quadratic shortest path problem, as well as a maximum flow problem with pairwise arc-capacities.
    Language: English
    Type: article , doc-type:article
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  • 38
    Publication Date: 2020-08-05
    Description: We show that the A-optimal design optimization problem over m design points in R^n is equivalent to minimizing a quadratic function plus a group lasso sparsity inducing term over n x m real matrices. This observation allows to describe several new algorithms for A-optimal design based on splitting and block coordinate decomposition. These techniques are well known and proved powerful to treat large scale problems in machine learning and signal processing communities. The proposed algorithms come with rigorous convergence guarantees and convergence rate estimate stemming from the optimization literature. Performances are illustrated on synthetic benchmarks and compared to existing methods for solving the optimal design problem.
    Language: English
    Type: article , doc-type:article
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  • 39
    Publication Date: 2021-09-29
    Description: A design point is inessential when it does not contribute to an optimal design, and can therefore be safely discarded from the design space. We derive three inequalities for the detection of such inessential points in c-optimal design: the first two are direct consequences of the equivalence theorem for c-optimality; the third one is derived from a second-order cone programming formulation of c-optimal design. Elimination rules for A-optimal design are obtained as a byproduct. When implemented within an optimization algorithm, each inequality gives a screening test that may provide a substantial acceleration by reducing the size of the problem online. Several examples are presented with a multiplicative algorithm to illustrate the effectiveness of the approach.
    Language: English
    Type: article , doc-type:article
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  • 40
    Publication Date: 2020-08-05
    Language: English
    Type: article , doc-type:article
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