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Digitale Medien

Neuronal activity in the lateral vestibular nucleus of the cat (1975)

Bruggencate, G. ; Teichmann, R. ; Weller, E.

Springer

Pflügers Archiv 360 (1975), S. 301-320

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ISSN: 1432-2013

Schlagwort(e): Cerebellar afferents ; Deiters neurones ; Postsynaptic potentials ; Purkinje cell inhibition ; Somatic afferents

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary The synaptic input to Deiters neurones evoked by stimulation of peripheral somatic nerves was measured by intracellular recordings. EPSPs with broad receptive fields and latencies which indicate polysynaptic connexions were commonly evoked from the FRA. In other cells, low threshold cutaneous afferents were effective at rather short latencies suggesting oligosynaptic connexions from fast ascending fibres. One example was found of EPSPs due to low threshold muscle afferents. IPSPs due to climbing fibre activation of Purkinje cells as observed in most of the neurones were evoked by cutaneous volleys above 1.5–2.0 T and muscle volleys above 5T (above 3–3.5T in case of Q). Often, IPSPs were evoked by stimulation of nerves, to the segmental level of which the vestibulospinal neurone under investigation projected. A small proportion of cells received short latency IPSPs involving direct fast mossy fibre tracts, which were evoked from low threshold cutaneous afferents. IPSPs due to polysynaptic mossy fibre activation of Purkinje cells were evoked from the FRA bilaterally and from ipsilateral cutaneous afferents at 1.5–2.0T (“prolonged inhibition”). Prolonged excitatory/inhibitory events mediated by mossy fibre pathways may be involved in quadruped locomotion or tother processes making use of a broad motor integration.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00579322

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Digitale Medien

312. Verhalten von Magensäure und Serum-Gastrin bei Streßulcus-gefährdeten Patienten (1981)

Teichmann, R. K. ; Finke, U. ; Hildebrandt, U. ; [weitere]

Springer

Langenbeck's archives of surgery 355 (1981), S. 652-652

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ISSN: 1435-2451

Schlagwort(e): Patients with organ failure ; Acid secretion ; Gastrin ; Acid inhibitory drugs ; Patienten mit Organinsuffizienz ; Säuresekretion ; Gastrin ; Säurehemmende Medikamente

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Beschreibung / Inhaltsverzeichnis: Zusammenfassung Bei 9 Patienten auf der Intensivstation unserer Klinik mit einer oder mehrfacher Organinsuffizienz betrug die mittlere Säuresekretion/h unter Placebo 31 mEq, Cimetidin (8 × 200 mg i.v.) 7,5 mEq, Pirenzepin (4 × 10 mg i.v.) 22 mEq und Cimetidin + Pirenzepin 4,0 mEq. Alle Patienten zeigten eine Hypergastrinämie, die unter Placebo als auch unter der Medikamenten-Gabe bestehen blieb. Die erhöhten Gastrinwerte könnten einen Stimulus für die hohe Säuresekretion in diesen Streßulcus gefährdeten Patienten darstellen.

Notizen: Summary In nine patients at our intensive care unit with one or multiple organ failure, mean acid secretion/h was measured with placebo 31 mEq, cimetidine (8 × 200 mg IV) 7.5 mEq, pirenzepine (4 × 10 mg IV) 22 mEq and cimetidine + pirenzepine 4.0 mEq. All patients showed hypergastrinemia that was present under placebo as well as drug regimen. Increased gastrin might be one stimulus for increased acid secretion in these high-risk patients for stress ulceration.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01287146

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