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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 103 (1996), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Plant pathology 46 (1997), S. 0 
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Samples of maize seed were obtained from countries in Central America, Africa and Asia and assessed for fungal infection. Fusarium spp. were the largest single group of fungi present, and from these Fusarium moniliforme was the species most frequently isolated. Other fungi, including Stenocarpella (Diplodia) maydis, S. macrospora and Acremonium strictum, were also present in significant numbers. Isolates of F. moniliforme were characterized for mating populations, using RAPDs, and a number of isolates, taken at random from those assigned to specific mating groups, were also confirmed by crossing. Isolates were also characterized for fusaric acid production and significant differences in fusaric acid production were detected between isolates from different countries and regions within countries. A detailed analysis of isolates from one country, Kenya, was undertaken. The importance of the pathogens is discussed in relation to human, animal and seed health and quarantine regulations, and plant breeding objectives.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: As many as 50% of patients with reflux symptoms have no endoscopic evidence of oesophagitis. This multicentre study was designed to assess symptom relief after omeprazole 20 mg once daily in patients with symptoms typical of gastro-oesophageal reflux disease but without endoscopic evidence of oesophagitis. Methods: Patients (n=209) were randomized in a double-blind study to receive either omeprazole 20 mg once daily (n=98) or placebo (n=111) for 4 weeks. Symptoms were assessed at clinic visits and using daily diary cards, with patient-completed questionnaires providing additional data on symptoms and on psychological disturbance. Results: On completion, symptom relief favoured omeprazole: 57% of patients on omeprazole were free of heartburn (vs. 19% on placebo), 75% were free of regurgitation (47%) and 43% were completely asymptomatic (14%), each with P〈0.0001. Fewer patients in the omeprazole group required alginate/antacid relief medication (P〈0.05). Symptom relief (time to first heartburn-free day) was more rapid with omeprazole (2 vs. 5 days on placebo; P〈0.01). A greater reduction in anxiety occurred in the omeprazole group (P〈0.05). Conclusion: Omeprazole 20 mg once daily is effective in providing relief of the symptoms typical of gastro-oesophageal reflux disease in patients with essentially normal oesophageal mucosa.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 104 (1997), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 60 (1995), S. 3020-3027 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Restoration ecology 3 (1995), S. 0 
    ISSN: 1526-100X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: We conducted an experiment with the dual aims of (1) examining the feasibility of establishing a species-rich grassland using a commercially available grass and wild-flower seed mixture and (2) examining the effects of different defoliation and fertilizer managements on the productivity, species richness, diversity, and composition of a species-rich grassland established on a site reclaimed after opencast coal mining. The use of the seed mixture successfully established a sward of some 18–25 species per square meter. The species composition was enriched to some extent by recruitment of unsown species, principally from the soil seed bank. Hay-type defoliation management produced greater dry matter yield and species richness than grazing defoliation, but grazing defoliation produced greater species diversity. Fertilizer application had no significant effect on dry matter production but reduced species diversity. Ordination analysis revealed that both defoliation and fertilizer management significantly affected species composition. The response obtained by individual species was explicable largely by their comparative biology.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Restoration ecology 4 (1996), S. 0 
    ISSN: 1526-100X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Aggressive growth by legumes may restrict the diversity of species-rich meadows recreated on sites restored after mineral extraction. We investigated the ability of mineral nitrogen (N) applications and spring grazing to control the legume component of such meadows. The use of N suppressed Trifolium repens but had no effect on other legume species or on the species richness, diversity, or equitability of the meadow community. Spring grazing significantly reduced the yield from the legume component of the meadow. This was accompanied by an increase in the equitability index of the community, suggesting that the aggressive nature of the legumes had been checked. Spring grazing may therefore provide a means of controlling aggressive legume growth and may maintain the diversity of species-rich meadows established on restored sites.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford BSL : Blackwell Science
    Alimentary pharmacology & therapeutics 11 (1997), S. 0 
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by a progressive obliterating fibrosis of the intrahepatic and extrahepatic bile ducts. The pathogenesis of PSC is poorly understood but it is thought to be an immune-mediated disease. The optimal therapy which successfully improves symptoms, delays progression towards liver failure and transplantation and prevents the onset of cholangiocarcinoma remains elusive. Although current treatments are used to manage cholestasis and its consequences and some of the more general complications of the disease, none of the current therapeutic agents have been shown to retard and reverse the rate of disease progression. The role of cupruretics, corticosteroids, methotrexate, anti-fibrogenic agents and ursodeoxycholic acid in the treatment of PSC is reviewed. Orthotopic liver transplantation remains the only therapeutic option for advanced PSC but the timing of transplantation remains controversial and the possibility of recurrence of the disease in the graft is increasingly recognised. It is likely that greater insight into the pathogenetic mechanisms involved in PSC will allow therapy to be targetted more specifically at the biliary epithelium.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The wreckfish Polyprion americanus, a large [〉1 m total length (LT)] demersal teleost, is distributed globally in temperate waters, including both sides of the North and South Atlantic Oceans, the Mediterranean, the western South Pacific, and the southern Indian Ocean. Wreckfish spawn off the south-eastern U.S. on an area of the Blake Plateau (the Charleston Bump) characterized by an extensive ridge having approximately 100 m relief, in 450–600 m depths. Juvenile wreckfish (〈60 cm LT) are pelagic and, in the North Atlantic, are not reported from the Blake Plateau fishing area, but occur in by-catch and fishery landings in the eastern Atlantic. Analysis of nine restriction fragment length profiles from a PCR-amplified fragment (∼1.5 kb) of the ND1 mitochondrial gene indicated no stock separation between eastern North Atlantic (Azores, Majorca, Madeira), and western North Atlantic (Blake Plateau) wreckfish. Restriction site differences separate western South Atlantic wreckfish from the North Atlantic; however, South Atlantic wreckfish share restriction-site similarities with western Pacific wreckfish that are not shared with North Atlantic wreckfish. North Atlantic circulation provides a mechanism for a long-lived pelagic stage to be dispersed from Blake Plateau spawning grounds to the eastern North Atlantic. Global circulation patterns may explain both the dispersal of mtDNA haplotypes and the disjunct distribution of wreckfish body lengths in a temperate, deep-water vagile species with an extended pelagic juvenile stage such as wreckfish.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 51 (1996), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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