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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of social welfare 6 (1997), S. 0 
    ISSN: 1468-2397
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Sociology
    Notes: The objective of the study was to investigate whether intensified rehabilitation efforts in primary health care may produce any short-term or long-term reduction of sick leave. The resources at the health care center were fortified with a coordinator from the local insurance office and a specialist group from the hospital. In one primary health care district, a prospective study was performed among 100 patients with a musculoskeletal disorder, having caused at least 21 consecutive days of full-time sick leave (patients). Serving as a control group were individually matched patients from any other health care center in the surrounding municipality of Kristianstad (controls). The number of sick leave days was assessed during year one (short-term) and year three (long-term) after rehabilitation was initiated. The median number of days with sickness benefits for men in the short-term was lower for patients than for controls (34.5 vs 48.5). No difference was found among women. No differences were found in the long-term between patients and controls, either for men or women. We conclude that rehabilitation in primary health care was made more efficient through collaboration with the local insurance office and the specialists, but the effects were not maintained after the collaboration ended.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The production of cytokines from T cells and macrophages is of potential importance for the histological changes apparent in coeliac disease (CoD). Small intestinal biopsy specimens from children with CoD and disease control subjects were investigated for their content of cytokines and tissue transglutaminase (tTG). The transforming growth factor-β1 (TGF-β1) expression was increased in the lamina propria of children with villous atrophy. In contrast, TGF-β3 was expressed at a higher level in the epithelium and the lamina propria of the disease control subjects. The tTG expression was increased in the small intestine of CoD patients as compared with that in subjects. Interleukin-4 (IL-4) was detected in the lamina propria of both CoD patients and controls, and some of the investigated biopsy specimens also showed IL-4 expression in the epithelium. We conclude that children with active CoD could have an altered expression of TGF-β and tTG in the small intestine and that a disturbed regulation of TGF-β may be of importance in the immune pathogenesis of CoD.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Immune-mediated food hypersensitivity affecting the gut is difficult to evaluate, and objective tools to diagnose local gastrointestinal (GI) inflammatory reactions are lacking.Objectives To determine whether allergic manifestations in adults with a history of food-related GI symptoms could be assessed in feces during symptomatic and non-symptomatic periods, using the surrogate markers, eosinophil cationic protein (ECP), eosinophil protein X (EPX) and myeloperoxidase (MPO).Methods Thirteen subjects with food hypersensitivity-related GI symptoms, confirmed by a positive double-blind placebo-controlled food challenge (DBPCFC), were subjected to an open kinetic food challenge design for 6 weeks. Symptoms were recorded and scored during the 3-week study period and stool samples were obtained every day. The surrogate markers ECP, EPX and MPO were measured in the supernatants from feces samples.Results A significant increase in abdominal pain, distension and flatulence was observed during challenge, with a gradual decrease during elimination diet. Both between days and subjects, EPX levels were more frequently increased compared to ECP and MPO. Individuals with a history of a short duration of symptoms had significantly higher mean levels of EPX and MPO than those with a longer duration of symptoms.Conclusions An overall increase in levels of eosinophil markers, in particular EPX, was observed in feces from patients with food-related GI symptoms. However, rather than being a tool to differentiate symptomatic from non-symptomatic periods, EPX might be used for detecting an ongoing clinical or subclinical chronic inflammation, that may have an impact on the patient's clinical course of GI symptoms.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    PO Box 1354, 9600 Garsington Road, Oxford OX4 2XG, UK. : Blackwell Science Ltd
    Fatigue & fracture of engineering materials & structures 28 (2005), S. 0 
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Fatigue crack propagation in circular Ti–6Al–4V specimens subjected to high strain amplitudes has been investigated. Crack closure was measured with an electrical potential-drop technique. Closure was shown not to depend on strain ratio but to be a function of the applied strain range. At higher strain ranges, the crack was found to be closed for a smaller part of the load cycle than at lower strain ranges due to blunting of the crack tip. Furthermore, the use of a strain-intensity approach to predict crack-propagation rate was investigated, and it was found that for the upper parts of the da/dN curves the effective strain intensity yields good predictions. Also, the effective stress-intensity factor was found to collapse the da/dN curves for different load ratios.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    PO Box 1354, 9600 Garsington Road, Oxford OX4 2XG, UK. : Blackwell Science Ltd
    Fatigue & fracture of engineering materials & structures 27 (2004), S. 0 
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The influence of choice of constitutive relation on the prediction of crack-opening stress for fatigue cracks using the finite-element method is investigated and compared with experimental results. Two different experimentally obtained stress–strain relations for IN718 at 550 °C were used for fitting material parameters to the linear kinematic and the Bodner–Partom viscoplastic constitutive models. In addition, one reference material description and one Bodner–Partom with parameters fitted to both types of experiment was used, i.e., in total six constitutive descriptions. Experimental values for crack-opening stress were found by the potential drop method for the two load cases analyzed. Two different load cases, load control and displacement control, have been examined. It turns out that the correlation between experimental and analytical crack-opening stress vary significantly with material description, opening criteria in the simulation and load case. The investigation shows that care must be taken when choosing material description and opening criteria for crack propagation simulations.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In the comparison of radiographical findings (flattening, irregular surface and osteophyte formation) between lateral tomography and Orthopantomography(r) in thirty-one female patients with craniomandibular disorders, a 76% similarity was found. A trend in the findings was seen: with an increase in radiographical findings visible in the tomograms there is a decrease in the amount of condylar asymmetry visible in the Orthopantomograms(r) and a decrease in the age of the patients.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 16 (1989), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Maxillary full-arch splints in the retruded position (RP) and in a right lateral occlusion (1.0- 1.5 mm to the right of the retruded contact position) were fabricated for ten subjects. Surface electromyography of the masseter and anterior temporal muscles was performed during submaximal clenching in order to investigate the immediate effects of the splints on the activity patterns of these muscles relative to the patterns found with the subjects occlusion in the inter-cuspal position. The splints in the RP were found to have no effect on the asymmetry of the activity of the masseter and the anterior temporal muscles, while the splints in a right lateral occlusion resulted in relative increases in right anterior temporal muscle activity (P〈0.005).
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A comparison between clinical, tomographical, and dental panoramic radiographical findings was made in thirty-one female patients suffering from craniomandibular disorders (CMD). In general it was found that condylar sclerosis was more common in these patients than in earlier studies. After clinical separation of the material into two groups based upon the origin of pain, myogenous versus arthrogenous, no radiographical confirmation of the differential diagnostics could be made. Regarding vertical condylar asymmetry measured on the Orthopantomogram®, it was found that 74% of the patients with CMD had more than the 3% of asymmetry regarded as within normal limits. It seems that with an increasing severity of the disorder the level of condylar asymmetry appears less. If the interpretation of the findings is correct its conclusion might lead to the recognition of a morphological factor which could contribute to the development of a craniomandibular disorder.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A comparison has been made between clinical and radiographical findings in a study of eighty-nine patients suffering from craniomandibular disorders. In general it was found that condylar changes were more common in these patients than in earlier studies concerning the severe problems of craniomandibular disorders. A statistically significant correlation between clinical and radiographical findings was found for crepitation with osteophyte formation of the condyle (P〈0.01). After clinical separation of the patients into two groups based upon the origin of pain, myogenous versus arthrogenous, no radiographical correlation could be made except for condylar osteophytes. With the clinical method used for separation of patients it was found that the clicking of the temporomandibular joint (TMJ) was more common among myogenous patients (P〈0.05); crepitation was more common among arthrogenous patients (P〈0.01), as was limited mouth opening (P〈0.05) and deviation on opening (P〈0.05). Radiographically, the only statistical difference between the two groups was found for osteophyte formation of the condyle, this was more common among arthrogenous patients (P〈0.05). As the clinical method has been tested earlier, the results of this study lends support to the idea that conventional radiographical examination is of limited use in the initial diagnostics of craniomandibular disorders. Therefore new alternatives have to be developed.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 13 (1986), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Sixty patients, clinically examined for TMJ dysfunction, were also electromyographically screened. The TMJ dysfunction pain in forty patients was evaluated to be mainly of a myogenous origin and in fourteen patients of a mainly arthrogenous origin. Due to lack of findings in the clinical examination six patients were not to be classified into either of the two groups. They were excluded from the EMG study. For the EMG examination the patients were asked to clench for 30 s in the intercuspal position at 50% of the maximum EMG activity of the masseter muscles. Surface electromyograms of the right and the left masseter and anterior part of the temporalis muscles were monitored. The amplitude of the EMG signal, the duration of the silent period and the changes in the frequency composition of the signal during the 30 s contraction were analysed.Statistically significant differences between the two patient groups were found in EMG amplitude and in silent period duration. However, the difference in silent period duration was due to the dependency of the silent period on the activation level of the muscle. No statistically significant difference in silent period was found when this dependency was corrected for in the data. The EMG parameters related to muscular fatigue phenomena did not show any difference between the two groups.The difference in EMG amplitude and consequently the difference in silent period duration support the clinically made distinction into mainly a myogenous or mainly an arthrogenous origin of TMJ dysfunction pain.
    Type of Medium: Electronic Resource
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