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  • 1
    Digitale Medien
    Digitale Medien
    Stimulation of human fetal astrocyte proliferation by bacterial lipopolysaccharides and lipid A (1991)
    Springer
    Acta neuropathologica 82 (1991), S. 384-388 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Bacterial endotoxin ; Lipopolysaccharide ; Lipid A ; Culture astrocyte
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary This report concerns the effect of bacterial endotoxin [lipopolysaccharide(LPS) and lipid A] on cultured human fetal astrocytes. Exposure to 1 μg/ml LPS or lipd A caused a striking stimulation of the rate of proliferation of the cells. The effect was most pronounced with exponentially growing cultures. Stimulation was associated with enhance DNA synthesis as ascertained by [3H]thymidine incorporation. These findings at the cellular level may be of relevance in the elucidation of the effects of bacterial endotoxins on the developing human brain.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00296549
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  • 2
    Digitale Medien
    Digitale Medien
    Computed tomography in congenital ocular motor apraxia (1984)
    Springer
    Neuroradiology 26 (1984), S. 359-362 
    Details
    ISSN: 1432-1920
    Schlagwort(e): Computed tomography ; congenital occular motor apraxia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Unusual computed tomographic findings were observed in four patients with congenital ocular motor apraxia (COMA). These (CT) findings were characteristic in the posterior cranial fossa, with a dilated or deformed shape and size of the fourth ventricle, particularly its upper portion. One case revealed partial agenesis of the cerebellar vermis. It was suggested that the four patients subjected to CT showed abnormal topography of the cerebellar vermis or the brain stem. We postulate that these CT findings in COMA may have an important role in its pathogenesis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00327487
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  • 3
    Digitale Medien
    Digitale Medien
    Intracranial calcification in siblings with nephrogenic diabetes insipidus: CT and MRI (1993)
    Springer
    Neuroradiology 35 (1993), S. 553-555 
    Details
    ISSN: 1432-1920
    Schlagwort(e): Nephrogenic diabetes insipidus ; Intracranial calcification ; Brain damage ; Computed tomography ; Magnetic resonance imaging
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Computed tomography and magnetic resonance imaging (MRI) were used to examine three male siblings with nephrogenic diabetes insipidus (NDI). The two elder brothers had verying degrees of unusual intracranial calcification; the eldest also showed involvement of the cerebral white matter on MRI. The severity of intracranial calcification was related to the time before initiation of treatment and inversely to mental ability. Brain damage and mental retardation in NDI may be caused by a delay in initiating treatment; early detection and treatment are important to prevent brain damage.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00588723
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  • 4
    Digitale Medien
    Digitale Medien
    Focal vulnerability of developing brain: CT studies on disproportionally dilated lateral ventricles (1986)
    Springer
    Neuroradiology 28 (1986), S. 30-33 
    Details
    ISSN: 1432-1920
    Schlagwort(e): Computed tomography ; Ventricular dilatation ; Colpocephaly ; Brain damage
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Cranial computed tomography (CT) of 108 cases with dilated lateral ventricles was reviewed to elucidate the relationship between focal vulnerability of developing brain and disproportional dilatation of lateral ventricles. CT findings of 108 cases with symmetrical dilatation of lateral ventricles were classified into three types by morphometry of lateral ventricles: anterior horn predominant type (31 cases), diffuse type (36 cases), posterior horn predominant type (41 cases). Posterior horn predominant type has a tendency to occur in congenital anomalies and premature brain damage, and anterior horn predominant type in infantile brain damage. This disproportional dilatation of anterior or posterior horns suggests a vulnerability of periventricular structure in developing brain.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00341762
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