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  • gastric cancer  (3)
  • Dedifferentiated leiomyosarcoma  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Endosalpingiosis of Nonmetastatic Lymph Nodes Along the Stomach in a Patient with Early Gastric Cancer: Report of a Case (1999)
    Springer
    Surgery today 29 (1999), S. 264-265 
    Details
    ISSN: 1436-2813
    Schlagwort(e): Key Words: endosalpingiosis ; lymph node ; gastric cancer
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s005950050400
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  • 2
    Digitale Medien
    Digitale Medien
    Endosalpingiosis of nonmetastatic lymph nodes along the stomach in a patient with early gastric cancer: Report of a case (1999)
    Springer
    Surgery today 29 (1999), S. 264-265 
    Details
    ISSN: 1436-2813
    Schlagwort(e): endosalpingiosis ; lymph node ; gastric cancer
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We report herein the case of a 32-year-old woman who underwent distal gastrectomy with D2 lymph node dissection for gastric cancer. Microscopic examination of the resected specimen revealed signet-ring cell carcinoma of the stomach with lymph node metastases, and endosalpingiosis in the normal lymph nodes. There was no evidence of malignancy in the peritoneal cavity. To our knowledge, no other case of endosalpingiosis in the lymph nodes along the stomach has ever been reported. The possible significance of endosalpingiosis is discussed following this case report.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02483018
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  • 3
    Digitale Medien
    Digitale Medien
    Dedifferentiated leiomyosarcoma of the intestinal tract: histological, ultrastructural and immunohistochemical examinations (1992)
    Springer
    Virchows Archiv 420 (1992), S. 313-320 
    Details
    ISSN: 1432-2307
    Schlagwort(e): Dedifferentiated leiomyosarcoma ; Intestinal tract ; Dedifferentiated element ; Immunohistochemistry
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Six cases of dedifferentiated leiomyosarcoma of the small and large bowel are presented with histological, ultrastructural and immunohistochemical examination. One case arose in the jejunum, two in the ileum, and the other three in the large intestine. The tumours were submucosal in four cases with large areas of ulceration; two were polypoid. Four tumours showed typical leiomyosarcomatous appearance with dedifferentiated components and two were typical leiomyosarcomas at the primary site with differentiated components only in metastatic foci. By immunohistochemistry, typical leiomyosarcomatous areas showed a positive reaction for muscle-specific actin (MSA), MB1, MB2 and myosin. In contrast, desmin-positive cells were scattered throughout the tumour or were not present. Tumour cells in dedifferentiated components were positive for alpha-1-antitrypsin and alpha-1-antichymotrypsin in all cases but one; neuron specific enolase, MB1, MB2 and myosin were positive with variety. MSA was faintly positive in only a few tumour cells of two cases and desmin was not detected in any of the cases studied. Ultrastructurally, tumour cells in typical leiomyosarcomatous areas demonstrated evident smooth muscle features, although in dedifferentiated areas they lacked such features except in one case. Our results indicate that dedifferentiated elements may derive from ordinary leiomyosarcoma and loose muscle features due to dedifferentiation.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01600210
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  • 4
    Digitale Medien
    Digitale Medien
    Alpha-fetoprotein-producing gastric carcinoma: Biological properties of a cultured cell line (1995)
    Springer
    Journal of gastroenterology 30 (1995), S. 589-598 
    Details
    ISSN: 1435-5922
    Schlagwort(e): cultured cell line ; gastric cancer ; alpha-fetoprotein ; tumor marker
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We describe a gastric carcinoma cell line that has been maintained in vitro for more than 10 years and retains the capacity to produce a large amount of alpha-fetoprotein. This cell line was isolated from a metastatic lymph node of a 63-year-old male patient with advanced gastric carcinoma (T2N3P0H0M0) who showed high serum levels of alpha-fetoprotein. The primary tumor was moderately differentiated tubular adenocarcinoma and the lymph node was poorly differentiated adenocarcinoma without any particular pattern. The cultured cells grew as densely packed islet-like colonies with small polygonal cells. Electron microscopy revealed cells abundant in cytoplasmic organelles, with some cellular attachments being tight with junctional complexes and some being loose across intercellular spaces. The free cell surface had microvilli. The population doubling-time was 152 h at passage 58. Chromosomal analysis revealed the modal number to be 77, with numerous karyotype abnormalities. The tumorigenicity of the cultured cells in athymic nude mice was positive only when they were subcutaneously transplanted beneath a plastic plate, but when the cells were transplanted subcutaneously or administered by intrasplenic injection in intact or weakly irradiated nude mice, no tumorigenicty was shown. The cell line produced tumor-associated antigens, such as alpha-fetoprotein, carcinoembryonic antigen, and tissue polypeptide antigen. This cell line may be useful for comparative studies of different types of gastric carcinoma and alpha-fetoproteins of different origins.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02367784
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