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  • 1
    Electronic Resource
    Electronic Resource
    A new type of multiparticle imaging detector (1990)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 61 (1990), S. 945-952 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The foil-induced dissociation of molecular ions can provide a direct image of the stereochemical structures of small molecules. Such experiments require high-resolution measurements of the relative momenta of all dissociation fragments. In order to improve and extend previous studies of this type to a larger variety of molecules and clusters, we have developed a new type of low-pressure multiwire proportional counter. The novel feature of this large-area (25×50 cm2 ) multiparticle detector is that all the signals are recorded from a single two-level printed circuit board which serves as the anode. This segmented anode consists of three families of nonintersecting "wires'' which are interwoven on the rear surface of the board. By redundantly determining positions and arrival times, the new segmented anode multiparticle detector provides good time resolution (100–200 ps) and high spatial resolution (0.2 mm) for detecting as many as six simultaneous particles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1141447
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  • 2
    Electronic Resource
    Electronic Resource
    Intersubband absorption in a modulation-doped Ga0.47In0.53As/Al0.48In0.52As multiple quantum well structure (1988)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 53 (1988), S. 571-573 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We observe strong intersubband absorption at a wavelength of 8.4 μm in an n-type modulation-doped Ga0.47In0.53As/Al0.48In0.52As multiple quantum well structure with a well thickness of 8.2 nm. An oscillator strength of the corresponding dipole transition of 21.0 is measured. The dependence of the intersubband absorption on the polarization of the incident light and on lattice temperature is investigated in detail.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.99860
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  • 3
    Electronic Resource
    Electronic Resource
    The allergens of nail polish (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 33 (1995), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Nail polish that has completely dried on the fingernails contains water-soluble components that attain the skin during extensive but transient contact. This was proven by water extraction of thin layers of nail polish that had been painted onto glass plates and allowed to dry for 3 days. Comparing the isolated fractions and compounds with known nail polish ingredients revealed that the water-soluble substances are para- and ortho-toluenesulfonamide. Dihuty1 phthalate and 3 constituents of toluenesulfonamide-formaldehyde resin (TS-F-R), which is the basic material of almost all nail polishes sold worldwide. 12 female patients with proven nail polish allergy were patch tested with 21 nail polish components, including those isolated. Only 2 fractions were positive. These contained a monomer and a dimer created during condensation of TS-F-R. Their structures were elucidated. The 3rd compound, a trimer, remained negative, except in 1 case.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1995.tb00537.x
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  • 4
    Electronic Resource
    Electronic Resource
    Structure-activity relationships in allergic contact dermatitis (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 33 (1995), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Primin (2-methoxy-6-pentyl-1,4-benzoquinone)is a naturally-occurring strong sensitizer from Primula obconica (Primulaceae), To determine the effect of side-chain length on senstizing potency 15 analogues with linear side chains from to from C1, to C15 and 4 C6- analogues with branched side chains were prepared synthetically and devoted to experimental sensitization in guinea pigs The results showed an increase of the sensitizing capacity with increasing length of the alkyl side chain from C1 to C10, reaching a maximum at C11 and C12. On further elongation the senstizing potency decreased beyond C13 reaching values which finally were as low as those of the C1 and C3 derivatives. The results mirror finding which finally were as low as those of the C1 and C3 derivatives. The results mirror findings which formerly have been obtained with other non-quinonoid compounds like catechols, phenols hydroquinones and gallates. In the plant kingdom. Compound approximating an “ideal allergen” consisting of a quinonoid ring with a 10 or 11 carbon-remarkably strong sensitizer found in Wigandia caracasana (Hydrophyllaceae)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1995.tb00440.x
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  • 5
    Electronic Resource
    Electronic Resource
    New hydroxyisoflavans as contact sensitizers in cocus wood Brya ebenus DC (Fabaceae) (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 25 (1991), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 15-year-old girl developed perioral dermatitis and swelling of the lips, having played a flute made of cocus wood for 2 years. Patch tests with wood shavings, as well as with subsequently isolated constituents named focus 1 and focus II. were Strongly positive. Alter complete purification, boltContact allergens were identified as isoflavan derivatives, While Cocus 1 was shown to be 7,8-dihydroxy-2,4,5trmethoxyisoflava, the structure of focus II could not be elucidated exactly. It could have been Either 7,8,3′-trihydroxy 2,4 dimethoxyisoflavan or 7,8,2-trihydroxy-3′,4-dime-thoxyoflavan The exact position of the hydroxy and methoxy group in C-2 and C-3 can be determined only by complete synthesis Of both compounds or by isolation of greater amounts of focus II for further oxidation experiments. Due t0 the stronger patch lest reaction and the higher yield cocus I in the wood, this hydroxyisoflavan must be recognized as the main contact allergen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1991.tb01820.x
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  • 6
    Electronic Resource
    Electronic Resource
    Contact allergy due to colophony (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 20 (1989), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 7 resin acids, 3 symbolically prepared derivatives and the neutral fraction of Chinese colophony were studied by experimental sensitization using a modified FCA method. 4 resin acids, laevopimaric. abietic. podocarpic and tetrahydroabietic. proved to be weak sensitizers Neoabietic, dehydroabietic, isopimarie acid and larixol remained negative. However, the derivative, methyl abietate and calcium abietate. were shown to be moderate sensitizers. and the maleic-modified adduct to be a moderate to strong sensitizer. As laevopimaric acid plays only a minor rote in colophony, abietic acid must he considered a major, even if weak, allergen in non-modified colophony. The neutral fraction of colophony is also partially involved in colophony allergy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1989.tb03094.x
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  • 7
    Electronic Resource
    Electronic Resource
    Release and Functional Characterization of the Leukotriene D4-Metabolizing Enzyme (Dipeptidase) from Human Polymorphonuclear Leucocytes (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 25 (1987), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Polymorphonuclear leucocytes released LTD4-dipeptidase activity in a time-, calcium-, and cell number-dependent fashion. The LTD4-dipeptidase released from polymorphonuclear leucocytes (PMN) by incubation with calcium (0.91 mm) was detectable up to a cell concentration of 1 × 106/ml and increased with higher concentrations. Maximal LTD4-dipeptidase activity within the extracellular environment was detected after 15 min of incubation (2x107/ml) in the presence of 2–4.5 mm calcium or after 30 min, when stimulation was carried out with 0.91 mm calcium. The activity of the released LTD4-dipeptidase was modulated by various metal ions and other compounds. The addition of Mn2+ Co2+, and Zn2+ (final concentration 1 mm) enhanced the LTD4-dipeptidase activity, while Cu2+ led to a complete inhibition. In the absence of exogenoas calcium EDTA inhibited LTD4-dipeptidase. Calcium up to a concentration of 5 and 10mm decreased the dipeptidase activity. The LTD4-dipeptidase is not affected by bestatin, leupeptin. or N-ethyl-maleinimide (NEM). The Km of LTD4-dipeptidase for LTD4 was 0.95±0.2μm and vmax was 737.5±112.5 pmol/min × mg protein (n = 3±SEM). The highest LTD4dipeptidase activity was obtained at physiological pH values. LTD4-dipeptidase activity can also be released from other cell types, but the enzyme activity from human PMN exceeded that of other cells (e.g. human lymphocytes/monocytes and basophils (LMB) and human lung cell suspension).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3083.1987.tb01076.x
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  • 8
    Electronic Resource
    Electronic Resource
    Generation of Cell-Derived Factors Suppressing IgE Synthesis of Nippostrongylus brasiliensis-Infected Mice in Vitro (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 24 (1986), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Modulation of de novo IgE synthesis in vitro was studied using the parasitic infection of mice with the nematode Nippostrongylus brasiliensis. Cell-derived factors were generated by stimulation of splenic and mesenteric lymph node cells of BALB/c mice with monoclonal IgE in vitro. High molecular weight (〉50,000) and low molecular weight (〈50,000) culture superna-tants were prepared. De novo IgE synthesis of BALB/c lymphocytes-obtained from N. brasiliensis-reinfected mice that secreted pronounced quantities of IgE in vitro-was markedly reduced by the addition of high molecular weight supernatants. A dose-dependent suppression of IgE synthesis was obtained, whereas IgG synthesis, viability, and cell proliferation were not inhibited. After fractionation of low molecular weight supernatants with IgE-Sepharose the glycine/HCl eluate fractions markedly inhibited the in vitro IgE synthesis. Low molecular weight factors which suppressed IgE synthesis without modulating IgG production were obtained from IgE high responder B6D2F1 normal mouse cells. Thus, our results demonstrate the generation of IgE-specific suppressor factors in vitro upon stimulation with IgE. The suppression of IgE synthesis by eluate fractions of low molecular weight supernatants absorbed with IgE-Sepharose suggest a potential role for IgE binding factors on de novo IgE synthesis in vitro.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3083.1986.tb02168.x
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  • 9
    Electronic Resource
    Electronic Resource
    Corrections - Mass Spectrometry of Trifluoroacetyl Derivatives of Nucleosides and Hydrolysates of Deoxyribonucleic Acid (1972)
    s.l. : American Chemical Society
    Biochemistry 11 (1972), S. 1122-1122 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00756a602
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  • 10
    Electronic Resource
    Electronic Resource
    Koenig Potash Bulb (1911)
    s.l. : American Chemical Society
    Industrial & engineering chemistry 3 (1911), S. 113-113 
    Details
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ie50026a027
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