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  • 1
    Electronic Resource
    Electronic Resource
    New technique for producing highly uniform droplet streams over an extended range of disturbance wavenumbers (1987)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 58 (1987), S. 279-284 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A recent discovery about a well-studied phenomenon leads to the formation of ultracoherent streams of liquid drops. A remarkably straightforward, although previously unreported, method of drop generation from capillary streams, which involves the imposition of an amplitude modulated sinusoidal carrier disturbance, is discussed. The amplitude-modulated disturbance results in the production of highly stable droplet streams over a previously unattainable range of wavenumbers. A decrease in the speed variation of the drops within the stream, which is a result of the amplitude modulation, is demonstrated over a range of nondimensional wavenumbers from 0.4 to 0.04. The nondimensional wavenumber is the ratio of stream circumference to disturbance wavelength. It is suggested that amplitude modulating the capillary stream's disturbance may also decrease the diameter variation of the drops.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1139322
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The manipulation of capillary stream breakup using amplitude-modulated disturbances: A pictorial and quantitative representation (1990)
    New York, NY : American Institute of Physics (AIP)
    Physics of Fluids 2 (1990), S. 1124-1140 
    Details
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Droplet formation from capillary streams of viscous low vapor pressure fluids in a vacuum has been studied. A new form of capillary stream breakup, which entails the use of an amplitude-modulated sinusoidal disturbance, has been employed extensively in this work. The genesis of droplets formed due to an amplitude-modulated disturbance on a stream is reviewed in some detail and illustrated pictorially. Because capillary stream breakup and subsequent droplet propagation took place in a vacuum there were no significant interactions with the surrounding atmosphere. Sensitive measurements of the relative speeds of each drop have been made by allowing them to travel 6 m in a vertical vacuum chamber, and measuring the time between drops using an optical method. Speed differences as low as 3.5×10−7 times the average stream speed have been measured. New information about capillary stream breakup is inferred by comparing the speed variations for droplet streams generated with both amplitude-modulated disturbances and single-frequency disturbances. An autoregressive model is developed and found to represent the deviations in time between droplets with consistency and reproducibility.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.857612
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    CLINICAL IMPLICATIONS OF ENZYME INDUCTION (1971)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 179 (1971), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1971.tb46919.x
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  • 4
    Electronic Resource
    Electronic Resource
    Interactions between oral contraceptive steroids and broad-spectrum antibiotics (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 11 (1986), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1986.tb00471.x
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  • 5
    Electronic Resource
    Electronic Resource
    The in-vitro mucosal conjugation of ethinyloestradiol and the bioavailability of oral contraceptive steroids in patients with treated and untreated coeliac disease (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 6 (1992), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The ethinyloestradiol (EO2) component of oral contraceptive steroids is extensively conjugated with sulphate by the gut wall. The ability of gastrointestinal mucosa to conjugate EO2 has been examined in vitro in samples of mucosa taken from normal women as well as from women with coeliac disease. The percentage conjugation per mg dry weight for normal tissue (n= 11) was 17.1 ± 6.4 (mean ± s.d.) while in untreated coeliac tissue (n= 6) the figure was 6.3 ± 3.6% (P 〈 0.01). In tissue from patients with treated coeliac disease (n= 5) the figure was 12.1 ± 3.2%.Thus the ability of intestinal mucosa to conjugate ethinyloestradiol was significantly reduced in patients with coeliac disease, and restored towards normal following treatment. However, in patients with coeliac disease the pharmacokinetics of ethinyloestradiol were not significantly different from normal controls.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.1992.tb00547.x
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  • 6
    Electronic Resource
    Electronic Resource
    Capillary column gas-liquid chromatographic-mass spectrometric assay for 7α-hydroxy-5,11-diketotetranorprostane-1,16-dioic acid, the major human urinary metabolite of prostaglandins E"1 and E"2
    Amsterdam : Elsevier
    Journal of Chromatography B: Biomedical Sciences and Applications 181 (1980), S. 85-89 
    Details
    ISSN: 0378-4347
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0378-4347(00)81272-4
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  • 7
    Electronic Resource
    Electronic Resource
    Effect of the progestogens, gestodene, 3-keto desogestrel, levonorgestrel, norethisterone and norgestimate on the oxidation of ethinyloestradiol and other substrates by human liver microsomes
    Amsterdam : Elsevier
    The @Journal of Steroid Biochemistry and Molecular Biology 38 (1991), S. 219-225 
    Details
    ISSN: 0960-0760
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0960-0760(91)90129-S
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  • 8
    Electronic Resource
    Electronic Resource
    Experiments on the dynamics of droplet collisions in a vacuum (2000)
    Springer
    Experiments in fluids 29 (2000), S. 347-358 
    Details
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Highly controlled experiments of binary droplet collisions in a vacuum environment are performed in order to study the collision dynamics devoid of aerodynamic effects that could otherwise obstruct the experimental observations by causing distortion or even disintegration of the coalesced mass. Pre-collision droplets are generated from capillary stream break-up at wavelengths much larger than those generated with the typical Rayleigh droplet formation in order to reduce the interactions among the collision products. Experimental results show that the range of droplet Weber number necessary to describe the boundaries between permanent coalescence and coalescence followed by separation is several orders of magnitude higher than has been reported in experiments conducted at standard atmospheric pressures with lower viscosity liquids (i.e. hydrocarbon fuels and water). Additionally, the time periods of both the oblate and prolate portions of the coalesced droplet oscillation have been measured and it is reported for the first time that the time period for the prolate portion of the oscillation grows exponentially with the Weber number. Finally, new pictorial results are presented for droplet collisions between non-spherical droplets.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003489900092
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  • 9
    Electronic Resource
    Electronic Resource
    Chloroquine in malaria (1993)
    Springer
    European journal of clinical pharmacology 44 (1993), S. 271-274 
    Details
    ISSN: 1432-1041
    Keywords: Chloroquine ; Malaria ; prophylaxis schedules ; side effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Two antimalarial prophylactic regimens were compared in healthy subjects belonging to the flying personnel of Scandinavian Airlines System. Regimen I: 310 mg chloroquine (CQ) base was given once weekly, starting the week prior to departure to the endemic area, then weekly during presence there and for four weeks after return. Regimen II: a loading dose of 620 mg chloroquine base was given at the latest 48 h prior to departure to the endemic area, followed by 310 mg base weekly throughout the visit. Blood samples were analysed by HPLC for CQ and its major metabolite desethylchloroquine (CQM). Regimen I gave suboptimal whole blood concentrations of CQ and CQM at the end of the first week of treatment. Regimen II gave prophylactic concentrations from the beginning of visit up to 6 weeks after departure from the endemic area. Both regimens were well tolerated, but Regimen II appeared better accepted by the volunteers due to its shorter duration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00271370
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  • 10
    Electronic Resource
    Electronic Resource
    The effects of long term administration of dopamine on renal function in hypertensive patients (1973)
    Springer
    European journal of clinical pharmacology 6 (1973), S. 150-155 
    Details
    ISSN: 1432-1041
    Keywords: Dopamine ; renal blood flow ; hypertension ; renal failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effect of an intravenous infusion of dopamine (0.5 to 1.25 µg/kg/min) for periods of between 36 and 105h has been studied in eight patients with hypertension and varying degrees of renal impairment. There was a significant rise in the glomerular filtration rate (GFR) from 31.2±20.2 to 42.8±26.8 ml/min (p〈.05) after four hours of the infusion but after 48 h of infusion the mean GFR was no different from the control value. The paraaminohippuric acid (PAH) clearance also rose from 129.8±115.4 ml/min to 173.1±164.3 ml/min (p〈0.05) after four hours of infusion, but like the GFR it was no different from control after 48 h of the infusion. The daily urine volumes increased significantly during the dopamine infusion from 2176.0±49.2 ml/day to 3809.0±118.8 ml/day (p〈0.002) but had returned to control values after 48 h of continuing dopamine infusion. Following the end of the infusion there was a significant reduction in the urine volume to 1213.0±195.0 ml/day (p〈0.001). There was a rise in sodium excretion during the dopamine infusion from 94.8±50.7 meq/day to 264.7±172.8 meq/day (p〈0.01) with a fall after the end of the infusion to 33.2±27.5 meq/day (p〈0.05). There was no change in the blood urea during the dopamine infusion but after stopping the infusion the blood urea rose from 83.5±39.4 mg% to 95.1±39.0 mg% (p〈0.02). We conclude that intravenous infusion of dopamine to patients with hypertension and renal impairment may produce initial clinical improvement but is of little therapeutic benefit when given for prolonged periods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00558278
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